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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • mTOR Inhibitor, WYE-132

    Biovision | mTOR Inhibitor, WYE-132 | 2256

    Cell-permeable. A potent, selective, and ATP-competitive mTOR (mammalian Target Of Rapamycin) inhibitor (IC₅₀ = 0.19 nM). Displays >5000-fold selectivity over PI3Ks. WYE-132 inhibits mTORC1 and mTORC2 in diverse cancer models in vitro and in vivo.Wye-132...

    €591 - €789
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  • mTOR Inhibitor, Ku-0063794

    Biovision | mTOR Inhibitor, Ku-0063794 | 1779

    A potent mTOR (mammalian target of rapamycin) inhibitor (IC₅₀ = ~10 nM for mTORC1 and mTORC2, respectively). Displays no activity against PI 3-kinase or 76 other kinases tested.Ku-0063794 is a potent mTOR (mammalian target of rapamycin) inhibitor (IC₅₀ =...

    €693 - €1,917
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  • MSX-130

    Biovision | MSX-130 | B2157

    MSX-130 is CXCR4 AntagonistMSX-130 is CXCR4 AntagonistBiovision | B2157 | MSX-130 DataSheetAlternate Name/Synonyms: 2,2'-(1,4-Phenylene)bis[4,5-diphenyl-1H-imidazole]Appearance: Cystalline solidFormulation: N/ACAS Number: 4051-59-6Structure Available?:...

    €909 - €2,877
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  • MSC-2530818

    Biovision | MSC-2530818 | B1975

    MSC-2530818 is a potent, selective CDK8 Inhibitor (IC₅₀ = 2.6 nM). It displays potent inhibition of phospho-STAT1SER727, an established biomarker of CDK8 activity. MSC2530818 demonstrates potent inhibition of WNT-dependent transcription in human cancer...

    €717 - €2,091
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  • MS-275 (Entinostat, SNDX-275)

    Biovision | MS-275 (Entinostat, SNDX-275) | 1590

    Preferentially inhibits HDAC1 (IC₅₀ = 300 nM) over HDAC3 (IC₅₀ = 8 µM). Has no inhibitory activity towards HDAC8 (IC₅₀>100 µM).MS-275 (Entinostat, SNDX-275) preferentially inhibits HDAC1 (IC₅₀ = 300 nM) over HDAC3 (IC₅₀ = 8 µM). Has no inhibitory...

    €1,821 - €4,746
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  • MRL-24

    Biovision | MRL-24 | 2764

    Cell-permeable. MRL-24 displays high affinity for PPARγ with excellent anti-diabetic activity in mice but poor PPARγ agonist activity in transcription and adipogenesis assays. Highly effective (30 nM) at blocking Cdk5-mediated phosphorylation of PPARγ...

    €615 - €1,554
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  • MPEP hydrochloride

    Biovision | MPEP hydrochloride | B1151

    MPEP hydrochloride is a highly selective and potent non-competitive antagonist at the mGlu5 (metabotropic glutamate receptor subtype 5) receptor subtype (IC₅₀ = 36 nM). It is a positive allosteric modulator at mGlu4. MPEP hydrochloride reduces DHPG (S-3,...

    €864 - €2,682
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  • MOZ-IN-3

    Biovision | MOZ-IN-3 | B2245

    MOZ-IN-3 is a potent inhibitor of MOZ, a member of histone acetyltransferases (IC₅₀ = 55 nM).MOZ-IN-3 is a potent inhibitor of MOZ, a member of histone acetyltransferases (IC₅₀ = 55 nM).Biovision | B2245 | MOZ-IN-3 DataSheetAlternate Name/Synonyms:...

    €960 - €3,072
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  • MoTP

    Biovision | MoTP | 1852

    A useful tool for elucidating melanocyte stem cell regeneration, recruitment and maintenance mechanisms. Specifically ablates zebrafish larval melanocytes or melanoblasts, and this melanocytotoxicity is dependent on tyrosinase activity.MoTP is a useful...

    €642 - €1,452
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  • Motesanib diphosphate

    Biovision | Motesanib diphosphate | B2196

    Motesanib (AMG-706), is an orally bioavailable multiple-receptor tyrosine kinase inhibitor with potential antineoplastic activity. Motesanib selectively targets and inhibits vascular endothelial growth factor (VEGFR), platelet-derived growth factor...

