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Product Description
A non-selective, reversible and competitive inhibitor of NOS isoforms in vitro. The IC₅₀ values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.71, 0.78, and 5.8 µM, respectively. However, it shows good anti-nociceptive effects in vivo without affecting blood pressure via inhibition of eNOS.
7-Nitroindazole is a non-selective, reversible and competitive inhibitor of NOS isoforms in vitro. The IC₅₀ values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.71, 0.78, and 5.8 µM, respectively.
Biovision | 2360 | 7-Nitroindazole DataSheet
Alternate Name/Synonyms: 7-nitro-1H-indazole; 7-NI
Appearance: Brown solid
Formulation: N/A
CAS Number: 2942-42-9
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₇H₅N₃O₂
Molecular Weight: 163.13
Cell-Permeable?: Yes
Purity: ≥97% by GC
Solubilities: DMSO (~ 15 mg/ml) or EtOH (~4 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A non-selective, reversible and competitive inhibitor of NOS isoforms in vitro.
MDL Number: MFCD00022789
PubChem CID: 1893
SMILES: C1=CC2=C(C(=C1)[N+](=O)[O-])NN=C2
InChi: InChI=1S/C7H5N3O2/c11-10(12)6-3-1-2-5-4-8-9-7(5)6/h1-4H,(H,8,9)
InChi Key: PQCAUHUKTBHUSA-UHFFFAOYSA-N
