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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • PX-866

    Biovision | PX-866 | 1965

    Cell-permeable. A derivative of Wortmannin (Cat. No. 1670-1), that potently and irreversibly inhibits PI 3-kinase with selectivity for p110⍺ (IC₅₀ = 0.1 nM). Displays antitumor activity.PX-866 is a derivative of Wortmannin (Cat. No. 1670-1), that...

    €591 - €1,599
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  • PX-478 hydrochloride

    Biovision | PX-478 hydrochloride | B1033

    PX-478 hydrochloride is an inhibitor of HIF-1α (IC₅₀ of 20-30 μM) with potential antineoplastic activity. PX-478 inhibits HIF-1alpha protein levels and transactivation in a variety of cancer cell lines. The inhibitory effect of PX-478 on HIF-1alpha...

    €909 - €2,877
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  • PX 12

    Biovision | PX 12 | 2217

    PX-12 is an irreversible inhibitor of thioredoxin-1 (TRX-1) (Ki = 31 µM). It decreases the expression of HIF-1α, VEGF and iNOS (IC₅₀ values are 7.2, ~10 and 18.1 μM respectively). Also known to display antitumor activity and inhibits tubulin...

    €813 - €2,583
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  • Puromycin Dihydrochloride

    Biovision | Puromycin Dihydrochloride | 1860

    A nucleoside antibiotic. It inhibits protein synthesis by disrupting peptide transfer on ribosomes causing premature chain termination during translation. It is a potent translational inhibitor in both prokaryotic and eukaryotic cells. Resistance to...

    €591 - €5,874
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  • PU-H71

    Biovision | PU-H71 | 9649

    PU-H71 is a potent Heat Shock Protein 90 (Hsp90) inhibitor (IC₅₀ = 50 nM). Also inhibits cell growth in a range of breast cancer cell lines (IC₅₀ values are 17, 31, 65, 87 and 140 nM for SKBr3, MCF-7, MDA-MB-468, HCC-1806 and MDA-MB-231 cells...

    €813 - €2,484
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  • PTC-124

    Biovision | PTC-124 | 9421

    PTC-124 has been reported to help the ribosome skip over the premature stop, restore production of functional protein, and thereby potentially treat these genetic diseases. In a mouse model of cystic fibrosis caused by nonsense mutations, PTC-124...

    €666 - €1,893
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  • PT1

    Biovision | PT1 | B2035

    PT1 is an AMP-activated protein kinase (AMPK) activator. Stimulates AMPK heterotrimer (α1β1γ1) activity (EC = 0.3 μM). Selectively increases the activity of γ1- but not γ3-containing complexes. Directly activates AMPK by antagonizing autoinhibition.PT1...

    €1,209 - €3,933
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  • PSI-7977

    Biovision | PSI-7977 | 2715

    PSI-7977 is a phosphoramidate nucleotide prodrug for the treatment of hepatitis virus. It acts as a selective inhibitor of hepatitis C virus (HCV) NS5B polymerase.PSI-7977 is a phosphoramidate nucleotide prodrug for the treatment of hepatitis virus. It...

    €1,107 - €3,666
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  • Pseudolaric Acid B

    Biovision | Pseudolaric Acid B | 2512

    Pseudolaric acid B is a diterpene acid isolated from the bark of Pseudolarix kaempferi, that displays interesting antifungal, antifertility, and cytotoxic activity against multidrug resistant cell lines. Acts as PPARα signaling agonist as well as...

    €717 - €2,091
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  • PS48

    Biovision | PS48 | 1869

    An allosteric phosphoinositide-dependent protein kinase-1 (PDK1) activator (Kd = 10.3 μM). Binds exclusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site. It has recently been found that a combination of PS48, sodium butyrate...

    €642 - €4,350
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  • PS-341

    Biovision | PS-341 | 1846

    A potent (Ki = 0.6 nM), specific and reversible proteasome inhibitor. It inhibits cell proliferation of H460 cells (Human non-small cell lung cancer cell lines) with an IC₅₀ of 0.1 µM.PS-341 is a potent (Ki = 0.6 nM), specific and reversible proteasome...

    €615 - €1,452
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  • Prodigiosin

    Biovision | Prodigiosin | 2311

    Isolated from Serratia marcescens. Displays antibacterial, anticancer, cytotoxic, immunosuppressive, and antiproliferative activities. Prodigiosin induces apoptosis in hematopoietic cancer cells and cells derived from other human cancers, including...