    €717 - €2,091
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  • Monensin Methyl Ester

    Biovision | Monensin Methyl Ester | 1808

    A polyether ionophore antibiotic. Widely used in ion selective electrodes.Monensin Methyl Ester is a polyether ionophore antibiotic. Widely used in ion selective electrodes.Biovision | 1808 | Monensin Methyl Ester DataSheetAlternate Name/Synonyms: Methyl...

    €693 - €2,043
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  • Monensin A Sodium

    Biovision | Monensin A Sodium | B1623

    Sodium Monensin, isolated from Streptomyces cinnamonensis, is a well-known representative of naturally polyether ionophore antibiotics. It preferentially forms complexes with monovalent cations to enable transport across lipid membranes.Sodium Monensin,...

    €615 - €2,337
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  • Moexipril hydrochloride

    Biovision | Moexipril hydrochloride | B2134

    Moexipril is a prodrug of the long-acting angiotensin converting enzyme (ACE) inhibitor moexiprilat (IC₅₀s = 2.1 nM and 2.7 µM for moexiprilat and moexipril, respectively). In addition to its antihypertensive activity, moexipril has been identified as a...

    €615 - €1,356
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  • MnTMPyP Pentachloride

    Biovision | MnTMPyP Pentachloride | 2056

    A cell-permeable superoxide dismutase (SOD) mimetic and a peroxynitrite scavenger as well as an oxidative stress inhibitor. Displays protective effect against H₂O₂-mediated injury. Also displays neuroprotective properties.MnTMPyP Pentachloride is a...

    €570 - €1,158
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  • MnTBAP Chloride

    Biovision | MnTBAP Chloride | 2058

    A cell-permeable superoxide dismutase (SOD) mimetic and potent inhibitor of peroxynitrite-induced oxidative reactions (peroxynitrite scavenger), but not a scavenger of nitric oxide (NO). Protects T cells from superoxide generation, caspase-dependent DNA...

    €570 - €1,158
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  • MN64

    Biovision | MN64 | B1127

    MN64 is a potent and selective tankyrase (TNKS) inhibitor (IC₅₀ values of 6 and 72 nM for TNKS1 and TNKS2 respectively). It has no effect on PARP-1 or PARP-2 (IC₅₀ > 19 µM). Through its effects on TNKS, MN-64 inhibits signaling along the Wnt/β-catenin...

    €864 - €2,682
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  • MMP-III Inhibitor, NNGH

    Biovision | MMP-III Inhibitor, NNGH | 2569

    Cell-permeable. A potent inhibitor of matrix metalloproteinase-3 (MMP-3)( Ki = 0.013 µM). Also inhibits MMP-1, -2, -7-10, -12-14 and MMP-20. Attenuates inflammation-induced thermal hyperalgesia.NNGH is a potent inhibitor of matrix metalloproteinase-3...

    €717 - €2,091
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  • MMP-3 Substrate, NFF-3

    Biovision | MMP-3 Substrate, NFF-3 | B1060

    NFF-3 is a useful fluorogenic substrate for MMP-3 (stromelysin 1). NFF-3 is hydrolyzed rapidly by MMP-3 (kcat/Km = 218,000 s-1 M-1) and very slowly by MMP-9 (kcat/Km = 10,100 s-1 M-1), but no significant hydrolysis by MMP-1 and MMP-2.NFF-3 is a useful...

    €717 - €2,190
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  • MMP-13 inhibitor

    Biovision | MMP-13 inhibitor | 2392

    CL-82198 is a selective inhibitor of MMP-13 (IC₅₀ = 10 µM). It displays no activity against MMP-1, MMP-9 or TACE.CL-82198 is a selective inhibitor of MMP-13 (IC₅₀ = 10 µM). It displays no activity against MMP-1, MMP-9 or TACE.Biovision | 2392 | MMP-13...

    €717 - €6,750
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  • MMAE

    Biovision | MMAE | B2344

    MMAE (Monomethyl auristatin E) is a synthetic derivative of dolastatin 10 that functions as a potent mitotic inhibitor by inhibiting tubulin polymerization. Suppresses tumor cell viability in vitro (GIC50 values are 0.22, 0.49 and 0.54 nM in BT474,...

