Product Description
Exportin 4 Antibody | 33-057 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: A recombinant protein fragment from the C-terminal portion of Exportin 4 was used as the immunogen for this antibody.
Research Area: Signal Transduction
Tested Application: WB
Application: Western blot: 1-3 ug/ml
Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein A affinity chromatography
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.5 mg/mL
Storage Condition: Aliquot and Store at -20˚C. Avoid freez-thaw cycles.
Alternate Name: N/A
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: Importins and exportins are transport receptors carrying cargo molecules into and out of the nucleus. Exportin 4 is a member of the Importin B superfamily of RanGTP-binding proteins. Its homology to other family members is restricted to its N-terminal RanGTP-binding motif. Exportin 4 is a nuclear export receptor for eIF-5A, a protein involved in the cellular stress response, functioning as a regulator of p53-mediated and TNF-alpha-mediated apoptosis.