Product Description
NPR3 Antibody | 23-425 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 272-541 of human NPR3 (NP_001191304.1) .
Research Area: Cell Cycle, Signal Transduction
Tested Application: WB, IF
Application: WB: 1:1000 - 1:2000
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: A-549
Positive Control 2: Mouse lung
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 60kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: NPR3, OTTHUMP00000220980, OTTHUMP00000197048, NPR-C, NPRC, natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C) , GUCY2B, atrial natriuretic peptide receptor type C, atrial natriuretic peptide receptor 3, atrial natriuretic peptide clearance receptor, ANPR-C, ANPRC, ANP-C, C5orf23
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes one of three natriuretic peptide receptors. Natriutetic peptides are small peptides which regulate blood volume and pressure, pulmonary hypertension, and cardiac function as well as some metabolic and growth processes. The product of this gene encodes a natriuretic peptide receptor responsible for clearing circulating and extracellular natriuretic peptides through endocytosis of the receptor. Multiple transcript variants encoding different isoforms have been found for this gene.