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Product Description
PARP1 Antibody, KO Validated | 13-327 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 81-390 of human PARP1 (NP_001609.2) .
Research Area: Cell Cycle, Immunology, Signal Transduction
Tested Application: WB, IHC, IF, IP, CHIP
Application: WB: 1:1000 - 1:3000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
IP: 1:50 - 1:200
CHIP: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: Jurkat
Positive Control 2: HeLa
Positive Control 3: RAW264.7
Positive Control 4: C6
Positive Control 5: Mouse testis
Positive Control 6: Mouse brain
Molecular Weight: Observed: 100kDa, 110kDa, 125kDa
Validation: Antibody is Knockout validated.
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: KIF3B, PARP, PPOL, ADPRT, ARTD1, ADPRT1, PARP-1, ADPRT 1, pADPRT-1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a chromatin-associated enzyme, poly (ADP-ribosyl) transferase, which modifies various nuclear proteins by poly (ADP-ribosyl) ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
![[KO Validated] PARP1 Polyclonal Antibody](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/295472/455609/sab-signalway-antibody__92073.1641690747__95898.1641691412.gif?c=2 "[KO Validated] PARP1 Polyclonal Antibody")
