Euro
USD
British Pound
NULL
![CD71 Antibody [RI7217] (FITC)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/576576/814433/porsci_lo__79508.1648973713__73089.1649092225.png?c=2 "CD71 Antibody [RI7217] (FITC)")
![CD71 Antibody [RI7217] (FITC)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/100x100/products/576576/814433/porsci_lo__79508.1648973713__73089.1649092225.png?c=2 "CD71 Antibody [RI7217] (FITC)")
Product Description
CD71 Antibody [RI7217] (FITC) | 98-836 | ProSci
Host: Rat
Reactivity: Mouse
Homology: N/A
Immunogen: DMSO induced Friend erythroleukemia 745.6
Research Area: Cancer, Immunology, Obesity, Signal Transduction
Tested Application: Flow
Application: CD71 Antibody [RI7217] for use in flow cytometry, immunocytochemistry, and western blotting assays.
Specificiy: CD71
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [RI7217]
Isotype: IgG2a
Conjugate: FITC
Physical State: Liquid
Buffer: Supplied in PBS/NaN3
Concentration: 0.5 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: T9, transferrin receptor, TfR
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD71, a type II transmembrane glycoprotein expressed on the cell surface as a homodimer, is the transferrin receptor. It is essential for the growth of normal and neoplastic cells. It is expressed at low levels on resting B and T lymphocytes but is upregulated during responses to antigens and mitogens presumably reflecting the iron dependence of proliferation. Its expression declines with maturation and differentiation. CD71 plays a critical role in cell proliferation by controlling the supply of iron which is essential for many metabolic pathways through the binding and endocytosis of transferrin, the major iron-carrying protein. It may also be involved in signal transduction via its association with the T cell receptor ζ chain. The monoclonal antibody RI7217 inhibits cell proliferation in vitro.
![CD71 Antibody [RI7217] (FITC)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/576576/814433/porsci_lo__79508.1648973713__73089.1649092225.png?c=2 "CD71 Antibody [RI7217] (FITC)")
![CD71 Antibody [RI7217]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/576575/814432/porsci_lo__79508.1648973713__69928.1649092225.png?c=2 "CD71 Antibody [RI7217]")
![CD71 Antibody [RI7217]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/576578/814437/porsci_lo__79508.1648973713__70269.1649092226.png?c=2 "CD71 Antibody [RI7217]")
![CD71 Antibody [RI7217] (Biotin)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/576577/814435/porsci_lo__79508.1648973713__80974.1649092226.png?c=2 "CD71 Antibody [RI7217] (Biotin)")
![CD71 Antibody [RI7217] (PE)](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/500x659/products/576133/813741/porsci_lo__79508.1648973713__26665.1649092132.png?c=2 "CD71 Antibody [RI7217] (PE)")
