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Product Description
IRAK4 Antibody | 24-025 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human IRAK4 (NP_057207.2) .
Research Area: Signal Transduction
Tested Application: WB, IHC
Application: WB 1:500 - 1:2000
IHC 1:50 - 1:200
Specificiy: N/A
Positive Control 1: MCF7
Positive Control 2: Jurkat
Positive Control 3: Raji
Positive Control 4: U-251MG
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 55 kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: IRAK-4 Antibody: IPD1, REN64, IRAK-4, NY-REN-64, Interleukin-1 receptor-associated kinase 4, Renal carcinoma antigen NY-REN-64
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.
