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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • GSK-1940029

    Biovision | GSK-1940029 | B2373

    GSK-1940029 is a potent stearoyl-coA desaturase (SCD) inhibitorGSK-1940029 is a potent stearoyl-coA desaturase (SCD) inhibitorBiovision | B2373 | GSK-1940029 DataSheetAlternate Name/Synonyms:...

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  • GSK1349572

    Biovision | GSK1349572 | 2288

    A potent, second generation HIV integrase inhibitor (IC₅₀ = 2.7 nM) that displays potent antiviral activity.GSK1349572 is a potent, second generation HIV integrase inhibitor (IC₅₀ = 2.7 nM) that displays potent antiviral activity.Biovision | 2288 |...

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  • GSK1325756

    Biovision | GSK1325756 | B1103

    GSK1325756 is a selective and reversible CXCR2 antagonist with IC₅₀ value of 12.5 nM. GSK1325756 displays anti-inflammatory effects in various preclinical and clinical models.GSK1325756 is a selective and reversible CXCR2 antagonist with IC₅₀ value of 12...

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  • GSK-1292263

    Biovision | GSK-1292263 | B1556

    GSK-1292263 is a novel GPR119 receptor agonist and is used for the treatment of type 2 diabetes. GSK1292263 improves glucose regulation in animal models of diabetes, but has no effect on plasma glucose in type 2 diabetics.GSK-1292263 is a novel GPR119...

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  • GSK1278863

    Biovision | GSK1278863 | B1107

    GSK-1278863 is a novel Hypoxia-Inducible Factor-Prolyl Hydroxylase Inhibitor (HIF-PHI). Hypoxia-inducible factor−prolyl hydroxylase inhibitors stimulate endogenous EPO synthesis and induce effective erythropoiesis by non-EPO effects.GSK-1278863 is a...

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  • GSK-121 trifluoroacetate

    Biovision | GSK-121 trifluoroacetate | B1034

    GSK-121 is a novel protein arginine deiminase 4 (PAD4) inhibitor. GSK-121 was shown to inhibit the citrullination of PAD4 target proteins in a functional assay with an IC₅₀ value of 3.2 µM.GSK-121 is a novel protein arginine deiminase 4 (PAD4) inhibitor...

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  • GSK-1120212

    Biovision | GSK-1120212 | 1960

    A potent and selective allosteric inhibitor of the MEK1 (IC₅₀ = 0.7 nM) and MEK2 (IC₅₀ = 0.9 nM) enzymes with potential antineoplastic activity.GSK-1120212 is a potent and selective allosteric inhibitor of the MEK1 (IC₅₀ = 0.7 nM) and MEK2 (IC₅₀ = 0.9...

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  • GSK-106 hydrochloride

    Biovision | GSK-106 hydrochloride | B1036

    GSK-106 is a useful negative control for PAD4 inhibitors (GSK-121 and GSK-484). It does not inhibit PAD4 nor does it prevent the citrullination of PAD4 target proteins or the formation of neutrophil extracellular traps in mouse or human neutrophils...

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  • GSK-1059615

    Biovision | GSK-1059615 | 9450

    GSK-1059615 is a potent, reversible, ATP-competitive inhibitor of PI3Kα (IC₅₀ = 2 nM). It inhibits proliferation in BT474 cells and attenuates MAPK signaling.GSK-1059615 is a potent, reversible, ATP-competitive inhibitor of PI3Kα (IC₅₀ = 2 nM). It...

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  • GSK-0660

    Biovision | GSK-0660 | 2897

    GSK-0660 is a selective PPARδ antagonist (IC₅₀ values are 0.155, > 10 and ≥ 10 μM at PPARδ, PPARα and PPARγ, respectively).GSK-0660 is a selective PPARδ antagonist (IC₅₀ values are 0.155, > 10 and ≥ 10 μM at PPARδ, PPARα and PPARγ, respectively)...

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  • GS-9973

    Biovision | GS-9973 | 2669

    GS-9973 is a potent and highly selective Syk (spleen tyrosine kinase) inhibitor (IC₅₀ = 7.7 nM).GS-9973 is a potent and highly selective Syk (spleen tyrosine kinase) inhibitor (IC₅₀ = 7.7 nM).Biovision | 2669 | GS-9973 DataSheetAlternate Name/Synonyms:...

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  • Grazoprevir (MK-5172)

    Biovision | Grazoprevir (MK-5172) | B2337

    Grazoprevir is a direct acting antiviral medication used as part of combination therapy to treat chronic Hepatitis C, an infectious liver disease caused by infection with Hepatitis C Virus (HCV). Grazoprevir is a second-generation hepatitis C virus...

