Product Description
PAN2 Antibody | 58-634 | ProSci
Host: Rabbit
Reactivity: Human
Homology: Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat
Immunogen: This PAN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 860-888 amino acids from the C-terminal region of human PAN2.
Research Area: Other
Tested Application: WB
Application: For WB starting dilution is: 1:1000
Specificiy: N/A
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: 135 kDa
Validation: N/A
Isoform: N/A
Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.
Clonality: Polyclonal
Clone: N/A
Isotype: Rabbit Ig
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in PBS with 0.09% (W/V) sodium azide.
Concentration: batch dependent
Storage Condition: Store at 4˚C for three months and -20˚C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Alternate Name: PAB-dependent poly (A) -specific ribonuclease subunit PAN2 {ECO:0000255|HAMAP-Rule:MF_03182}, hPan2, 31134 {ECO:0000255|HAMAP-Rule:MF_03182}, Inactive ubiquitin carboxyl-terminal hydrolase 52 {ECO:0000255|HAMAP-Rule:MF_03182}, PAB1P-dependent poly (A) -nuclease {ECO:0000255|HAMAP-Rule:MF_03182}, PAN deadenylation complex catalytic subunit 2 {ECO:0000255|HAMAP-Rule:MF_03182}, PAN2 {ECO:0000255|HAMAP-Rule:MF_03182}, KIAA0710, USP52
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a deadenylase that functions as the catalytic subunit of the polyadenylate binding protein dependent poly (A) nuclease complex. The encoded protein is a magnesium dependent 3' to 5' exoribonuclease that is involved in the degradation of cytoplasmic mRNAs. Alternate splicing results in multiple transcript variants.