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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • PF-431396

    Biovision | PF-431396 | 2844

    PF-431396 is dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor with IC₅₀ values 2 and 11 nM respectively.PF-431396 is dual focal adhesion kinase (FAK) and proline-rich tyrosine kinase 2 (PYK2) inhibitor with IC₅₀ values...

    £444 - £1,262
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  • PF299804

    Biovision | PF299804 | 2678

    PF299804 (Dacomitinib) is a potent, irreversible pan-HER inhibitor with IC₅₀’s of 6, 46, and 74 nM for ErbB1(HER1), ErbB2 (HER2), and ErbB4 (HER4), respectively. PF299804 inhibits ErbB1 autophosphorylation in A431 cells with an IC₅₀ of 15 nM.PF299804...

    £444 - £1,262
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  • PF-06650833

    Biovision | PF-06650833 | B1558

    PF-06650833 is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4).PF-06650833 is an inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4).Biovision | B1558 | PF-06650833 DataSheetAlternate Name/Synonyms:...

    £772 - £2,572
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  • PF-06463922

    Biovision | PF-06463922 | B1169

    PF-06463922 is a potent, selective, brain-penetrant, and high affinity ALK (Anaplastic lymphoma kinase) and ROS1 (c-Ros oncogene 1) inhibitor displaying >100-fold selectivity for ROS1 over panel of 204 other kinases. It has strong activity against all...

    £606 - £1,918
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  • PF-06409577

    Biovision | PF-06409577 | B2033

    PF-06409577 is a potent and selective allosteric activator of AMPK (EC₅₀ values are 7 and >40000 nM for AMPKα1β1γ1 and AMPKα1β2γ1, respectively). Displays minimal off-target effects on a panel of receptors, ion channels, PDEs and kinases. Shows efficacy...

    £772 - £2,444
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  • PF-05212384

    Biovision | PF-05212384 | 9461

    PF-05212384 is a potent, selective and ATP-competitive dual inhibitor of PI 3-kinase/mTOR (IC₅₀ values are 0.4, 1.6 and 5.4 nM for PI 3-Kα, mTOR and PI 3-Kγ respectively). Exhibits selectivity over 234 other protein kinases (IC₅₀ >10 μM). Potently...

    £708 - £2,296
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  • PF-04981517

    Biovision | PF-04981517 | 2917

    Potent and selective inhibitor of CYP3A (IC50 = 30 nM (CYP3A4), 17 μM (CYP3A5) and 70 μM (CYP3A7).Potent and selective inhibitor of CYP3A (IC50 = 30 nM (CYP3A4), 17 μM (CYP3A5) and 70 μM (CYP3A7).Biovision | 2917 | PF-04981517 DataSheetAlternate...

    £508 - £1,656
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  • PF-04554878

    Biovision | PF-04554878 | 2888

    PF-04554878 is potent, ATP-competitive, focal adhesion kinase (FAK) inhibitor with potential antiangiogenic and antineoplastic activities. PF-04554878 inhibits FAK phosphorylation at the Tyr397 site in a time- and dose-dependent manner. A combination of...

    £738 - £2,444
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  • PF-03394197

    Biovision | PF-03394197 | 2883

    PF-03394197 is potent and selective Janus kinase (JAK) inhibitor. It inhibits JAK family members with an IC₅₀ of 10-99 nM being most potent against JAK1 (IC₅₀ = 10 nM). PF-03394197 does not inhibit a panel of 38 non-JAK kinases (IC₅₀ >1 µM). Displays...

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  • Perifosine (KRX-0401)

    Biovision | Perifosine (KRX-0401) | 1592

    Belongs to an alkylphospholipid class of antineoplastic compounds that display potent antiproliferative activity in several in vitro and in vivo human tumor models. Perifosine induces apoptotic cell death in a variety of tumor cell lines. Apoptosis is...

    £836 - £2,214
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  • Pepstatin A

    Biovision | Pepstatin A | 1732

    An inhibitor of acid proteases (aspartyl peptidases), e.g. pepsin, rennin, and cathepsin D. The inhibitor is highly selective and does not inhibit thiol proteases, neutral proteases, or serine proteases .Pepstatin A is an inhibitor of acid proteases...

    £708 - £1,772
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  • Penicillin G sodium

    Biovision | Penicillin G sodium | 2503

    Penicillin G sodium is a member of the β-lactam antibiotics. β-Lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between...

    £508 - £1,542
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  • Penicillin G potassium, USP

    Biovision | Penicillin G potassium, USP | 2504

    Penicillin G potassium is a member of the β-lactam antibiotics. β-Lactams interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBP’s are enzymes which catalyze a pentaglycine crosslink between...

