Euro
USD
British Pound
NULL
![CD5 Antibody [B19.1]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/576454/814256/porsci_lo__79508.1648973713__15337.1649092202.png?c=2 "CD5 Antibody [B19.1]")
![CD5 Antibody [B19.1]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/576454/814256/porsci_lo__79508.1648973713__15337.1649092202.png?c=2 "CD5 Antibody [B19.1]")
Product Description
CD5 Antibody [B19.1] | 98-596 | ProSci
Host: Rat
Reactivity: Mouse
Homology: N/A
Immunogen: N/A
Research Area: Cancer, Immunology, Signal Transduction
Tested Application: E, WB, IHC-P, IHC-Fr, Flow
Application: CD5 Antibody [B19.1] for use in flow cytometry, western blotting, and immunoprecipitation assays.
Specificiy: CD5
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [B19.1]
Isotype: IgG2a
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration: 0.5 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: Lyt-1, Ly-1, Lymphocyte antigen 1, Ly-12, Ly-A, T1, Tp67
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD5, also known as Lyt-1, is a monomeric type I transmembrane glycoprotein expressed on thymocytes, T lymphocytes, and a subset of B lymphocytes, but not on natural killer (NK) cells. It has been identified as the major ligand of the B-cell antigen CD72. The frequency of CD5+ B cells exhibits strain-dependent variation, and the phenotypic, anatomical, functional, developmental, and pathological characteristics of the CD5+ B cells suggest that they may represent a distinct lineage, known as B-1 cells. Binding of CD5 on the T cell surface can augment alloantigen- or mitogen-induced lymphocyte proliferation and induces increased cytosolic free calcium, IL-2 secretion, and IL-2R expression. It has been proposed that CD5 negatively regulates signal transduction mediated by the T-cell and B-cell receptors.
![CD5 Antibody [B19.1]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/576454/814256/porsci_lo__79508.1648973713__15337.1649092202.png?c=2 "CD5 Antibody [B19.1]")
![CD5 Antibody [B19.1] (FITC)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/576455/814257/porsci_lo__79508.1648973713__77792.1649092202.png?c=2 "CD5 Antibody [B19.1] (FITC)")
![CD5 Antibody [B19.1] (APC)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/576023/813538/porsci_lo__79508.1648973713__16636.1649092105.png?c=2 "CD5 Antibody [B19.1] (APC)")
![CD5 Antibody [B19.1] (Biotin)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/576456/814258/porsci_lo__79508.1648973713__47103.1649092202.png?c=2 "CD5 Antibody [B19.1] (Biotin)")
![CD5 Antibody [B19.1] (PE)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/576022/813536/porsci_lo__79508.1648973713__91844.1649092105.png?c=2 "CD5 Antibody [B19.1] (PE)")
![CD5 Antibody [B19.1] (PE-Cy5)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/576024/813539/porsci_lo__79508.1648973713__37097.1649092105.png?c=2 "CD5 Antibody [B19.1] (PE-Cy5)")