Product Description
CD49e Antibody [5H10.27] (PE) | 98-810 | ProSci
Host: Rat
Reactivity: Mouse
Homology: N/A
Immunogen: C57BL/6 x A/J F1 mouse mast cell line MC/9
Research Area: Cancer, Signal Transduction
Tested Application: E, WB, IHC-Fr, ICC, Flow, Blocking, Cytotoxicity
Application: CD49e Antibody [5H10.27] for use in flow cytometry assays.
Specificiy: CD49e
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [5H10.27]
Isotype: IgG2a
Conjugate: PE
Physical State: Liquid
Buffer: Supplied in PBS/NaN3 and a stabilizing agent
Concentration: 0.1 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: Integrin alpha5, VLA-5alpha
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The monoclonal antibody 5H10.27 reacts with the alpha5 chain (VLA-5) of the CD49e/CD29 heterodimeric fibronectin receptor. It is expressed on thymocytes, activated T cells, mast cells, and a variety of mouse cell lines. Soluble 5H10.27 antibody inhibits VLA-5-mediated functions in vitro. Immobilized 5H10.27 has also been demonstrated to costimulate the proliferative response of CD8+ T cells to plate-bound anti-CD3 monoclonal antibody.