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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • LY2228820

    Biovision | LY2228820 | B1702

    LY2228820 is a novel and potent inhibitor of p38 MAPK with IC50 of 7 nM in a cell-free assay, but does not alter p38 MAPK activation.LY2228820 is a novel and potent inhibitor of p38 MAPK with IC50 of 7 nM in a cell-free assay, but does not alter p38 MAPK...

    €864 - €2,682
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  • LY-2157299

    Biovision | LY-2157299 | 9475

    LY-2157299 is a potent and selective TGFβ receptor I (TβRI) inhibitor (IC₅₀ = 56 nM). LY-2157299 abolishes the TGFβ induced Smad2 phosphorylation in HUVEC cells. It also shows dose dependent potentiation of VEGF or bFGF induced cell proliferation in...

    €762 - €2,142
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  • LY-2109761

    Biovision | LY-2109761 | 9605

    LY-2109761 is a highly potent and selective TGFβ receptor type I and type II (TβRI/II) inhibitor with Ki of 38 nM and 300 nM respectively. It has been used to study the role of TGF-β signaling in tumor cell migration and metastasis in pancreatic tumor...

    €1,062 - €3,444
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  • LY-2090314

    Biovision | LY-2090314 | B1043

    LY-2090314 is a potent and selective ATP-competitive inhibitor of Glycogen synthase kinase-3 (GSK-3) (IC₅₀ = 1.5 NM for GSK-3α and 0.9 nM for GSK-3β). LY-2090314 plays an important role in many pathways, including initiation of protein synthesis, cell...

    €813 - €2,484
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  • LY 294002

    Biovision | LY 294002 | 1667

    A specific and cell-permeable inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) (IC₅₀ = 1.40 µM).LY 294002 is a specific and cell-permeable inhibitor of phosphatidylinositol 3-kinase (PI 3-kinase) (IC₅₀ = 1.40 µM).Biovision | 1667 | LY 294002...

    €666 - €1,770
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  • LXS-196

    Biovision | LXS-196 | B2092

    LXS-196 is an orally available protein kinase C (PKC) inhibitor with potential immunosuppressive and antineoplastic activities. Upon oral administration, LXS-196 binds to and inhibits PKC, which prevents the activation of PKC-mediated signaling pathways...

    €1,011 - €3,174
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  • LX-4211

    Biovision | LX-4211 | 9623

    LX-4211 is a potent dual sodium-glucose cotransporter (SGLT)1 and SGLT2 inhibitor and an anti-diabetic agent. Sotagliflozin significantly improves glycemic control, without increasing the rate of hypoglycemia measurements, in diabetic mice maintained on...

    €1,062 - €3,444
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  • LX-2343

    Biovision | LX-2343 | B2120

    LX-2343 is a neuroprotective agent for the treatment of Alzheimer's disease. LX2343 ameliorates cognitive dysfunction in APP/PS1 transgenic mice via both Aβ production inhibition and clearance promotion. LX2-343 dose-dependently decreases Aβ accumulation...

    €960 - €3,072
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  • Lumiracoxib

    Biovision | Lumiracoxib | B1987

    Lumiracoxib is a non-steroidal anti-inflammatory drug (NSAID) that acts as a potent and selective cyclooxygenase-2 (COX-2) inhibitor. Displays anti-inflammatory properties.Lumiracoxib is a non-steroidal anti-inflammatory drug (NSAID) that acts as a...

    €717 - €2,091
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  • LuAF21934

    Biovision | LuAF21934 | B1302

    Lu AF21934 is a brain-penetrating positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu4), that reduces the harmaline-induced hyperactivity.Lu AF21934 is a brain-penetrating positive allosteric modulator of the metabotropic...

    €813 - €2,337
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  • LSN-2814617

    Biovision | LSN-2814617 | B2345

    LSN-2814617 is a potent and selective positive allosteric modulator at the mGlu5 receptor (EC50 = 24 nM). It acts as a potent and selective potentiator of human and rat mGlu₅ receptors in vitro, displaying curve shift ratios of two to three fold in the...

    €666 - €1,893
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  • Loxoribine

    Biovision | Loxoribine | 2003

    A guanosine derivative that acts as a selective ligand for Toll-like receptor 7 (TLR7) via IFN. Activates natural killer cells and primes cytolytic precursor cells for activation by IL-2.Loxoribine is a guanosine derivative that acts as a selective...

    €642 - €1,554
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  • LOXO-101

    Biovision | LOXO-101 | B2291

    LOXO-101 is a potent, ATP-competitive TRK inhibitor with IC₅₀s in low nanomolar range for inhibition of all TRK family members in binding and cellular assays, with 100-fold selectivity over other kinases, with 2 to 20 nM cellular potency against the...