    €717 - €2,091
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  • MLS-573151

    Biovision | MLS-573151 | 1929

    Cell-permeable. A potent and specific inhibitor of Cdc42, a small GTPase of the Rho subfamily (IC₅₀ = 2 µM).MLS-573151 is a potent and specific inhibitor of Cdc42, a small GTPase of the Rho subfamily (IC₅₀ = 2 µM).Biovision | 1929 | MLS-573151...

    €741 - €2,190
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  • MLR-1023

    Biovision | MLR-1023 | 2685

    MLR-1023 is an allosteric activator of Lyn kinase (EC₅₀ = 63 nM). It reduces blood glucose levels without increasing insulin secretion in vivo. MLR-1023 does not activate peroxisome proliferator-activated α, d, and g receptors or glucagon-like peptide-1...

    €717 - €2,091
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  • MLN-9708

    Biovision | MLN-9708 | B2195

    MLN-9708 is a prodrug of Ixazomib citrate (MLN-2238). MLN-9708 is an orally bioavailable next-generation proteasome inhibitor (PI) with potential potent anticancer activity in both hematologic and solid tumor xenograft models with better pharmacokinetic...

    €717 - €2,091
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  • MLN8237

    Biovision | MLN8237 | 2718

    MLN8237 is a potent and selective inhibitor of Aurora kinase A (IC₅₀ =1.2 nM). It displays >200-fold higher selectivity for Aurora kinase A over Aurora kinase B. Displays antineoplastic activity.MLN8237 is a potent and selective inhibitor of Aurora...

    €1,062 - €3,444
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  • MLN-8054

    Biovision | MLN-8054 | B1943

    MLN-8054 is a potent and selective inhibitor of Aurora kinase A (IC₅₀ = 4 nM). Displays 40-fold selectivity for Aurora A over Aurora B.MLN-8054 is a potent and selective inhibitor of Aurora kinase A (IC₅₀ = 4 nM). Displays 40-fold selectivity for Aurora...

    €909 - €2,877
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  • MLN-4924

    Biovision | MLN-4924 | 2566

    A potent and selective inhibitor of NEDD8 (Neural precursor cell expressed, developmentally down-regulated 8)-activating enzyme (NAE) (IC₅₀ = 4.7 nM) with potential anticancer activity. NAE activates NEDD8, an ubiquitin-like (UBL) protein that modifies...

    €762 - €1,062
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  • MLN2480

    Biovision | MLN2480 | B1706

    MLN 2480(BIIB-024) is an oral, selective pan-Raf kinase inhibitor in clinical trials.MLN 2480(BIIB-024) is an oral, selective pan-Raf kinase inhibitor in clinical trials.Biovision | B1706 | MLN2480 DataSheetAlternate Name/Synonyms: MLN2480; ML-N2480; ML...

    €813 - €2,484
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  • ML-7 hydrochloride

    Biovision | ML-7 hydrochloride | B2000

    ML-7 hydrochloride is a selective MLCK (myosin light chain kinase) inhibitor (Ki = 0.3 μM). Displays reversible, ATP-competitive inhibition of Ca²⁺-calmodulin-dependent and -independent smooth muscle MLCKs.ML-7 hydrochloride is a selective MLCK (myosin...

    €666 - €1,893
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  • ML-365

    Biovision | ML-365 | B2076

    ML-365 is a potent and selective TASK-1 (K2P3.1/KCNK3) channel blocker (IC₅₀ values are 4 and 390 nM at TASK-1 and TASK-3, respectively). Displays little or no inhibition at Kir2.1, voltage-gated potassium channels, KCNQ2 and KV11.1 (hERG).ML-365 is a...

    €1,011 - €3,321
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  • ML-354

    Biovision | ML-354 | 9415

    ML-354 is a selective PAR4 antagonist (IC₅₀ = 140 nM). Displays 71-fold selectivity for PAR4 over PAR1 (PAR-1 IC₅₀ = 10 μM).ML-354 is a selective PAR4 antagonist (IC₅₀ = 140 nM). Displays 71-fold selectivity for PAR4 over PAR1 (PAR-1 IC₅₀ = 10 μM)...