    €717 - €1,995
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  • PRL-3 Inhibitor

    Biovision | PRL-3 Inhibitor | B1825

    P0108 is a potent inhibitor of phosphatase of regenerating liver-3 (PRL-3) (IC₅₀ = 0.9 μM). It reduces the invasive properties of mouse melanoma B16F10 cells in a cellular model. Sensitizes PRL-3-expressing cancer cells to chemotherapeutics. Inhibits...

    €717 - €2,091
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  • Pritelivir mesylate

    Biovision | Pritelivir mesylate | B2154

    Pritelivir is a potent helicase primase inhibitor. It inhibits replication of herpes simplex virus (HSV) type 1 and type 2 in the nanomolar range in vitro by abrogating the enzymatic activity of the viral primase-helicase complex. In various rodent...

    €717 - €2,091
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  • Prexasertib mesylate

    Biovision | Prexasertib mesylate | B2067

    Prexasertib is a potent inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity. Upon administration, prexasertib selectively binds to chk1, thereby preventing activity of chk1 and abrogating the repair of damaged DNA. This may...

    €960 - €3,072
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  • PQR-309

    Biovision | PQR-309 | B1300

    PQR-309 is a potent pan inhibitor of phosphoinositide-3-kinases (PI3K) and inhibitor of the mammalian target of rapamycin (mTOR), with potential antineoplastic activity. PQR-309 inhibits the PI3K kinase isoforms α, β, g and δ, and, to a lesser extent,...

    €909 - €2,877
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  • PPARγ Antagonist, G3335

    Biovision | PPARγ Antagonist, G3335 | 1979

    Cell-permeable. A dipeptide that acts as a selective and reversible PPARγ antagonist (KD ~ 8 µM). Shown to inhibit the agonist activity of Rosiglitazone (100 nM) in a dose-dependent manner (IC₅₀= 31.9 µM) in transfected COS-7 cells.PPARγ Antagonist,...

    €591 - €960
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  • PPACK II, trifluoroacetate

    Biovision | PPACK II, trifluoroacetate | B2151

    PPACKII is a specific and irreversible inhibitor of glandular and plasma kallikreins. Human tissue kallikreins (hKs) are a class of secreted serine proteases that involved in the release of vasodepressor peptides or kinins from a plasma substrate...

    €1,356 - €5,139
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  • PP3

    Biovision | PP3 | 1797

    A negative control for the Src family kinase inhibitor PP2 (Cat. No. 1767-1,5). Inhibits the activity of EGFR kinase at an IC₅₀ = 2.7 μM.PP3 is a negative control for the Src family kinase inhibitor PP2 (Cat. No. 1767-1,5). Inhibits the activity of EGFR...

    €591 - €1,554
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  • Ponasterone A

    Biovision | Ponasterone A | 2183

    A member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. An analog of ecdysone with similar properties to muristerone A. Induces expression of β-galactosidase to levels similar to those obtained with muristerone A induction. A reliable and...

    €642 - €1,701
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  • Polymyxin B sulfate

    Biovision | Polymyxin B sulfate | 2496

    Polymyxin B sulfate is a polypeptide antibiotic and is composed of polymyxins B1, B2, and B3 with fractions B1 and B2 comprising the majority of the mixture. Polymyxin B targets and alters permeability lipopolysaccharide (LPS) of gram negative bacteria...

    €864 - €2,142
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  • Podophyllotoxin

    Biovision | Podophyllotoxin | 2767

    Podophyllotoxin is a potent inhibitor of microtubule assembly and DNA topoisomerase II. Displays anticancer properties. Also antiviral and antihelminthic.Podophyllotoxin is a potent inhibitor of microtubule assembly and DNA topoisomerase II. Displays...

    €570 - €1,011
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  • PLX-7904

    Biovision | PLX-7904 | B1249

    PLX7904 is a potent and selective paradox-breaker RAF inhibitor. PLX7904 efficiently inhibits activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells. Importantly, it inhibits ERK1/2...

    €1,011 - €3,174
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  • PLX-4032

    Biovision | PLX-4032 | 2235

    Cell-permeable. A potent, selective and ATP-competitive, inhibitor of BRAF(V600E) kinase with potential antineoplastic activity. PLX-40432 selectively binds to the ATP-binding site of BRAF(V600E) kinase and inhibits its activity, which may result in an...