    €909 - €2,877
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  • Losartan potassium

    Biovision | Losartan potassium | 2750

    Losartan is a selective, non-peptide angiotensin II type 1 (AT1) receptor antagonist. Clinically useful antihypertensive agent. Inhibits collagen I synthesis.Losartan is a selective, non-peptide angiotensin II type 1 (AT1) receptor antagonist. Clinically...

    €615 - €1,701
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  • Loperamide hydrochloride

    Biovision | Loperamide hydrochloride | 2683

    Loperamide is an antidiarrheal agent that acts as a non-selective Ca²⁺ channel blocker. At nanomolar concentrations (Ki = 2 nM), Loperamide binds to µ-opioid receptors. Also acts as an mTOR-independent autophagy enhancer.Loperamide is an antidiarrheal...

    €615 - €864
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  • L-NAME hydrochloride

    Biovision | L-NAME hydrochloride | 2356

    A pro-drug of L- NG-Nitro-L-arginine (L-NOARG). Hydrolysis of the methyl ester of L-NAME by cellular esterases converts it into a fully functional L-NOARG that exhibits some selectivity for inhibition of neuronal and endothelial NOS isoforms (Ki values...

    €570 - €1,356
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  • LLL12

    Biovision | LLL12 | 1792

    A Stat3 phosphorylation inhibitor. LLL12 inhibits STAT3 phosphorylation (Tyr705) and STAT3 activities and down-regulates STAT3 downstream targets; inhibits proliferation, colony formation, and cell migration and induces apoptosis in various human breast...

    €936 - €2,484
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  • LJI-308

    Biovision | LJI-308 | B1233

    LJI308 is a potent pan-RSK inhibitor, with IC₅₀ values of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.LJI308 is a potent pan-RSK inhibitor, with IC₅₀ values of 6 nM, 4 nM, and 13 nM for RSK1, RSK2, and RSK3, respectively.Biovision |...

    €717 - €2,091
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  • Lisinopril dihydrate

    Biovision | Lisinopril dihydrate | B2132

    Lisinopril is a potent angiotensin converting-Enzyme (ACE) inhibitor (IC₅₀ = 4.7 nM). The administration of lisinopril can lower the diastolic and systolic blood pressure and higher the heart rate. Lisinopril is found to reduce the activity of plasma...

    €615 - €1,401
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  • Linsitinib, Free base

    Biovision | Linsitinib, Free base | 2294

    A potent, small-molecule dual insulin-like growth factor-1 receptor (IGF-1R)/insulin receptor (IR) kinase inhibitor. Inhibits IGF-1R and IR kinases with IC₅₀ values of 35 nM and 75 nM, respectively. Linsitinib selectively blocks the autophosphorylation...

    €864 - €2,583
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  • Lincomycin Hydrochloride

    Biovision | Lincomycin Hydrochloride | B1524

    Lincomycin is an antibiotic produced by Streptomyces lincolnensis. It inhibits bacterial protein synthesis by forming cross-links within the peptidyl transferase loop region of the 23S rRNA. It is effective against gram-positive bacteria.Lincomycin is an...

    €666 - €1,848
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  • Linamarin

    Biovision | Linamarin | 2749

    Linamarin is a cyanogenic glycoside defense compound produced by plants and insects. Found in cassava. Displays neurotoxic effects in rats. Linamarin induces memory and cognition deficits in rodents.Linamarin is a cyanogenic glycoside defense compound...

    €1,599 - €2,682
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  • LIMKi 3

    Biovision | LIMKi 3 | B1095

    LIMKi 3 is a potent, and cell-permeable inhibitor of LIMK1 (IC₅₀ = 7 nM) and LIMK2 (IC₅₀ = 8 nM) and inhibits coflin phosphorylation in MDA-MB-231 breast cancer cells without affecting tubulin polymerization or inducing cytotoxicity. It also reduces...

    €864 - €2,682
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  • LH-846

    Biovision | LH-846 | 9423

    LH-846 is a potent and selective inhibitor of casein kinase (CK) 1δ (IC₅₀ values are 290 nM, 1.3 μM and 2.5 μM for CK1δ, ε andα); displays no inhibitory activity at CK2. Inhibits CK1δ-dependent phosphorylation and degradation of PER1 protein. LH846...

