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![LPAM-1 Antibody [DATK32]](https://cdn11.bigcommerce.com/s-452hpg8iuh/images/stencil/1280x1280/products/576682/814572/porsci_lo__79508.1648973713__15113.1649092244.png?c=2 "LPAM-1 Antibody [DATK32]")
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Product Description
LPAM-1 Antibody [DATK32] | 99-012 | ProSci
Host: Rat
Reactivity: Mouse
Homology: N/A
Immunogen: AKR/Cum mouse T lymphoma cell line TK-1
Research Area: Immunology, Signal Transduction, Stem Cell
Tested Application: Flow
Application: LPAM-1 Antibody [DATK32] for use in flow cytometry, immunohistochemistry, immunoprecipitation, and blocking assays.
Specificiy: LPAM-1
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [DATK32]
Isotype: IgG2a
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in PBS
Concentration: 0.5 mg/mL
Storage Condition: Store vial at -20˚C
Alternate Name: Integrin alpha4beta7, lymphocyte Peyer's patch adhesion molecule
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The lymphocyte Peyer’s patch adhesion molecule (LPAM-1) , also known as integrin alpha4beta7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes but is also present on NK cells and eosinophils. The alpha4beta7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer’s patches and intestinal lamina propria. The monoclonal antibody DATK32 recognizes a conformational epitope on the heterodimer.
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