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Product Description
YARS Antibody | 22-489 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human YARS (NP_003671.1) .
Research Area: Apoptosis, Cell Cycle, Chemokines & Cytokines, Immunology
Tested Application: WB, IP
Application: WB: 1:500 - 1:2000
IP: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: HeLa
Positive Control 2: SKOV3
Positive Control 3: Mouse brain
Positive Control 4: Mouse skeletal muscle
Positive Control 5: Rat brain
Positive Control 6: N/A
Molecular Weight: Observed: 59kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: YARS, YRS, YTS, TYRRS, CMTDIC
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Tyrosyl-tRNA synthetase belongs to the class I tRNA synthetase family. Cytokine activities have also been observed for the human tyrosyl-tRNA synthetase, after it is split into two parts, an N-terminal fragment that harbors the catalytic site and a C-terminal fragment found only in the mammalian enzyme. The N-terminal fragment is an interleukin-8-like cytokine, whereas the released C-terminal fragment is an EMAP II-like cytokine.
