Product Description
FOXP3 Antibody [MF333F] | 36-024 | ProSci
Host: Rat
Reactivity: Mouse
Homology: N/A
Immunogen: Recombinant mouse FOXP3.
Research Area: Cancer, Immunology
Tested Application: E, ICC, IHC, WB
Application: Western Blot: (1ug/ml) .
Specificiy: Recognizes mouse FOXP3. Detects a band of ~46-49kDa by Western blot.
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: MF333F
Isotype: IgG2a, kappa
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Liquid. 0.2um-filtered solution in PBS, pH 7.4. Contains no preservatives.
Concentration: 1 mg/ml
Storage Condition: Stable for at least 1 year after receipt when stored at -20˚C.
Alternate Name: Forkhead Box Protein P3; Scurfin
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: FOXP3 is involved in immune system responses. It functions as the master regulator in the development and function of regulatory T cells. FOX proteins belong to the forkhead/winged-helix family of transcriptional regulators and are presumed to exert control via similar DNA binding interactions during transcription. Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) ; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema.