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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • IKK16

    Biovision | IKK16 | B1087

    IKK-16 is a potent and selective inhibitor of IκB kinase (IKK) with IC₅₀ values from 40, 70 and 200 nM for IKKβ, IKK complex and IKKα respectively. It is effective in cells and in animals and has been used delineate the role of NF-κB signaling in diverse...

    £606 - £1,918
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  • IDO1 Inhibitor I

    Biovision | IDO1 Inhibitor I | 2745

    IDO1 Inhibitor I is a potent IDO1 inhibitor that displays IC₅₀ values of 67 and 19 nM for human IDO in enzymatic activity and HeLa cell assays, respectively. It is inactive against tryptophan 2,3-dioxygenase (IC₅₀ > 10 µM).IDO1 Inhibitor I is a potent...

    £478 - £1,394
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  • IDO Pathway inhibitor

    Biovision | IDO Pathway inhibitor | 2746

    IDO pathway inhibitor is a methylated tryptophan with anti-immunosuppressive activity. 1-Methyl-D-tryptophan inhibits the enzyme indoleamine 2,3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain...

    £380 - £1,002
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  • IDE-1

    Biovision | IDE-1 | 2193

    Cell-permeable. Directs differentiation of embryonic stem cells (ESCs) into the endodermal lineage (EC₅₀ = 125 nM). Nodal/Smad signaling is activated indicating IDE-1 functions via TGF-β-signaling pathway.IDE-1 directs differentiation of embryonic stem...

    £462 - £1,278
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  • Ibutamoren mesylate

    Biovision | Ibutamoren mesylate | B2400

    Ibutamoren is a non-peptidic, potent, long-acting, orally-active, and selective agonist of the ghrelin receptor and a growth hormone secretagogue. It mimicks the growth hormone (GH)-stimulating action of the endogenous hormone ghrelin. It stimulates GH...

    £410 - £1,066
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  • I-BET762

    Biovision | I-BET762 | 2628

    I-BET762 (GSK525762) is a highly potent, selective and cell-permeable inhibitor of the bromodomain and extra terminal (BET) family protein BRD4 (IC₅₀ of ~35 nM). It inhibits myeloma cell proliferation and suppresses the production of proinflammatory...

    £444 - £1,262
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  • I-BET726

    Biovision | I-BET726 | B1569

    I-BET276 is a potent, and selective small molecule inhibitor of BET proteins with high affinity to BRD2 (IC₅₀ = 41 nM), BRD3 (IC₅₀ = 31 nM), and BRD4 (IC₅₀ = 22 nM).I-BET276 is a potent, and selective small molecule inhibitor of BET proteins with high...

    £738 - £2,444
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  • IACS-010759

    Biovision | IACS-010759 | B2231

    IACS-010759 is a potent and selective Oxidative Phosphorylation Inhibitor (IC₅₀ < 10 nM) with potential antineoplastic activity. IACS-010759 robustly inhibits proliferation and induces apoptosis in models of brain cancer and acute myeloid leukemia (AML)...

    £542 - £1,656
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  • Hypoxanthine Disodium Salt

    Biovision | Hypoxanthine Disodium Salt | B1185

    Hypoxanthine is the purine base of the nucleoside inosine. Hypoxanthine may be used as a substrate to study the specificity and kinetics of hypoxanthine-guanine phosphoribosyl transferases. Also serves as a nutrient additive for a variety of cell culture...

    £346 - £738
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  • Hyperforin. DCHA

    Biovision | Hyperforin. DCHA | 2153

    Displays a variety of biological activities including anti-bacterial, anti-inflammatory, anticancer and anti-angiogenic effects. Also acts as an antidepressant and anxiolytic agent. Regulates expression of the cytochrome P450 CYP3A4 and CYP2C9 and...

    £738 - £1,100
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  • Hydroxyfasudil Hydrochloride

    Biovision | Hydroxyfasudil Hydrochloride | B1559

    Hydroxyfasudil is a metabolite of Fasudil (Cat. No. 1787), that acts as a potent Rho-kinase (ROCK) inhibitor [(IC₅₀ = 12 μM (ROCK1); 0.17 μM (ROCK2)]. Acts as a vasodilator.Hydroxyfasudil is a metabolite of Fasudil (Cat. No. 1787), that acts as a potent...

    £606 - £1,918
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  • HPI-1

    Biovision | HPI-1 | 2410

    HPI-1 is a Hedgehog pathway inhibitor acting downstream of Smo and independently of PKA, PI3K and MAPK. It can suppress Hh pathway activation induced by loss of Su(fu) or Gli overexpression. Inhibits both endogenous and exogenous Gli1/Gli2 activity...

