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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • PX-866

    Biovision | PX-866 | 1965

    Cell-permeable. A derivative of Wortmannin (Cat. No. 1670-1), that potently and irreversibly inhibits PI 3-kinase with selectivity for p110⍺ (IC₅₀ = 0.1 nM). Displays antitumor activity.PX-866 is a...

    £394 - £1,066
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  • PX 12

    Biovision | PX 12 | 2217

    PX-12 is an irreversible inhibitor of thioredoxin-1 (TRX-1) (Ki = 31 µM). It decreases the expression of HIF-1α, VEGF and iNOS (IC₅₀ values are 7.2, ~10 and 18.1 μM respectively). Also known to...

    £542 - £1,722
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  • PU-H71

    Biovision | PU-H71 | 9649

    PU-H71 is a potent Heat Shock Protein 90 (Hsp90) inhibitor (IC₅₀ = 50 nM). Also inhibits cell growth in a range of breast cancer cell lines (IC₅₀ values are 17, 31, 65, 87 and 140 nM for SKBr3,...

    £542 - £1,656
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  • PTC-124

    Biovision | PTC-124 | 9421

    PTC-124 has been reported to help the ribosome skip over the premature stop, restore production of functional protein, and thereby potentially treat these genetic diseases. In a mouse model of cystic...

    £444 - £1,262
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  • PT1

    Biovision | PT1 | B2035

    PT1 is an AMP-activated protein kinase (AMPK) activator. Stimulates AMPK heterotrimer (α1β1γ1) activity (EC = 0.3 μM). Selectively increases the activity of γ1- but not γ3-containing complexes...

    £806 - £2,622
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  • PSI-7977

    Biovision | PSI-7977 | 2715

    PSI-7977 is a phosphoramidate nucleotide prodrug for the treatment of hepatitis virus. It acts as a selective inhibitor of hepatitis C virus (HCV) NS5B polymerase.PSI-7977 is a phosphoramidate...

    £738 - £2,444
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  • PS48

    Biovision | PS48 | 1869

    An allosteric phosphoinositide-dependent protein kinase-1 (PDK1) activator (Kd = 10.3 μM). Binds exclusively to the PIF-binding pocket of PDK1, distinct from the ATP binding site. It has recently...

    £428 - £2,900
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  • PS-341

    Biovision | PS-341 | 1846

    A potent (Ki = 0.6 nM), specific and reversible proteasome inhibitor. It inhibits cell proliferation of H460 cells (Human non-small cell lung cancer cell lines) with an IC₅₀ of 0.1 µM.PS-341 is a...

    £410 - £968
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  • Prodigiosin

    Biovision | Prodigiosin | 2311

    Isolated from Serratia marcescens. Displays antibacterial, anticancer, cytotoxic, immunosuppressive, and antiproliferative activities. Prodigiosin induces apoptosis in hematopoietic cancer cells and...

    £478 - £1,330
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  • PRL-3 Inhibitor

    Biovision | PRL-3 Inhibitor | B1825

    P0108 is a potent inhibitor of phosphatase of regenerating liver-3 (PRL-3) (IC₅₀ = 0.9 μM). It reduces the invasive properties of mouse melanoma B16F10 cells in a cellular model. Sensitizes...

    £478 - £1,394
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  • PQR-309

    Biovision | PQR-309 | B1300

    PQR-309 is a potent pan inhibitor of phosphoinositide-3-kinases (PI3K) and inhibitor of the mammalian target of rapamycin (mTOR), with potential antineoplastic activity. PQR-309 inhibits the PI3K...

    £606 - £1,918
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  • PP3

    Biovision | PP3 | 1797

    A negative control for the Src family kinase inhibitor PP2 (Cat. No. 1767-1,5). Inhibits the activity of EGFR kinase at an IC₅₀ = 2.7 μM.PP3 is a negative control for the Src family kinase inhibitor...

    £394 - £1,036
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  • Ponasterone A

    Biovision | Ponasterone A | 2183

    A member of the ecdysteroid family. Ecdysone receptor (EcR) agonist. An analog of ecdysone with similar properties to muristerone A. Induces expression of β-galactosidase to levels similar to those...

    £428 - £1,134
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  • Podophyllotoxin

    Biovision | Podophyllotoxin | 2767

    Podophyllotoxin is a potent inhibitor of microtubule assembly and DNA topoisomerase II. Displays anticancer properties. Also antiviral and antihelminthic.Podophyllotoxin is a potent inhibitor of...