    £380 - £806
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  • Penicillide

    Biovision | Penicillide | B1245

    Penicillide is an inhibitor of Acyl-Coenzyme A cholesterol acyltransferase (ACAT), Calpain and Oxytocin receptor. It has shown to have growth inhibition properties in plants and displays anticancer, antibiotic and cytotoxic properties.Penicillide is an...

    £444 - £1,262
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  • Pellitorine

    Biovision | Pellitorine | 2053

    Cell-permeable. A natural product isolated from the roots of Piper Nigrum. Modulator of the sensory neuron function to induce tingling parethesia. Excellent stable model compound for sensory studies. α-Glucosidase inhibitor used in diabetes mellitus,...

    £508 - £1,508
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  • Pelitinib (EKB-569)

    Biovision | Pelitinib (EKB-569) | 2676

    Pelitinib is a pan-ErbB tyrosine kinase inhibitor with potential anticancer activity. Pelitinib irreversibly binds covalently to epidermal growth factor receptors (EGFR) ErbB-1, -2 and -4, thereby inhibiting receptor phosphorylation and signal...

    £410 - £1,134
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  • PD184352

    Biovision | PD184352 | 1585

    A highly potent ATP-noncompetitive MEK inhibitor. It inhibits MEK with an in vitro IC₅₀ of 1-1.3 nM. It does not inhibit other kinases. Highly recommended tool to inhibit MKK1 or MKK1 plus MKK5.PD184352 is a highly potent ATP-noncompetitive MEK inhibitor...

    £410 - £2,772
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  • PD-168393

    Biovision | PD-168393 | B2352

    PD-168393 is a cell-permeable, irreversible inhibitor of EGFR kinase activity (IC₅₀ = 0.70 nM). PD-168393 decreases the production of TNF-α and phosphorylation of ERK1/2 and p38 induced by LPS in cardiomyocytes.PD-168393 is a cell-permeable, irreversible...

    £444 - £1,262
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  • PD-166285 dihydrochloride

    Biovision | PD-166285 dihydrochloride | B2094

    PD-166285 is a potent, ATP-competitive and broadly active protein tyrosine kinase inhibitor. It inhibits tyrosine kinases c-Src, fibroblast growth factor receptor 1 (FGFR1), and platelet-derived growth factor receptor β(PDGFRβ) (IC₅₀ values are 8.4, 39.3...

    £606 - £1,918
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  • PD-146176

    Biovision | PD-146176 | B2313

    A specific, non-competitve 15-lipoxygenase (15-LOX) inhibitor (Ki = 197nM). Displays only weak effect on 5-LOX, 12-LOX, COX-1 or COX-2 (IC₅₀ = 0.54 μM for 15-LOX in rabbit reticulocytes).PD-146176 is a specific, non-competitve 15-lipoxygenase (15-LOX)...

    £640 - £2,048
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  • PD-123319 ditrifluoroacetate

    Biovision | PD-123319 ditrifluoroacetate | 9640

    PD-123319 is a potent, selective, non-peptide angiotensin AT2 receptor antagonist (IC₅₀ values are 34 and 210 nM in rat adrenal tissue and brain respectively). It has been used to selectively examine the specific roles for AT1R and AT2R in hypertensive...

    £606 - £1,918
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  • PD-1/PD-L1 Inhibitor 2

    Biovision | PD-1/PD-L1 Inhibitor 2 | B1050

    PD-1/PD-L1 Inhibitor 2 is a novel immunomodulator that prevents the interaction of PD-L1 with PD-1 (IC₅₀ = 18 nM).PD-1/PD-L1 Inhibitor 2 is a novel immunomodulator that prevents the interaction of PD-L1 with PD-1 (IC₅₀ = 18 nM).Biovision | B1050 |...

    £624 - £1,722
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  • PD-1/PD-L1 Inhibitor 1

    Biovision | PD-1/PD-L1 Inhibitor 1 | B1213

    PD1-PD-L1 inhibitor 1 (PD1-PD-L1-IN-1) is an inhibitor of the PD1-PD-L1 protein-protein interaction. Also acts as an immunomodulator. Programmed death ligand 1 (PD-L1) is a protein in humans that is encoded by the CD274 gene and the upregulation of PD-L1...