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  • GPNA (monohydrate)

    Biovision | GPNA (monohydrate) | B2150

    GPNA is a substrate for γ-glutamyl transpeptidase. GPNA has also been shown to be an inhibitor of glutamine uptake - solute-linked carrier family A1 member 5 (SLC1A5). Cellular uptake of L-glutamine (regulated by SLC1A5) is a rate-limiting step that...

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  • Gossypin

    Biovision | Gossypin | 2374

    A glucoside occurring in cotton and Hubiscus flowers that acts as a potent antimelanoma agent. Gossypin inhibits human melanoma cell proliferation, in vitro, in melanoma cell lines that harbors both BRAF-V600E kinase and CDK4 as well as in cells with...

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  • GNE 477

    Biovision | GNE 477 | B1657

    GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI3Kα, Kiapp is 21 nM for mTOR.GNE-477 is a potent and efficacious dual PI3K/mTOR inhibitor with IC50 of 4 nM for PI3Kα, Kiapp is 21 nM for mTOR.Biovision | B1657 | GNE...

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  • GN25

    Biovision | GN25 | 9430

    GN25 blocks Snail binding to p53 and induces p53 expression in cancer cells in a KRas dependent manner. Oncogenic KRas has been shown to inhibit p53 function by inducing Snail to bind and eliminate p53 through exocytosis. At 10 μM, GN25 significantly...

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  • GLX-351322

    Biovision | GLX-351322 | B2340

    GLX-351322 is a potent NADPH oxidase-4 (NOX-4) inhibitor. Displays selectivity for NOX-4 over NOX-2. GLX-351322 inhibits hydrogen peroxide production from tetracycline inducible NOX4-overexpressing cells (IC₅₀ = 5 µM).GLX-351322 is a potent NADPH...

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  • Glutathione ethyl ester

    Biovision | Glutathione ethyl ester | B2307

    Glutathione (GSH) ethyl ester is a cell-permeable derivative of GSH that undergoes hydrolysis by intracellular esterases to release GSH. Effective transport of GSH ethyl ester has been used to protect cells against damage from radiation, oxidants, and...

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  • Glutaminase C-IN-1 (968)

    Biovision | Glutaminase C-IN-1 (968) | B1198

    Glutaminase C-IN-1 (968) a cell-permeable, reversible inhibitor of a mitochrondrial glutaminase splice variant, glutaminase C (IC₅₀ = ~2.5 µM), which is commonly found in cancer cells. Glutaminase C-IN-1 (968) blocks transformation induced by Rho GTPases...

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  • GLPG-1690

    Biovision | GLPG-1690 | B1850

    GLPG-1690 is a selective autotaxin inhibitor with potential application in idiopathic pulmonary disease (IPF).GLPG-1690 is a selective autotaxin inhibitor with potential application in idiopathic pulmonary disease (IPF).Biovision | B1850 | GLPG-1690...

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  • Globosuxanthone A

    Biovision | Globosuxanthone A | B2130

    Globosuxanthone A is a dihydroxyxanthenone isolated from Chaetomium globosum. It displays activity against several solid tumor cell lines, NCI-H460, MCF-7, SF-268, PC-3, PC-3M, LNCaP, and DU-145.Globosuxanthone A is a dihydroxyxanthenone isolated from...

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  • GKT-137831

    Biovision | GKT-137831 | 9444

    GKT-137831 is a novel pyrazolopyridinedione derivative that acts as a Nox4 and Nox1 inhibitor ((Ki 100–150 nM). GKT-137831 attenuates hypoxia-induced pulmonary vascular cell proliferation. Also a potent inhibitor of fibrosis and hepatocyte apoptosis...

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  • GJ-103 Sodium salt

    Biovision | GJ-103 Sodium salt | B1842

    GJ103 sodium salt is an active, water-soluble analog of the read-through compound GJ072. Chemical-induced read through of premature stop codons might be exploited as a potential treatment strategy for genetic disorders caused by nonsense mutations. It...

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  • Givinostat hydrochloride

    Biovision | Givinostat hydrochloride | B2081

    Givinostat is a potent hydroxymate inhibitor of histone deacetylase (HDAC) with potential anti-inflammatory, anti-angiogenic, and antineoplastic activities. Givinostat inhibits class I and class II HDACs, resulting in an accumulation of highly acetylated...

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  • Gibberellic acid

    Biovision | Gibberellic acid | B2234

    Gibberellic acid (GA) is a tetracyclic di-terpenoid and a plant hormone that stimulates plant growth and development. It stimulates seed germination, triggers transitions from meristem to shoot growth, juvenile to adult leaf stage, vegetative to...

