Product Description
NUP133 Antibody | 23-733 | ProSci
Host: Rabbit
Reactivity: Human
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 730-930 of human NUP133 (NP_060700.2) .
Research Area: Signal Transduction
Tested Application: WB, IF
Application: WB: 1:1000 - 1:2000
IF: 1:50 - 1:200
Specificiy: N/A
Positive Control 1: A375
Positive Control 2: LO2
Positive Control 3: HeLa
Positive Control 4: NCI-H460
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 133kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: GAMOS8, NPHS18, hNUP133, nuclear pore complex protein Nup133, 133 kDa nucleoporin, nucleoporin 133kD, nucleoporin 133kDa, nucleoporin Nup133
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: The nuclear envelope creates distinct nuclear and cytoplasmic compartments in eukaryotic cells. It consists of two concentric membranes perforated by nuclear pores, large protein complexes that form aqueous channels to regulate the flow of macromolecules between the nucleus and the cytoplasm. These complexes are composed of at least 100 different polypeptide subunits, many of which belong to the nucleoporin family. The nucleoporin protein encoded by this gene displays evolutionarily conserved interactions with other nucleoporins. This protein, which localizes to both sides of the nuclear pore complex at interphase, remains associated with the complex during mitosis and is targeted at early stages to the reforming nuclear envelope. This protein also localizes to kinetochores of mitotic cells.