    £380 - £674
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  • PLX-7904

    Biovision | PLX-7904 | B1249

    PLX7904 is a potent and selective paradox-breaker RAF inhibitor. PLX7904 efficiently inhibits activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant...

    £674 - £2,116
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  • PLX-4032

    Biovision | PLX-4032 | 2235

    Cell-permeable. A potent, selective and ATP-competitive, inhibitor of BRAF(V600E) kinase with potential antineoplastic activity. PLX-40432 selectively binds to the ATP-binding site of BRAF(V600E)...

    £380 - £1,002
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  • PLX-3397

    Biovision | PLX-3397 | 9617

    PLX3397 is a small-molecule receptor tyrosine kinase (RTK) inhibitor of KIT, CSF1R and FLT3 with potential antineoplastic activity. PLX3397 binds to and inhibits phosphorylation of stem cell factor...

    £542 - £1,460
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  • Pluronic® F-127

    Biovision | Pluronic® F-127 | 2730

    Pluronic® F-127 is a non-ionic detergent useful for isolation of membrane proteins. It has been found to facilitate the solubilization of water-insoluble dyes and other materials in physiological...

    £444 - £984
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  • Plinabulin

    Biovision | Plinabulin | B2049

    Plinabulin (NPI-2358) is a vascular disrupting agent (VDA). Plinabulin binds to the colchicine binding site of β-tubulin preventing polymerization and disrupting the cytoplasmic microtubule network...

    £542 - £1,656
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  • PKC412

    Biovision | PKC412 | 2052

    Cell-permeable. A derivative of Staurosporine (Cat. No. 1048) that inhibits a variety of serine/threonine and tyrosine kinases including protein kinase C (PKC) IC₅₀ = 50 nM), cyclic AMP-dependent...

    £592 - £1,820
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  • PK 11195

    Biovision | PK 11195 | 2054

    Cell-permeable. A Selective peripheral benzodiazepine antagonist. Enhances apoptosis and induces mitochondria cytochrome c release. Inhibits insulin secretion induced by glucose. Also displays...

    £394 - £1,050
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  • PIK75

    Biovision | PIK75 | B1668

    PIK-75 is a p110α inhibitor with IC50 of 5.8 nM (200-fold more potently than p110β), isoform-specific mutants at Ser773, and also potently inhibits DNA-PK with IC50 of 2 nM.PIK-75 is a p110α...

    £394 - £934
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  • Pibrentasvir

    Biovision | Pibrentasvir | B2168

    Pibrentasvir is a direct acting antiviral agent and Hepatitis C virus (HCV) NS5A inhibitor that targets the viral RNA replication and virion assembly.Pibrentasvir is a direct acting antiviral agent...

    £478 - £1,394
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  • PI3K-α Inhibitor

    Biovision | PI3K-α Inhibitor | B1869

    PI3Kα inhibitor is a potent and selective inhibitor of PI3Kα with IC₅₀ values of 2, 16, 660, and 220 nM for the α, β, γ, and 2Cβ isoforms, respectively. It inhibits PKA, KDR, PKCα, and cyclin E/Cdk2...

    £640 - £2,048
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  • Phleomycin

    Biovision | Phleomycin | 2724

    Phleomycin is an antibiotic produced by Streptomyces verticullus and is structurally related to Bleomycin. Used as a selective agent in transformation experiments with mammalian cells, plant cells...

    £478 - £1,100
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  • PhiKan083

    Biovision | PhiKan083 | 9440

    PhiKan083 is a p53 stabilizing agent; preferentially binds mutated (Y220C) p53 over wild-type p53 at a site distinct from functional DNA/protein interaction regions. PhiKan083 slows rate of thermal...

    £708 - £2,214
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  • PF74

    Biovision | PF74 | B2369

    PF74 is a HIV-1 inhibitor that targets HIV capsid protein. PF74 binds specifically to HIV-1 particles and triggers premature HIV-1 uncoating in target cells. PF74 acts at an early stage of HIV-1...

    £542 - £1,656
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  • PF-477736

    Biovision | PF-477736 | B2335

    PF-477736 is a potent, ATP-competitive inhibitor of Chk1 (checkpoint kinase 1) (Ki =0.49 nM). It displays 100-fold selectivity over Chk2. PF-477736 abrogates DNA damage-induced cell cycle arrest...

    £640 - £2,048
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