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Product Description
E2F6 Antibody | 22-034 | ProSci
Host: Rabbit
Reactivity: Human, Mouse
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-281 of human E2F6 (NP_937987.2) .
Research Area: Signal Transduction, Transcription
Tested Application: WB, IHC, IF, IP, ChIP
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:20 - 1:100
IP: 1:50 - 1:100
CHIP: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: MCF-7
Positive Control 2: Jurkat
Positive Control 3: HeLa
Positive Control 4: HepG2
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 37kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: E2F6, E2F-6
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a member of a family of transcription factors that play a crucial role in the control of the cell cycle. The protein encoded by this gene lacks the transactivation and tumor suppressor protein association domains found in other family members, and contains a modular suppression domain that functions in the inhibition of transcription. It interacts in a complex with chromatin modifying factors. There are pseudogenes for this gene on chromosomes 22 and X. Alternative splicing results in multiple transcript variants.
