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Product Description
RAB7A Antibody | 14-370 | ProSci
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant protein of human RAB7A
Research Area: Signal Transduction
Tested Application: WB, IHC, Flow
Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:100
Flow: 1:20 - 1:50
Specificiy: N/A
Positive Control 1: A-431
Positive Control 2: HeLa
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 23kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, pH7.3.
Concentration: N/A
Storage Condition: Store at 4˚C. Avoid freeze / thaw cycles.
Alternate Name: RAB7A, CMT2B, PRO2706, RAB7, Ras-associated protein RAB7, Ras-related protein Rab-7a, PSN
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: RAB family members are small, RAS-related GTP-binding proteins that are important regulators of vesicular transport. Each RAB protein targets multiple proteins that act in exocytic / endocytic pathways. This gene encodes a RAB family member that regulates vesicle traffic in the late endosomes and also from late endosomes to lysosomes. This encoded protein is also involved in the cellular vacuolation of the VacA cytotoxin of Helicobacter pylori. Mutations at highly conserved amino acid residues in this gene have caused some forms of Charcot-Marie-Tooth (CMT) type 2 neuropathies.
