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![CD24 Antibody [30-F1]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/576665/814553/porsci_lo__79508.1648973713__11650.1649092242.png?c=2 "CD24 Antibody [30-F1]")
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Product Description
CD24 Antibody [30-F1] | 98-985 | ProSci
Host: Rat
Reactivity: Mouse
Homology: N/A
Immunogen: Mouse thymus or spleen
Research Area: Immunology
Tested Application: Flow, IP
Application: CD24 Antibody [30-F1] for use in flow cytometry assays.
Specificiy: CD24
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [30-F1]
Isotype: IgG2c
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in PBS
Concentration: 0.5 mg/mL
Storage Condition: Store vial at -20˚C
Alternate Name: Heat stable antigen, HSA
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD24 is expressed in B cells until their terminal differentiation into plasma cells. It has been used widely as a marker to fractionate different B-lineage differentiation stages. CD24 has been found on a variety of other hematopoietic and neural cell types and is now classified as a costimulatory molecule. The CD24 molecule, also known as HSA, is composed mostly of carbohydrate with a protein core of only 31-35 amino acids in the human and 27 amino acids in the mouse. CD24 is now included in the large group of phosphatidylinositol-anchored membrane proteins. Studies with purified CD24 applied to latex beads have demonstrated a self-binding property suggesting that the molecule is capable of promoting homotypic aggregation, binding, and cell adhesion. This is supported by earlier observations of the blockade of B cell lymphoblast aggregation with an anti-CD24 monoclonal antibody. Recent studies of murine CD24 have assigned a role for CD24 as a ligand for P-selectin, a calcium-dependent lectin.
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