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Product Description
3-Deazaadenosine (3-DZA) is an inhibitor of SAH (S-adenosylhomocysteine) hydrolase (Ki = 3.9 μM). It has anti-inflammatory properties, inhibiting leukocyte adhesion and chemotaxis, lymphocyte-mediated cytolysis, phagocytosis, degranulation, and NF-κB signaling. 3-DZA also has anti-viral and anti-bacterial activities.
3-Deazaadenosine (3-DZA) is an inhibitor of SAH (S-adenosylhomocysteine) hydrolase (Ki = 3.9 μM). It has anti-inflammatory properties, inhibiting leukocyte adhesion and chemotaxis, lymphocyte-mediated cytolysis, phagocytosis, degranulation, and NF-κB signaling. 3-DZA also has anti-viral and anti-bacterial activities.
Biovision | 2771 | 3-Deazaadenosine DataSheet
Alternate Name/Synonyms: 1-β-D-ribofuranosyl-1H-Imidazo[4,5-c]pyridin-4-amine; 3-DZA; deaza-Ado; c3Ado
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 6736-58-9
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₁H₁₄N₄O₄
Molecular Weight: 266.25
Cell-Permeable?: Y
Purity: ≥98%
Solubilities: H₂O (~10 mg/ml)
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A SAH hydrolase inhibitor
MDL Number: MFCD00153951
PubChem CID: 23190
SMILES: C1=CN=C(C2=C1N(C=N2)C3C(C(C(O3)CO)O)O)N
InChi: InChI=1S/C11H14N4O4/c12-10-7-5(1-2-13-10)15(4-14-7)11-9(18)8(17)6(3-16)19-11/h1-2,4,6,8-9,11,16-18H,3H2,(H2,12,13)/t6-,8-,9-,11-/m1/s1
InChi Key: DBZQFUNLCALWDY-PNHWDRBUSA-N