    €570 - €1,503
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  • PLX-3397

    Biovision | PLX-3397 | 9617

    PLX3397 is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity. PLX3397 binds to and inhibits phosphorylation of stem cell factor receptor (KIT), colony-stimulating factor-1 receptor...

    €813 - €2,190
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  • Pluronic® F-127

    Biovision | Pluronic® F-127 | 2730

    Pluronic® F-127 is a non-ionic detergent useful for isolation of membrane proteins. It has been found to facilitate the solubilization of water-insoluble dyes and other materials in physiological media.Pluronic® F-127 is a non-ionic detergent useful for...

    €666 - €1,476
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  • Plinabulin

    Biovision | Plinabulin | B2049

    Plinabulin (NPI-2358) is a vascular disrupting agent (VDA). Plinabulin binds to the colchicine binding site of β-tubulin preventing polymerization and disrupting the cytoplasmic microtubule network. It is also an antineoplastic agent that activates an...

    €813 - €2,484
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  • PKC412

    Biovision | PKC412 | 2052

    Cell-permeable. A derivative of Staurosporine (Cat. No. 1048) that inhibits a variety of serine/threonine and tyrosine kinases including protein kinase C (PKC) IC₅₀ = 50 nM), cyclic AMP-dependent protein kinase (PKA) (IC₅₀ = 2.4 µM), S6 kinase (IC₅₀ = 5...

    €888 - €2,730
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  • PK 11195

    Biovision | PK 11195 | 2054

    Cell-permeable. A Selective peripheral benzodiazepine antagonist. Enhances apoptosis and induces mitochondria cytochrome c release. Inhibits insulin secretion induced by glucose. Also displays anticancer activity.PK11195 is a selective peripheral...

    €591 - €1,575
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  • PJ-34 hydrochloride

    Biovision | PJ-34 hydrochloride | 2319

    A potent, water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor (EC₅₀ = 20 nM). Inhibits peroxynitrite-induced cell necrosis and displays significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides...

    €546 - €1,380
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  • Pixantrone maleate

    Biovision | Pixantrone maleate | 1958

    An analog of Mitoxantrone (Cat. No. 1885-50, 250) that displays antitumor properties with fewer toxic effects on cardiac tissue. Acts as a topoisomerase II poison and intercalating agent.Pixantrone maleate is an analog of Mitoxantrone (Cat. No. 1885-50,...

    €642 - €1,746
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  • Pitavastatin calcium

    Biovision | Pitavastatin calcium | B2090

    Pitavastatin calcium is a synthetic inhibitor of HMG-CoA (3-hydroxy-3-methylglutaryl-coenzyme A) reductase, (Ki = 1.7 nM). It lowers both total cholesterol and low density lipoprotein (LDL) cholesterol in animals and humans.Pitavastatin calcium is a...

    €615 - €1,701
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  • Piperlonguminine

    Biovision | Piperlonguminine | 1988

    Piperlonguminine is a known alkaloid amide from peppers, including Piper divaricatum. Acts as a potent anticancer agent. Displays inhibitory effect on alpha-melanocyte-stimulating hormone (alpha-MSH)-induced melanogenesis in melanoma B16 cells (IC₅₀= 9.6...

    €591 - €1,527
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  • PIK75

    Biovision | PIK75 | B1668

    PIK-75 is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM.PIK-75 is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than...

    €591 - €1,401
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  • PIK-293

    Biovision | PIK-293 | B1658

    PIK-293 is a PI3K inhibitor.PIK-293 is a PI3K inhibitor.Biovision | B1658 | PIK-293 DataSheetAlternate Name/Synonyms: PIK-293; PIK 293; PIK293; 2-[(4-amino-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl]-5-methyl-3-(2-methylphenyl)-4(3H)-quinazolinone;...

    €1,107 - €3,639
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  • Picropodophyllotoxin

    Biovision | Picropodophyllotoxin | 2765

    A potent and selective inhibitor of insulin-like growth factor 1 receptor (IGF1R) which is non-competitive with ATP. Displays no activity at IR, EGFR, FGFR or PDGFR. Inhibits IGF1R autophosphorylation IC₅₀ ~ 1 nM. Displays antiproliferative activity in...

    €666 - €1,893
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  • Pibrentasvir

    Biovision | Pibrentasvir | B2168

    Pibrentasvir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS5A inhibitor that targets the viral RNA replication and virion assembly.Pibrentasvir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS5A inhibitor that targets...

