Euro
USD
British Pound
NULL
Product Description
LGR5 Antibody | 13-711 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 824-907 of human LGR5 (NP_003658.1) .
Research Area: Cancer, Signal Transduction, Stem Cell
Tested Application: WB, IF
Application: WB: 1:1000 - 1:2000
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: HT-29
Positive Control 2: HepG2
Positive Control 3: SKOV3
Positive Control 4: A-431
Positive Control 5: Mouse brain
Positive Control 6: Rat brain
Molecular Weight: Observed: 105kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: Leucine-rich repeat-containing G-protein coupled receptor 5, G-protein coupled receptor 49, G-protein coupled receptor 67, G-protein coupled receptor HG38, LGR5, GPR49, GPR67
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The protein encoded by this gene is a leucine-rich repeat-containing receptor (LGR) and member of the G protein-coupled, 7-transmembrane receptor (GPCR) superfamily. The encoded protein is a receptor for R-spondins and is involved in the canonical Wnt signaling pathway. This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development. Several transcript variants encoding different isoforms have been found for this gene.