    £576 - £1,722
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  • PD-0332991 isethionate

    Biovision | PD-0332991 isethionate | 9480

    PD0332991 is a highly specific inhibitor of Cdk4 (IC₅₀ = 11 nM) and Cdk6 (IC₅₀ = 16 nM). Displays selectivity for Cdk4/6 over a panel of 34 additional protein kinases (IC₅₀ values are > 10 μM).PD0332991 is a highly specific inhibitor of Cdk4 (IC₅₀ = 11...

    £542 - £1,656
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  • PD0332991

    Biovision | PD0332991 | 2843

    PD0332991 is a highly specific inhibitor of Cdk4 (IC₅₀ = 11 nM) and Cdk6 (IC₅₀ = 16 nM). Displays selectivity for Cdk4/6 over a panel of 34 additional protein kinases (IC₅₀ values are > 10 μM).PD0332991 is a highly specific inhibitor of Cdk4 (IC₅₀ = 11...

    £478 - £1,394
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  • PD-0325901

    Biovision | PD-0325901 | 1643

    A selective and ATP non-competitive MEK inhibitor that suppresses the phosphorylation of ERK in murine colon 26 tumors (IC₅₀ = 0.33 nM). In combination with the GSK-3 inhibitor CHIR99021, prevents cell differentiation and sustains self-renewal of...

    £624 - £3,294
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  • PD 173074

    Biovision | PD 173074 | 1675

    A potent and selective FGFR1 tyrosine kinase inhibitor (IC₅₀ = 21.5 nM). Blocking of the FGFR signaling pathway by PD 173074 leads to self-renewal of stem cells via ERK1/2 activation. Treatment of FGF2-expressing human multipotent adipose-derived stem...

    £428 - £42,000
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  • PD 150,606

    Biovision | PD 150,606 | 1906

    Cell-permeable. A selective, non-competitive Calpain inhibitor (Ki = 210 nM and 370 nM for Calpain-1 and Calpain-2, respectively). Interacts with the calcium-binding domain of calpain.PD 150, 606 is a selective, non-competitive Calpain inhibitor (Ki =...

    £428 - £1,134
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  • PCI 34051

    Biovision | PCI 34051 | 2251

    PCI 34051 is a potent histone deacetylase 8 (HDAC8) inhibitor (IC₅₀ = 0.01 μM) with >200-fold selectivity over HDAC isoforms 1, 2, 3, 6, and 10 (IC₅₀s = 4, >50, >50, 2.9, and 13 μM, respectively).Cell-permeable. A potent histone deacetylase 8 (HDAC8)...

    £444 - £1,232
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  • PBTZ169

    Biovision | PBTZ169 | B1205

    PBTZ169 is a decaprenyl-phosphoribose-epimerase (DprE1) inhibitor. DprE1 is an an essential enzyme involved in the cell wall biosynthesis of Corynebacterineae.PBTZ169 is a decaprenyl-phosphoribose-epimerase (DprE1) inhibitor. DprE1 is an an essential...

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  • PBS-Tween® Tablets (1000 ml)

    Biovision | PBS-Tween® Tablets (1000 ml) | 2130

    PBS-Tween buffer contains the non-ionic detergent Tween® 20 which acts through blocking. It has the ability to reduce non-specific binding and protein-protein interaction during the wash step in protein and immunoassay procedures such as ELISA and...

    £542 - £2,198
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  • PBS Tablets (1000 ml)

    Biovision | PBS Tablets (1000 ml) | 2129

    One of the most commonly used buffers provided in a convenient, tablet form. PBS is isotonic and non-toxic to cells and has the ability to maintain their osmolarity thereby making the buffer suitable for washing procedures in cell cultures and for...

    £508 - £2,018
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  • Paromomycin Sulfate

    Biovision | Paromomycin Sulfate | B1528

    Paromomycin Sulfate is an aminoglycoside antibiotic that inhibits the initiation and elongation steps of protein synthesis by binding to 16S ribosomal RNA. Paramomycin binds to the A site, which causes defective polypeptide chains to be produced and...

    £346 - £772
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  • Pargyline hydrochloride

    Biovision | Pargyline hydrochloride | 2618

    A selective and irreversible monoamine oxidase –B (MAO-B) inhibitor. Pargyline is also a mechanism-based inhibitor of LSD1 that effectively inhibits histone demethylation in vivo.Pargyline is a selective and irreversible monoamine oxidase –B (MAO-B)...

    £380 - £542
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  • Parecoxib Sodium

    Biovision | Parecoxib Sodium | B1989

    Parecoxib sodium is an injectable prodrug of valdecoxib, that acts as a potent and selective inhibitor of cyclooxygenase-2 (COX-2). Useful for the short-term treatment of postoperative pain in adults. Parecoxib sodium is an injectable prodrug of...

