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Product Description
GPR77 Antibody | 33-046 | ProSci
Host: Rabbit
Reactivity: Human, Primate
Homology: N/A
Immunogen: A recombinant protein fragment from the N-terminal region of human GPR77 was used as the immunogen for this antibody.
Research Area: Signal Transduction
Tested Application: WB
Application: Western blot: 1-3 ug/ml
Provided assay concentrations are suggestions only, GPR77 antibody titration may be required for optimal results.
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Protein A Affinity Chromatography
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide
Concentration: 0.5 mg/mL
Storage Condition: Aliquot and Store at -20˚C. Avoid freez-thaw cycles.
Alternate Name: N/A
User Note: Optimal dilutions for each application to be determined by the researcher
BACKGROUND: G protein receptors, also called GPRs, GPCRs, and seven-transmembrane domain receptors, are a large family of receptors with possibly over 800 members. These receptors sense stimuli outside, convey the signal across the cell membrane, and activate internal signal transduction pathways and cellular responses. GPR77 is involved in the complement system of the innate immune response and may signal through the beta-arrestin pathway, and possibly act as a decoy receptor. It is co-expressed with the C5a receptor on neutrophils and may modulate C5a1 activity.
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