    €960 - €3,072
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  • Leucettine L41

    Biovision | Leucettine L41 | 2617

    A potent inhibitor of DYRKs and CLKs. Interacts also with GSK-3α/β, CK2 and PIM1. Interacts with the complex IKfyve/Vac14/Fig4. Modulates alternative splicing of pre-mRNA in various cellular systems. Neuroprotective against APP-induced cell death. Useful...

    €762 - €2,043
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  • Lestaurtinib

    Biovision | Lestaurtinib | 1805

    An indolocarbazole derivative with antineoplastic properties. Acts as a potent inhibitor of several tyrosine kinases including FLT3, JAK2, and TrkA with IC₅₀ values of 3, 1, and

    €693 - €1,011
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  • Leelamine hydrochloride

    Biovision | Leelamine hydrochloride | 2717

    Leelamine is a diterpene molecule that displays weak affinity for the human central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors, exhibiting 20% displacement of [3H]-CP55940 at a concentration of 10 µM. Leelamine is also an inhibitor of...

    €717 - €2,091
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  • L-DON

    Biovision | L-DON | B1955

    L-DON is a glutamine antagonist produced naturally by Streptomyces; it inhibits several glutamine-dependent enzyme pathways as well as acts as an inhibitor of the mitochondrial enzyme, glutaminase (GLS), the primary producer of neuronal glutamate.L-DON...

    €666 - €1,893
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  • LDK-378

    Biovision | LDK-378 | B1928

    LDK-378 is a highly potent inhibitor of anaplastic lymphoma kinase (ALK) (IC₅₀ = 200 pM). It displays weaker inhibition against IGF-1R, InsR, and STK22D (IC50s = 8, 7, and 23 nM, respectively), and is minimally effective against a panel of other kinases...

    €666 - €1,893
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  • LDE-225 diphosphate

    Biovision | LDE-225 diphosphate | 2893

    LDE-225 diphosphate is the phosphate analog of Smoothened (Smo) antagonist LDE-225 (Cat. No. 2892).LDE-225 diphosphate is the phosphate analog of Smoothened (Smo) antagonist LDE-225 (Cat. No. 2892).Biovision | 2893 | LDE-225 diphosphate...

    €909 - €2,829
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  • LDE-225

    Biovision | LDE-225 | 2892

    LDE225 is a potent and selective antagonist of Smoothened (Smo) with IC₅₀ values of 2.5 nM and 1.3 nM for human and mouse Hedgehog, respectively. LDE-225 induces dose-related inhibition of Hh and Smo-dependent tumour growth.LDE225 is a potent and...

    €864 - €2,682
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  • L-Buthionine-(S,R)-Sulfoximine

    Biovision | L-Buthionine-(S,R)-Sulfoximine | B2305

    L-Buthionine-(S,R)-Sulfoximine is a potent, fast acting, irreversible inhibitor of gamma-glutamylcysteine synthetase the rate-limiting enzyme for L-glutathione (GSH) synthesis, that induces oxidative stress in cells by depleting GSH. Shown to improve the...

    €570 - €1,209
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  • LB-100

    Biovision | LB-100 | B2031

    LB-100 is a potent protein phosphatase 2A (PP2A) inhibitor with IC₅₀s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells. LB-100 is a potent protein phosphatase 2A (PP2A) inhibitor with IC₅₀s of 0.85 μM and 3.87 μM in BxPc-3 and Panc-1 cells. Biovision...

    €864 - €2,805
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  • Lasofoxifene tartrate

    Biovision | Lasofoxifene tartrate | 9680

    Lasofoxifene is a unique, non-steroidal selective estrogen receptor modulator (SERM). It selectively binds to human ERα with an IC₅₀ value of 1.5 nM and inhibits bone loss in ovariectomized rats. Has potential use in treating breast cancer.Lasofoxifene...

    €615 - €1,701
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  • LAQ824

    Biovision | LAQ824 | 2634

    LAQ824 (Dacinostat) is a potent HDAC inhibitor (IC₅₀ = 32 nM) that displays significant activity against multiple myeloma.LAQ824 (Dacinostat) is a potent HDAC inhibitor (IC₅₀ = 32 nM) that displays significant activity against multiple myeloma.Biovision...

    €666 - €1,893
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  • Lapatinib, Free base

    Biovision | Lapatinib, Free base | 2138

    A free base form of Lapatinib Ditosylate (Cat. No. 1624-25, 100).Lapatinib, Free base is a free base form of Lapatinib Ditosylate (Cat. No. 1624-25, 100).Biovision | 2138 | Lapatinib, Free base DataSheetAlternate Name/Synonyms: GSK 572016; GW-572016;...