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  • GFT505

    Biovision | GFT505 | B1030

    GFT505 (Elafibranor) is a novel liver-targeted peroxisome proliferator-activated receptor alpha/delta (PPARα/δ) agonist. Displays anti-diabetic effects in db/db mice.GFT505 (Elafibranor) is a novel liver-targeted peroxisome proliferator-activated...

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  • Geodin

    Biovision | Geodin | 9685

    Geodin is a Plasmigen activator inhibitor (PAI-1) inhibitor and Glucose uptake stimulator.Geodin is a Plasmigen activator inhibitor (PAI-1) inhibitor and Glucose uptake stimulator.Biovision | 9685 | Geodin DataSheetAlternate Name/Synonyms: Methyl...

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  • Gentamicin sulfate

    Biovision | Gentamicin sulfate | B1270

    Gentamicin sulfate, a broad-spectrum aminoglycoside antibiotic, used as a selection agent (gentamicin-resistance gene) in cell culture and molecular biology applications. Gentamicin causes codon misreading by binding to the 30S ribosomal subunit,...

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  • Gemcitabine Hydrochloride

    Biovision | Gemcitabine Hydrochloride | 1759

    A nucleoside analog of deoxycytidine used in chemotherapy to treat various types of cancer. Gemcitabine is converted intracellularly to the active metabolites difluorodeoxycytidine di- and triphosphate (dFdCDP, dFdCTP). dFdCDP inhibits ribonucleotide...

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  • GDC0994

    Biovision | GDC0994 | B1629

    GDC-0994 is highly selective inhibitor of extracellular signal-regulated kinase (ERK), ERK1 and ERK2, with biochemical potency of 1.1 nM and 0.3 nM, respectively.GDC-0994 is highly selective inhibitor of extracellular signal-regulated kinase (ERK), ERK1...

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  • GDC-0980

    Biovision | GDC-0980 | 2668

    GDC-0980, a selective, potent, orally bioavailable inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2). It inhibits PI3Kα/β/δ/γ with IC₅₀ values of 5 nM/27 nM/7 nM/14 nM, respectively and mTOR with Ki of 17 nM. GDC-0980 is highly selective versus...

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  • GDC-0941 Dimethanesulfonate

    Biovision | GDC-0941 Dimethanesulfonate | 9618

    GDC-0941 is a potent, selective, inhibitor of pan-class I PI3 kinase (PI3K), with IC₅₀ values of 3, 33, 3, 75, 1230 and 580 nM for p110 α, β, δ and γ isoforms, DNA-PK and mTOR respectively. Displays antineoplastic activity.GDC-0941 is a potent,...

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  • GDC-0941

    Biovision | GDC-0941 | 1623

    GDC-0941 is a potent inhibitor of p110α and p110δ (IC₅₀ = 3 nM). It selectively binds to PI3K isoforms in an ATP-competitive manner, inhibiting the production of the secondary messenger phosphatidylinositol-3,4,5-trisphosphate (PIP3) and activation of...

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  • GDC-0917

    Biovision | GDC-0917 | B1918

    GDC-0917 (CUDC-427) is a second mitochondrial activator of caspases (Smac) mimetic, a small molecule inhibitor, that mimics Smac, an endogenous antagonist of IAP proteins. GDC-0917 binds to the Smac binding groove on IAPs, including the direct caspase...

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  • GDC0879

    Biovision | GDC0879 | B1340

    A novel, potent, and selective inhibitor of B-Raf with an IC50 value of 0.13 nMA novel, potent, and selective inhibitor of B-Raf with an IC50 value of 0.13 nMBiovision | B1340 | GDC0879 DataSheetAlternate Name/Synonyms:...

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  • GDC-0853

    Biovision | GDC-0853 | B2074

    GDC-0853 is a potent and selective, Bruton's tyrosine kinase (BTK) inhibitor with potential antineoplastic activity. GDC-0853 suppresses B cell- and myeloid cell-mediated components of disease and demonstrates dose-dependent activity in an in vivo rat...

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  • GDC-0449

    Biovision | GDC-0449 | 1890

    A potent inhibitor of Smoothened (SMO), a key mediator of Hedgehog (Hh) signaling pathway. Inhibition of SMO renders the transcription factor GLI inactive, thus preventing the expression of genes that mediate the role of Hh on tumor growth.GDC-0449 is a...

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  • GDC-0068

    Biovision | GDC-0068 | 2667

    GDC-0068 is a potent, ATP-competitive, pan-Akt inhibitor with IC₅₀s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively. Displays selectivity over more than other 200 screened kinases. Potential anticancer agent.GDC-0068 is a potent, ATP-competitive,...

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  • GDC-0032

    Biovision | GDC-0032 | 9573

    GDC-0032 is a potent, and selective inhibitor of Class I PI3-K α, δ, and γ isoforms, with 30-fold less inhibition of the PI3K β isoform relative to the PI3K α isoform. This next generation PI3-K inhibitor displays increased anti-tumor activity against...

