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Product Description
3,3',5’-Triiodo-L-thyronine (Reverse T3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRα and TRβ than 3,3',5-triiodo-L-thyronine. Reverse T3 positively regulates the hepatic FGF21 expression and stimulates the metabolic breakdown of glucose, fats, and proteins by enhancing the levels of numerous metabolic enzymes such as hexokinase, liver glucose 6-phosphatase as well as mitochondrial enzymes for oxidative phosphorylation.
3,3',5’-Triiodo-L-thyronine (Reverse T3), is a thyroid hormone generated by deiodination of the prohormone thyroxine. It is about 1,000-fold less active at the thyroid hormone receptors TRα and TRβ than 3,3',5-triiodo-L-thyronine.
Biovision | B2017 | 3,3',5'-Triiodo-L-thyronine DataSheet
Alternate Name/Synonyms: O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine, Liothyronine, T3; Reverse T3
Appearance: Off-white solid
Formulation: N/A
CAS Number: 5817-39-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₅H₁₂I₃NO₄
Molecular Weight: 650.97
Cell-Permeable?: Yes
Purity: ≥95%
Solubilities: DMSO (30 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A thyroid hormone
MDL Number: MFCD00036864
PubChem CID: 644280
SMILES: C1=CC(=C(C=C1CC(C(=O)O)N)I)OC2=CC(=C(C(=C2)I)O)I
InChi: InChI=1S/C15H12I3NO4/c16-9-3-7(4-12(19)15(21)22)1-2-13(9)23-8-5-10(17)14(20)11(18)6-8/h1-3,5-6,12,20H,4,19H2,(H,21,22)/t12-/m0/s1
InChi Key: HZCBWYNLGPIQRK-LBPRGKRZSA-N