    £542 - £1,656
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  • HM-30181

    Biovision | HM-30181 | B1285

    HM-30181 is a third-generation P-glycoprotein (P-gp) inhibitor. In an in vitro, HM-30181 displays a high selectivity for P-gp and its potency is 20–50 times higher than that of tariquidar (Cat. No. 2853), another third-generation P-gp inhibitor.HM-30181...

    £576 - £1,788
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  • HLCL-61 hydrochloride

    Biovision | HLCL-61 hydrochloride | B1209

    HLCL-61 is a potent and selective PRMT5 (potent arginine methyltransferase 5) inhibitor. It shows no inhibitory activity against the type I (PRMT1 and PRMT4) and type II (PRMT7) PRMT family members. In vitro data shows HLCL-61 effectively inhibits...

    £542 - £1,656
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  • Hh-Ag1.5

    Biovision | Hh-Ag1.5 | B2160

    Hh-Ag 1.5 is a potent and selective agonist of the Hh pathway (Smoothened/Smo agonist) (EC₅₀ = 1 nM).Hh-Ag 1.5 is a potent and selective agonist of the Hh pathway (Smoothened/Smo agonist) (EC₅₀ = 1 nM).Biovision | B2160 | Hh-Ag1.5 DataSheetAlternate...

    £708 - £2,296
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  • HG-10-012-01

    Biovision | HG-10-012-01 | 2604

    Brain-permeable. HG-10-102-01 is a potent and selective inhibitor of wild-type LRRK2 and the G2019S mutant (IC₅₀ values are ~20.3 nM and ~ 3.2 nM, respectively). It significantly inhibits Ser910 and Ser935 phosphorylation of both wild-type LRRK2 and...

    £576 - £1,754
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  • Herbimycin A

    Biovision | Herbimycin A | 2748

    Herbimycin A is an ansamycin antibiotic isolated from Streptomyces sp. Inhibits HSP90 and associated client proteins including v-Src, Bcr-Abl, Raf-1 and ErbB2. Herbimycin A reverts tyrosine kinase-induced oncogenic transformation without direct...

    £904 - £3,278
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  • Heptelidic Acid

    Biovision | Heptelidic Acid | 2215

    A sesquiterpene antibiotic, isolated from Trichoderma sp. A potent and selective glyceraldehyde 3-phosphate dehydrogenase (GAPDH) inhibitor. Binds to the essential Cys149 residue in the catalytic site of GAPDH. Selectively kills high-glycolytic cancer...

    £674 - £1,492
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  • Heparin-Binding Peptide III

    Biovision | Heparin-Binding Peptide III | 1823

    A heparin-binding peptide derived from bone sialoprotein. Surfaces displaying this peptide support human embryonic stem (hES) cell adhesion and self-renewal.Heparin-Binding Peptide III is a peptide derived from bone sialoprotein. Surfaces displaying this...

    £428 - £1,180
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  • Heparin-Binding Peptide II

    Biovision | Heparin-Binding Peptide II | 1822

    A heparin-binding peptide derived from fibronectin. Surfaces displaying this peptide support human embryonic stem (hES) cell adhesion and self-renewal.Heparin-Binding Peptide II is a peptide derived from fibronectin. Surfaces displaying this peptide...

    £444 - £1,248
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  • Heparin-Binding Peptide I

    Biovision | Heparin-Binding Peptide I | 1821

    A heparin-binding peptide derived from vitronectin. Surfaces displaying this peptide support human embryonic stem (hES) cell adhesion and self-renewal.Heparin-Binding Peptide I is a peptide derived from vitronectin. Surfaces displaying this peptide...

    £478 - £1,362
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  • HDM Inhibitor, 2,4-PDCA

    Biovision | HDM Inhibitor, 2,4-PDCA | 2304

    A histone-lysine demethylase (HKDM) inhibitor. Inhibits JARID1 proteins with an IC₅₀ values of 4.3 µM for JARID1B and 4.1 µM for JARID1A. 2, 4-PDCA does not inhibit UTX even at 10 µM.A histone-lysine demethylase (HKDM) inhibitor. Inhibits JARID1 proteins...

    £346 - £708
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  • HDAC Substrate, Fluorogenic

    Biovision | HDAC Substrate, Fluorogenic | 2396

    A useful fluorometric substrate for histone deacetylases (HDACs). Ex(max): 330nm; Em(max): 395nm.HDAC substrate, fluorogenic is a useful substrate for histone deacetylases (HDACs).Biovision | 2396 | HDAC Substrate, Fluorogenic DataSheetAlternate...

    £542 - £1,558
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  • HC Toxin

    Biovision | HC Toxin | 2728

    HC Toxin is a cyclic tetrapeptide first isolated from H. carbonum (now C. carbonum), a pathogen of maize. It is a reversible inhibitor of histone deacetylases (HDACs) (IC₅₀ = 30 nM). Through its effects on HDACs, HC toxin has been shown to up-regulate...

