Product Description
Dimethyl-Lysine pAb | 16-915 | ProSci
Host: Rabbit
Reactivity: All Species
Homology: N/A
Immunogen: Dimethyl Protein.
Research Area: Other
Tested Application: WB, IP
Application: WB: 1:500 - 1:1000
IP: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.1% sodium azide and 50% glycerol pH 7.2.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: N/A
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: Protein methylation is a very diverse, widespread and important post-translational modification affecting all aspects of cellular biology in eukaryotes. Methylation on the side chain of lysine residues in histones has received considerable attention due to its major role in chromatin structure and the epigenetic regulation of gene expression。 However, evidence of lysine methylation-driven regulation has been obtained for a number of non-histone proteins since the turn of the 21st century。This modification has been shown to regulate protein-protein and protein-nucleic acid interactions, protein stability, subcellular localization or enzyme activity in essential cellular processes including transcription, protein synthesis, signal transduction and metabolism.