    €666 - €7,140
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  • ML-35

    Biovision | ML-35 | B2077

    ML-335 is a potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator with EC₅₀ of 14.3 and 5.2 uM, respectively.ML-335 is a potent, selective K2P2.1 (TREK-1) and K2P10.1 (TREK-2) channels activator with EC₅₀ of 14.3 and 5.2 uM,...

    €1,011 - €3,321
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  • ML-324

    Biovision | ML-324 | 2763

    Cell-permeable. ML-324 is a JMJD2 histone demethylase inhibitor (JMJD2 IC₅₀ = 920 nM). Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC₅₀ ~ 10 µM) and abrogates infection. Represses the reactivation of HSV from the latent...

    €615 - €1,650
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  • ML243

    Biovision | ML243 | 2515

    ML-243 is a selective inhibitor of cancer stem cells. Displays 32-fold selective inhibition of a breast cancer stem cell-like cell line (EC₅₀ = 2.0 µM) over a control (mammary epithelial) cell line (EC₅₀ = 64 µM). It weakly antagonizes the adenosine A2A...

    €717 - €1,995
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  • Ml241

    Biovision | Ml241 | 2697

    ML241 is a potent, selective, and reversible inhibitor of the AAA ATPase p97 (IC₅₀ = 100 nM). It blocks p97-dependent proteasome substrate with an IC₅₀ of ~ 3500 nM.ML241 is a potent, selective, and reversible inhibitor of the AAA ATPase p97 (IC₅₀ = 100...

    €717 - €2,091
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  • ML-240

    Biovision | ML-240 | B1142

    ML-240 is an ATP-competitive inhibitor of the D2 domain of the p97 ATPase (IC₅₀ = 110 nM). It disrupts the endoplasmic reticulum-associated degradation and autophagy pathways, preventing the degradation of p97-dependent proteasome substrates (IC₅₀ = 0.9...

    €864 - €2,682
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  • ML230

    Biovision | ML230 | B2389

    A selective ATP-Binding Cassette Subfamily G Member 2 Efflux Inhibitor. displays selectivity toward ABCG2 over ABCB1ML230 is a selective ATP-Binding Cassette Subfamily G Member 2 Efflux Inhibitor. displays selectivity toward ABCG2 over ABCB1Biovision |...

    €666 - €1,893
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  • ML-204

    Biovision | ML-204 | 9448

    ML-204 is a selective blocker of TRPC4 channels. Displays 19-fold selectivity against TRPC6 and 9-fold selectivity against TRPC5; shows no significant activity at TRPV1, TRPV3, TRPA1 and TRPM8 channels even at concentrations up to 22 μM.ML-204 is a...

    €909 - €2,901
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  • ML-162

    Biovision | ML-162 | B2304

    ML-162 is a GPX4 (glutathione peroxidase 4) inhibitor that is selectively lethal to mutant RAS oncogene-expressing cell lines (IC₅₀s = 25 and 578 nM for HRASG12V-expressing and wild-type BJ fibroblasts, respectively).ML-162 is a GPX4 (glutathione...

    €666 - €1,893
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  • ML161

    Biovision | ML161 | 2689

    ML161 is an allosteric Inhibitor of protease-activated receptor 1 (PAR1)-mediated platelet activation (IC₅₀ = 0.26 μM for the inhibition of platelet P-selectin expression on human platelets). Also inhibits thrombin-induced platelet activation.ML161 is an...

    €717 - €2,091
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  • ML130

    Biovision | ML130 | 1974

    Cell-permeable. A selective NOD1 (nucleotide-binding oligomerization domain 1) inhibitor. Selectively inhibits NOD1-dependent activation of NF-kB in HEK293 cells (IC₅₀ = 0.56±0.04 µM). Displays high selectivity (>36-fold) over MDP-stimulated signaling in...

    €693 - €1,995
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  • MK-8931

    Biovision | MK-8931 | B1315

    MK-8931 is a potent BACE1 inhibitor. MK-8931 binds significantly to β-secretase.MK-8931 is a potent BACE1 inhibitor. MK-8931 binds significantly to β-secretase.Biovision | B1315 | MK-8931 DataSheetAlternate Name/Synonyms:...

