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Product Description
5-Fluoroorotic Acid (5-FOA) is used in yeast molecular genetics to detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) decarboxylase. 5-FOA is toxic to yeast cells that can synthesize the enzyme orotidine-5’-phosphate decarboxylase and are therefore unable to grow in 5-FOA-containing media.
5-Fluoroorotic Acid (5-FOA) is used in yeast molecular genetics to detect expression of the URA3 gene, which encodes orotine-5'-monophosphate (OMP) decarboxylase. 5-FOA is toxic to yeast cells that can synthesize the enzyme orotidine-5’-phosphate decarboxylase and are therefore unable to grow in 5-FOA-containing media.
Biovision | 2796 | 5-Fluoroorotic acid monohydrate (5-FOA) DataSheet
Alternate Name/Synonyms: 2,6-Dihydroxy-5-fluoropyrimidine-4-carboxylic acid; 5-Fluorouracil-4-carboxylic acid; 5-Fluorouracil-4-carboxylic acid hydrate
Appearance: Off-white to yellow solid
Formulation: N/A
CAS Number: 207291-81-4, 220141-70-8
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₅H₃FN₂O₄.H₂O
Molecular Weight: 192.1
Cell-Permeable?: No
Purity: ≥97% by titration
Solubilities: DMSO (>100 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A Yeast genetic counter-selection agent
MDL Number: MFCD00150658
PubChem CID: 16212749
SMILES: C1(=C(NC(=O)NC1=O)C(=O)O)F.O
InChi: InChI=1S/C5H3FN2O4.H2O/c6-1-2(4(10)11)7-5(12)8-3(1)9;/h(H,10,11)(H2,7,8,9,12);1H2
InChi Key: LODRRYMGPWQCTR-UHFFFAOYSA-N