    €888 - €1,770
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  • L-838,417

    Biovision | L-838,417 | B1281

    L-838, 417 is a subtype-selective GABAA receptor partial agonist. It selectively binds to α1, α2, α3 and α5 subunits (Kivalues are 0.79, 0.67, 0.67 and 2.25 nM respectively) but displays no efficacy at α1 (α1-sparing). Exhibits non-sedative anxiolytic,...

    €864 - €2,682
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  • L-778123 hydrochloride

    Biovision | L-778123 hydrochloride | 9638

    L-778123 hydrochloride is a potent inhibitor of FPTase and GGPTase-I with an IC₅₀ of 2 nM and 98 nM, respectively, in enzyme inhibition determination.L-778123 hydrochloride is a potent inhibitor of FPTase and GGPTase-I with an IC₅₀ of 2 nM and 98 nM,...

    €960 - €3,072
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  • L-755,507

    Biovision | L-755,507 | B1116

    L-755,507 is a partial agonist of β3-adrenergic receptors (EC₅₀ = 0.43 nM). It displays >440-fold selectivity for β3- over β1- and β2-adrenoceptors (EC₅₀s = 580 and >10,000 nM, respectively). Enhances CRISPR-mediated homology-directed repair (HDR)...

    €960 - €3,072
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  • L-67

    Biovision | L-67 | 9633

    L-67 is a competitive human DNA ligase inhibitor, that inhibits DNA ligases I and III with IC₅₀ values of 10 μM and 10 μM. L-67 significantly increases the cytotoxicity of DNA damaging agents. L-67 also inhibits cell proliferation.L-67 is a competitive...

    €864 - €2,682
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  • L-189

    Biovision | L-189 | 9674

    L-189 is a DNA ligase I, III and IV inhibitor (IC₅₀ values are 5, 9 and 5 μM respectively) that blocks DNA binding (Ki= 5 μM for DNA ligase I). L-189 inhibits base excision repair (BER) and non-homologous end joining (NHEJ). L-189 specifically sensitizes...

    €717 - €2,091
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  • KX-392 dihydrochloride

    Biovision | KX-392 dihydrochloride | B2189

    KX-392 is a potent oral non-ATP competitive inhibitor of Src kinase and tubulin polymerization. KX2-391 shows steep dose-response curves against Huh7 (GI₅₀ = 9 nM), PLC/PRF/5 (GI₅₀ = 13 nM), Hep3B (GI₅₀ = 26 nM), and HepG2 (GI₅₀ = 60 nM), four hepatic...

    €1,011 - €3,174
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  • KW-2449 hydrochloride

    Biovision | KW-2449 hydrochloride | B1208

    KW 2449 is a multikinase inhibitor of FLT3, ABL, ABL-T315I, and Aurora kinase. It displays potent inhibition of growth effects on leukemia cells with FLT3 mutations via inhibition of the FLT3 kinase. This leads in the down-regulation of...

    €813 - €2,484
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  • KT5823

    Biovision | KT5823 | 2164

    Cell-permeable. KT5823 is a derivative of K-252a (Cat. No. 2013) that acts as a selective inhibitor of Protein kinase G (PKG) (Ki = 0.234 µM). Inhibits other kinases at much higher concentrations (Ki’s for PKA = 4 μM and for MLCK=>10 μM).KT5823 is a...

    €741 - €2,142
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  • KT5720

    Biovision | KT5720 | 2276

    A derivative of the protein kinase inhibitor K252a (Cat. No. 2013). Acts as a potent, selective, ATP-competitive inhibitor of protein kinase A (PKA) (Ki = 60 nM). Has no effect on PKC, PKG and MLCK.KT5720 acts as a potent, selective, ATP-competitive...

    €864 - €1,401
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  • KS-176

    Biovision | KS-176 | B1272

    KS-176 is a potent and specific inhibitor of Breast Cancer Resistance Protein (BCRP) / ATP-binding cassette sub-family G member 2 (ABCG2). Displays no inhibitory activity against P-gp or MRP1.KS-176 is a potent and specific inhibitor of Breast Cancer...

    €864 - €2,682
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  • KN-93, Water-Soluble

    Biovision | KN-93, Water-Soluble | 1909

    Cell-permeable. A Potent and selective inhibitor of Ca²⁺/calmodulin-dependent protein kinase II (CaM kinase II) (IC₅₀ = 0.37 μM).KN-93, Water-Soluble is a potent and selective inhibitor of Ca²⁺/calmodulin-dependent protein kinase II (CaM kinase II) (IC₅₀...

    €888 - €2,436
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