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Product Description
TFAM Antibody | 28-597 | ProSci
Host: Rabbit
Reactivity: Mouse
Homology: N/A
Immunogen: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of mouse TFAM.
Research Area: Transcription
Tested Application: E, WB
Application: TFAM antibody can be used for detection of TFAM by ELISA at 1:62500. TFAM antibody can be used for detection of TFAM by western blot at 0.06 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50, 000 - 100, 000.
Specificiy: N/A
Positive Control 1: Cat. No. 1282 - 3T3 (NIH) Cell Lysate
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 27 kDa
Validation: N/A
Isoform: N/A
Purification: Antibody is purified by peptide affinity chromatography method.
Clonality: Polyclonal
Clone: N/A
Isotype: N/A
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration: batch dependent
Storage Condition: For short periods of storage (days) store at 4˚C. For longer periods of storage, store TFAM antibody at -20˚C. As with any antibody avoid repeat freeze-thaw cycles.
Alternate Name: TFAM, Hmgts, mtTFA, tsHMG, AI661103
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: TFAM a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this protein is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns Sayre syndrome was produced when expression of the gene was eliminated by targeted disruption in heart and muscle cells.