    £444 - £1,232
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  • Papaverine hydrochloride

    Biovision | Papaverine hydrochloride | B2315

    An opium alkaloid that acts as a phosphodiesterase inhibitor (IC₅₀ = 13 μM). It increases cellular cAMP levels and alters cellular function. It has been shown to reduce arterial and cerebral vasospasm and has been used to treat erectile dysfunction...

    £380 - £806
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  • PAP-AMC, Tyrosinase substrate

    Biovision | PAP-AMC, Tyrosinase substrate | 2858

    A useful fluorogenic substrate for tyrosinase. When assaying in phosphate buffer at pH 7.1, the optimal excitation/emission wavelengths are 340/440 nm.A useful fluorogenic substrate for tyrosinase. When assaying in phosphate buffer at pH 7.1, the optimal...

    £1,066 - £3,278
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  • Panobinostat (LBH589)

    Biovision | Panobinostat (LBH589) | 1612

    Panobinostat (LBH589) is a highly potent inhibitor of both histone deacetylase 1 (HDAC1) activity and tumour cell proliferation in vitro. The IC₅₀ values of HDAC isozymes HDAC1-IP Ac-H4, HDAC8, MALunselective, B61HDAC1 and B12HDAC6 are 0.23±0.06, 283±29,...

    £526 - £3,588
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  • Pamidronate disodium

    Biovision | Pamidronate disodium | 1884

    A bisphosphonate compound that inhibits bone resorption, the natural, ongoing process of bone being destroyed by osteoclasts. Also inhibits farnesyl diphosphate synthase (IC₅₀ = 200 nM).Pamidronate disodium is a bisphosphonate compound that inhibits bone...

    £428 - £1,180
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  • P529

    Biovision | P529 | 2462

    A potent PI3K/Akt/mTOR inhibitor that inhibits the TORC1 and TORC2 complexes. Displays inhibition of both Akt signaling and mTOR signaling similarly in tumor and vasculature. P529 inhibits tumor growth, angiogenesis and vascular permeability.P529 is a...

    £576 - £1,754
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  • P5091

    Biovision | P5091 | 2277

    Cell-permeable. A Selective inhibitor of the ubiquitin-specific protease USP7 (IC₅₀ = 4.2 µM). Induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance. Displays antiangiogenic activity in vivo.P5091 is a selective inhibitor of the...

    £410 - £1,134
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  • P505-15 hydrochloride

    Biovision | P505-15 hydrochloride | 9583

    P505-15 is a potent, cell-permeable, highly selective, small molecule SYK inhibitor (IC₅₀ = 1 nM) with anti-SYK activity that is at least 80-fold greater than its affinity for other kinases. P505-15 blocks B cell receptor-mediated cell signaling and...

    £708 - £2,116
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  • Oxytetracycline Hydrochloride

    Biovision | Oxytetracycline Hydrochloride | B1527

    Oxytetracycline is a tetracycline analog isolated from the actinomycete Streptomyces rimosus. It is an antibiotic used for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis,...

    £346 - £708
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  • OXA-01

    Biovision | OXA-01 | 2695

    OXA-01 is an ATP-competitive, selective dual inhibitor of mTORC1/mTORC2. Displays antiangiogenic and antitumor properties.OXA-01 is an ATP-competitive, selective dual inhibitor of mTORC1/mTORC2. Displays antiangiogenic and antitumor properties.Biovision...

    £576 - £1,788
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  • Ouabain

    Biovision | Ouabain | B2068

    Ouabain is a cardioactive glycoside consisting of rhamnose and ouabagenin, obtained from the seeds of Strophanthus gratus and other plants of the Apocynaceae. Acts as a potent and selective Na⁺/K⁺ ATPase inhibitor.Ouabain is a cardioactive glycoside...

    £410 - £1,002
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  • OTX015

    Biovision | OTX015 | 2651

    OTX015 is a potent inhibitor of BRD2, BRD3, and BRD4 (EC₅₀s = 10-19 nM). It displays antiproliferative effects at a sub-micromolar range in vitro in a wide range of solid tumor types and leukemias, downregulating c-Myc expression and inducing cell cycle...

    £542 - £1,656
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  • OSU-03012

    Biovision | OSU-03012 | 2295

    A novel celecoxib derivative, that acts as a potent inhibitor of 3-phosphoinositide-dependent kinase-1 (PDK1) activity (IC₅₀ = 5 µM for recombinant PDK1). It displays anti-cancer activity in a COX-2-independent manner via inhibition of the phosphatidyl...

    £444 - £1,262
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