    €717 - €2,091
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  • PI3K-α Inhibitor

    Biovision | PI3K-α Inhibitor | B1869

    PI3Kα inhibitor is a potent and selective inhibitor of PI3Kα with IC₅₀ values of 2, 16, 660, and 220 nM for the α, β, γ, and 2Cβ isoforms, respectively. It inhibits PKA, KDR, PKCα, and cyclin E/Cdk2 significantly less effectively (IC₅₀ = 91, 3.4, 466,...

    €960 - €3,072
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  • PI3-Kɣ Inhibitor, AS-605240

    Biovision | PI3-Kɣ Inhibitor, AS-605240 | 1780

    Cell-permeable. A potent and selective inhibitor of PI 3-kinase γ (PI3Kγ) (IC₅₀ = 8 nM). Displays >33-fold selectivity over PI3Kδ and PI3Kβ and 7.5-fold selectivity over PI3Kα.AS-605240 is a potent and selective inhibitor of PI 3-kinase γ (PI3Kγ) (IC₅₀ =...

    €615 - €1,575
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  • SB1518 (Pacritinib)

    Biovision | SB1518 (Pacritinib) | 2450

    A potent JAK2/FLT3 inhibitor. Displays equipotent activity against JAK2 (I₅₀ = 23 nM) and FLT3 (IC₅₀ = 22 nM). SB1518 displays potent anti-proliferative effects on myeloid and lymphoid cell lines driven by mutant or wild-type JAK2 or FLT3, resulting from...

    €813 - €2,484
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  • Phleomycin

    Biovision | Phleomycin | 2724

    Phleomycin is an antibiotic produced by Streptomyces verticullus and is structurally related to Bleomycin. Used as a selective agent in transformation experiments with mammalian cells, plant cells and yeast. Its cytotoxic action results from its ability...

    €717 - €1,650
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  • PhiKan083

    Biovision | PhiKan083 | 9440

    PhiKan083 is a p53 stabilizing agent; preferentially binds mutated (Y220C) p53 over wild-type p53 at a site distinct from functional DNA/protein interaction regions. PhiKan083 slows rate of thermal denaturation of p53-Y220C.PhiKan083 is a p53 stabilizing...

    €1,062 - €3,321
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  • Phenformin hydrochloride

    Biovision | Phenformin hydrochloride | 1889

    An anti-diabetic drug of the biguanide class. Increases AMPK activity without increasing AMP/ATP. Also acts as a mitochondrial complex I inhibitor.Phenformin hydrochloride is an anti-diabetic drug of the biguanide class. Increases AMPK activity without...

    €546 - €1,650
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  • PHA-767491(HCl)

    Biovision | PHA-767491(HCl) | B1639

    PHA-767491 is a potent and selective ATP-competitive dual cdc7/cdk9 inhibitor.PHA-767491 is a potent and selective ATP-competitive dual cdc7/cdk9 inhibitor.Biovision | B1639 | PHA-767491(HCl) DataSheetAlternate Name/Synonyms: PHA-767491(HCl), CAY10572;...

    €642 - €1,725
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  • PF74

    Biovision | PF74 | B2369

    PF74 is a HIV-1 inhibitor that targets HIV capsid protein. PF74 binds specifically to HIV-1 particles and triggers premature HIV-1 uncoating in target cells. PF74 acts at an early stage of HIV-1 infection and inhibits reverse transcription in target...

    €813 - €2,484
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  • PF-562271 besylate

    Biovision | PF-562271 besylate | B1253

    F-562271 is an ATP-competitive, reversible inhibitor of FAK (IC₅₀ = 1.5 nM). It displays 10-fold reduced potency for PYK2 (IC₅₀ = 14 nM) and >100-fold selectivity against other protein kinases. PF-562271 inhibits FAK phosphorylation with an EC₅₀ value of...

    €909 - €2,877
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  • PF-477736

    Biovision | PF-477736 | B2335

    PF-477736 is a potent, ATP-competitive inhibitor of Chk1 (checkpoint kinase 1) (Ki =0.49 nM). It displays 100-fold selectivity over Chk2. PF-477736 abrogates DNA damage-induced cell cycle arrest.PF-477736 is a potent, ATP-competitive inhibitor of Chk1...

    €960 - €3,072
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