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Product Description
Diindolylmethane (DIM) is a natural compound present in food plants of the Brassica genus, including broccoli, cabbage, Brussels sprouts, cauliflower and kale. Displays antitumor and proapoptotic properties in animal and in in vitro models of cancer. Also acts a selective and potent inhibitor of cancer stem cells, and HDAC activity in prostate cancer cells. Recently, it has been shown that DIM induces apoptosis in ovarian cancer cells by inhibiting JAK2/STAT3.
Diindolylmethane (DIM) is a natural compound present in food plants of the Brassica genus, including broccoli, cabbage, Brussels sprouts, cauliflower and kale. Displays antitumor and proapoptotic properties in animal and in in vitro models of cancer. Also acts a selective and potent inhibitor of cancer stem cells, and HDAC activity in prostate cancer cells.
Biovision | 2150 | 3,3'-Diindolylmethane DataSheet
Alternate Name/Synonyms: 3,3’-Methylenediindole; DIM
Appearance: White to Off-white Solid
Formulation: N/A
CAS Number: 1968-05-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₇H₁₄N₂
Molecular Weight: 246.31
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (25 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent inhibitor of cancer stem cells
MDL Number: MFCD00195766
PubChem CID: 3071
SMILES: C1=CC=C2C(=C1)C(=CN2)CC3=CNC4=CC=CC=C43
InChi: InChI=1S/C17H14N2/c1-3-7-16-14(5-1)12(10-18-16)9-13-11-19-17-8-4-2-6-15(13)17/h1-8,10-11,18-19H,9H2
InChi Key: VFTRKSBEFQDZKX-UHFFFAOYSA-N