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  • GBR-12935

    Biovision | GBR-12935 | B1998

    GBR-12935 is a potent and selective dopamine reuptake inhibitor.GBR-12935 is a potent and selective dopamine reuptake inhibitor.Biovision | B1998 | GBR-12935 DataSheetAlternate Name/Synonyms: 1-(2...

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  • Gardiquimod

    Biovision | Gardiquimod | 2002

    A selective ligand for human or mouse Toll-like receptor 7 (TLR7). Induces the activation of NF-κB in HEK 293 cells expressing TLR7. Activates TLR8 only at high concentrations (3µg/ml). Gardiquimod is more active than Imiquimod (Cat. No. 1698-100)...

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  • GANT61

    Biovision | GANT61 | 1892

    Cell-permeable. A Hedgehog (Hh) signaling pathway antagonist. Inhibits Hh signaling downstream of Smo and Sufu at the level of Gli (IC₅₀ = 5 µM). GANT61 has also been shown to inhibit the in vitro proliferation of PANC1 and 22Rv1 cells which have...

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  • GANT58

    Biovision | GANT58 | 1812

    Cell-permeable. Acts as a blocker of Hedgehog (Hh) pathway downstream of SMO and SUFU causing Gli1 nuclear accumulation. It also targets Gli-mediated gene transactivation (IC₅₀ ~ 5 µM in SAG-stimulated Shh-L2 cells) and displays anti-proliferative and...

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  • Ganetespib (STA-9090)

    Biovision | Ganetespib (STA-9090) | 9459

    Ganetespib (STA-9090) is a non-Geldanamycin, selective Hsp90 inhibitor that displays antineoplastic activity. downregulates VEGFR, c-MET, HER2, IGF-IR, EGFR, and other Hsp90 client proteins involved in hepatocarcinogenesis, thereby making it an...

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  • Galloflavin

    Biovision | Galloflavin | 2672

    Galloflavin is a lactate dehydrogenase (LDH) inhibitor inhibiting both LDH-A and LDH-B isoforms of the enzyme with Ki values of 5.46 a µM and 15.06 µM, respectively. It blocks the proliferation of cancer cells by blocking glycolysis and ATP production...

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  • Galiellactone

    Biovision | Galiellactone | 2623

    Galiellalactone is a fungal metabolite that inhibits IL-6-mediated JAK/STAT signal transduction in HepG2 cells (IC₅₀ = 0.25-0.5 μM). The selectivity of this compound is achieved by its ability to block the binding of activated STAT3 dimers to their DNA...

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  • Fusidic acid

    Biovision | Fusidic acid | B2392

    Fusidic Acid is a bacteriostatic antibiotic derived from the fungus Fusidium coccineum that acts as a bacterial protein synthesis inhibitor by preventing the turnover of elongation factor G (EF-G) from the ribosome. Fusidic acid is effective primarily on...

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  • Fusicoccin

    Biovision | Fusicoccin | B1625

    Fusicoccin is a toxin originally extracted from Fusicoccum amygdali DelFusicoccin is a toxin originally extracted from Fusicoccum amygdali DelBiovision | B1625 | Fusicoccin DataSheetAlternate Name/Synonyms: Fusicoccin,...

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  • FURA-5F/AM

    Biovision | FURA-5F/AM | 9551

    FURA-5F/AM is a fluorescent cell membrane-permeant form of FURA-2 (Cat. No. 2243) that can be loaded into the cell where it is hydrolysed by cytosolic esterases and trapped as the active chelator. . lmax: 370± 3 nm (EtOAc); lem: 477± 4 nm (EtOAc)...

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  • FURA-4F/AM

    Biovision | FURA-4F/AM | 9550

    Fura-4F AM is a fluorescent intracellular ratiometric calcium indicator analog of FURA-2 (Cat. No. 2243) for detection of higher Ca²⁺ concentrations. lmax: 370± 3 nm (EtOAc); lem: 475± 4 nm (EtOAc).Fura-4F AM is a fluorescent intracellular ratiometric...

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  • Fucoxanthine

    Biovision | Fucoxanthine | B2072

    Fucoxanthin is a natural pigment found in microalgae, especially diatoms and Chrysophyta. Recently, it has been shown to have antioxidant, anti-inflammatory, anti-tumor, and anti-obesity activity in humans. Fucoxanthin increases the amount of...

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  • FR180204

    Biovision | FR180204 | B1683

    FR180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2 with Ki value of 0.31 uM and 0.14 uM respectively; has IC50 values of 0.51 and 0.33 μM in enzymatic assays against ERK1 and ERK2, respectively.FR180204 is a potent and...

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