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Product Description
AMT Antibody | 26-849 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat, Dog
Homology: N/A
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human AMT.
Research Area: Other
Tested Application: E, WB
Application: AMT antibody can be used for detection of AMT by ELISA at 1:12500. AMT antibody can be used for detection of AMT by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Specificiy: N/A
Positive Control 1: Cat. No. XBL-10410 - Fetal Lung Tissue Lysate
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 44 kDa
Validation: N/A
Isoform: N/A
Purification: Antibody is purified by peptide affinity chromatography method.
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration: batch dependent
Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store AMT antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Alternate Name: AMT, GCE, GCST, NKH, GCVT
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10) , which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase) , H protein (a lipoic acid-containing protein) , T protein (a tetrahydrofolate-requiring enzyme) , and L protein (a lipoamide dehydrogenase) . Glycine encephalopathy (GCE) may be due to a defect in any one of these enzymes.The enzyme system for cleavage of glycine (glycine cleavage system; EC 2.1.2.10) , which is confined to the mitochondria, is composed of 4 protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase; MIM 238300) , H protein (a lipoic acid-containing protein; MIM 238330) , T protein (a tetrahydrofolate-requiring enzyme) , and L protein (a lipoamide dehydrogenase; MIM 238331) . Glycine encephalopathy (GCE; MIM 605899) may be due to a defect in any one of these enzymes.
