Product Description
DDOST Antibody | 23-781 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 40-300 of human DDOST (NP_005207.2) .
Research Area: Other
Tested Application: WB, IHC
Application: WB: 1:500 - 1:2000
IHC: 1:100 - 1:200
Specificiy: N/A
Positive Control 1: U-87MG
Positive Control 2: HT-29
Positive Control 3: HepG2
Positive Control 4: A-549
Positive Control 5: Mouse kidney
Positive Control 6: Mouse liver
Molecular Weight: Observed: 54kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: DDOST, AGE-R1, KIAA0115, MGC2191, OK/SW-cl.45, OST, OST48, WBP1, AGER1, CDG1R, OKSWcl45
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a component of the oligosaccharyltransferase complex which catalyzes the transfer of high-mannose oligosaccharides to asparagine residues on nascent polypeptides in the lumen of the rough endoplasmic reticulum. The protein complex co-purifies with ribosomes. The product of this gene is also implicated in the processing of advanced glycation endproducts (AGEs) , which form from non-enzymatic reactions between sugars and proteins or lipids and are associated with aging and hyperglycemia.