    €813 - €2,337
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  • MK-7655

    Biovision | MK-7655 | B2289

    MK-7655 is a potent and selective β-lactamase inhibitor. It restores imipenem-susceptibility in imipenem-resistant K. pneumoniae and P. aeruginosa when used at concentrations of 12.5 and 4.7 μM, respectively.MK-7655 is a potent and selective β-lactamase...

    €909 - €2,877
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  • MK-571 sodium

    Biovision | MK-571 sodium | 2692

    MK-571 sodium is the sodium salt of the multidrug resistance protein-1 (MRP1) inhibitor MK-571 (Cat. No. 2691).MK-571 sodium is a selective, CysLT1 receptor antagonist. It blocks the binding of leukotriene LTD4, but not LTC4, to human and guinea pig lung...

    €864 - €2,631
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  • MK-571

    Biovision | MK-571 | 2691

    MK 571 is a selective, CysLT1 receptor antagonist. It blocks the binding of leukotriene LTD4, but not LTC4, to human and guinea pig lung membranes with Ki values of 0.22 nM and 2.1 nM, respectively. MK 571 effectively blocks LTD4 activation of...

    €813 - €2,484
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  • MK-5172

    Biovision | MK-5172 | B2118

    MK-5172 is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant variants.MK-5172 is a selective inhibitor of Hepatitis C virus NS3/4a protease with broad activity across genotypes and resistant...

    €864 - €2,682
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  • MK-4827 (Tosylate)

    Biovision | MK-4827 (Tosylate) | B2003

    MK-4827 is a potent and selective PARP-1 and PARP-2 inhibitor with IC₅₀ values of 3.8 nM and 2.1 nM, respectively. It induces synthetic lethality in preclinical tumor models with loss of BRCA and PTEN function.MK-4827 is a potent and selective PARP-1 and...

    €1,107 - €3,666
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  • MK-4827

    Biovision | MK-4827 | 9462

    MK-4827 is a potent and selective PARP-1 and PARP-2 inhibitor with IC₅₀ values of 3.8 nM and 2.1 nM, respectively. It induces synthetic lethality in preclinical tumour models with loss of BRCA and PTEN function.MK-4827 is a potent and selective PARP-1...

    €1,401 - €4,647
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  • MK-3102

    Biovision | MK-3102 | 9599

    MK-3102 is a potent, selective and long-acting dipeptidyl peptidase-4 (DPP-4) inhibitor with IC₅₀ of 1.6 nM; highly selective over other proteases (QPP, DPP8, and FAP) tested.MK-3102 is a potent, selective and long-acting dipeptidyl peptidase-4 (DPP-4)...

    €717 - €2,091
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  • MK-2206

    Biovision | MK-2206 | 1888

    A highly selective non-ATP competitive allosteric Akt inhibitor with IC₅₀’s of 8 nM, 2 nM and 65 nM for Akt1, Akt2 and Akt3, respectively. MK-2206 potently inhibits phosphorylation of Thr³⁰⁸ and Ser⁴⁷³ in 3T3-L1 adipocytes with IC₅₀ values of 0.11 and 0...

    €729 - €1,107
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  • MK-1775

    Biovision | MK-1775 | 2373

    MK-1775 is a potent and selective inhibitor of the tyrosine kinase WEE1 (IC₅₀ = 5.2 nM). It selectively targets and inhibits WEE1, a tyrosine kinase that phosphorylates cyclin-dependent kinase 1 (CDC2) to inactivate the CDC2/cyclin B complex. Inhibition...

    €717 - €1,968
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  • MK-1439

    Biovision | MK-1439 | B1250

    MK-1439 (also known as Doravirine), is a non-reversible reverse transcriptase inhibitor used in the treatment of HIV/AIDS with IC50 values of 12, 9.7, and 9.7 nM against the wild type (WT), K103N and Y181C reverse transcriptase (RT) mutants, respectively...

    €1,011 - €3,174
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  • MK-0941

    Biovision | MK-0941 | B1207

    MK-0941 is selective, allosteric glucokinase activator (GKA) that activates glucokinase (hexokinase subtype IV) with greater selectivity than over different hexokinase isoforms. MK-0941 shows decrease in mean fasting plasma glucose in healthy...

    €864 - €2,682
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