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Product Description
GDI2 Antibody, KO Validated | 23-690 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 296-445 of human GDI2 (NP_001485.2) .
Research Area: Signal Transduction
Tested Application: WB, IF
Application: WB: 1:200 - 1:3000
IF: 1:50 - 1:100
Specificiy: N/A
Positive Control 1: HT-29
Positive Control 2: A-549
Positive Control 3: HepG2
Positive Control 4: U-87MG
Positive Control 5: Mouse spleen
Positive Control 6: Mouse kidney
Molecular Weight: Observed: 51kDa
Validation: Antibody is Knockout validated.
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: GDI2, RABGDIB, HEL-S-46e
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: GDP dissociation inhibitors are proteins that regulate the GDP-GTP exchange reaction of members of the rab family, small GTP-binding proteins of the ras superfamily, that are involved in vesicular trafficking of molecules between cellular organelles. GDIs slow the rate of dissociation of GDP from rab proteins and release GDP from membrane-bound rabs. GDI2 is ubiquitously expressed. The GDI2 gene contains many repetitive elements indicating that it may be prone to inversion/deletion rearrangements. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
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