    £708 - £1,134
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  • HBX-41108

    Biovision | HBX-41108 | 9608

    HBX-41108 is a potent inhibitor of ubiquitin-specific protease (USP) 7 activity (IC₅₀ = 424 nM). Also inhibits USP7-mediated p53 deubiquitination (IC₅₀ = 0.8 μM). HBX-41108 treatment stabilizes p53, activates the transcription of a p53 target gene...

    £806 - £2,704
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  • HAT Activator, CTPB

    Biovision | HAT Activator, CTPB | 2086

    A potent activator of p300 HAT (histone acetyltransferase), but not of PCAF (p300/CBP-associated factor) HAT activities.HAT Activator, CTPB is a potent activator of p300 HAT (histone acetyltransferase), but not of PCAF (p300/CBP-associated factor) HAT...

    £494 - £1,018
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  • HA 130

    Biovision | HA 130 | B1192

    HA 130 is a potent and eversible inhibitor of autotaxin (ATX) (IC₅₀ = 28 nM). It does not affect the activity of any proteasomal protease or related enzymes. HA-130 rapidly decreases plasma lysophosphatidic acid levels in mice when given intravenously (1...

    £444 - £1,262
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  • H-89 Dihydrochloride

    Biovision | H-89 Dihydrochloride | 1768

    A cell-permeable, ATP-competitive inhibitor of Protein Kinase A (PKA) (IC₅₀ = 50 nM). Also inhibits other kinases, including MSK1 , S6K1 and ROCKII with IC₅₀ values of 120 nM, 80 nM and 270 nM respectively.H-89 is a cell-permeable, ATP-competitive...

    £478 - £1,376
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  • H-7 dihydrochloride

    Biovision | H-7 dihydrochloride | 9543

    H-7 is a Protein kinase inhibitor that inhibits the activity of PKA, PKC, PKG and MLCK with IC₅₀ values of 3.0, 6.0, 5.8 and 97.0 µM, respectively.H-7 is a Protein kinase inhibitor that inhibits the activity of PKA, PKC, PKG and MLCK with IC₅₀ values of...

    £542 - £1,656
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  • H3B-6527

    Biovision | H3B-6527 | B1647

    H3B-6527 is an orally bioavailable inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential antineoplastic activity.H3B-6527 is an orally bioavailable inhibitor of human fibroblast growth factor receptor 4 (FGFR4), with potential...

    £854 - £2,818
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  • GYY 4137

    Biovision | GYY 4137 | 1908

    A slow-releasing, water-soluble hydrogen sulfide (H₂S) donor. Displays vasodilator and antihypertensive activity in rats in both acute (L-NAME-induced) or chronic (spontaneously hypertensive) hypertension models. Inhibits LPS-induced release of various...

    £410 - £1,036
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  • GW-786034

    Biovision | GW-786034 | 1916

    Cell-permeable. A potent and selective multi-targeted tyrosine kinase inhibitor that targets vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor and c-kit, key proteins responsible for tumor growth and...

    £394 - £934
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  • GW-7647

    Biovision | GW-7647 | 9571

    GW-7647 is a potent, selective agonist of human and murine PPARα. It activates human PPARα, PPARγ, and PPARδ with EC₅₀ values of 0.006, 1.1 and 6.2 µM, respectively, in a GAL4-PPAR binding assay. Similar EC₅₀ values of 0.001, 1.3, and 2.9 were observed...

    £640 - £2,048
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  • GW-6471

    Biovision | GW-6471 | 9453

    GW-6471 is a potent PPARα antagonist (IC₅₀ = 240 nM). It drives the displacement of coactivators from PPARα and promotes the recruitment of co-repressor proteins like nuclear co-repressor. GW-6471 significantly prevents cardiomyocyte differentiation and...

    £410 - £1,134
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  • GW-5074

    Biovision | GW-5074 | 2412

    Cell-permeable. A potent inhibitor of cRAF1 kinase (IC₅₀ = 9 nM). Displays 100-fold selectivity for cRAF1 over CDK1, CDK2, c-src, ERK2, MEK, p38, Tie2, VEGFR2 and c-fm. Displays neuroprotective effects in vivo via a mechanism that is independent of MEK,...

    £542 - £1,656
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  • GW501516

    Biovision | GW501516 | 1971

    A selective agonist for PPARδ (peroxisome proliferator-activated receptorδ) (EC₅₀ = 1. 1 nM), displaying 1000-fold selectivity over the other human subtypes. In macrophages, fibroblasts, and intestinal cells, GW501516 increases expression of the reverse...

    £462 - £1,362
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  • GW-441756

    Biovision | GW-441756 | B1147

    GW-441756 is potent and specific inhibitor of Trk A (tropomyosin-related kinase A) tyrosine kinase (IC₅₀ = 2 nM). This inhibition of TrkA reduces cell proliferation and enhances the effects of chemotherapeutic agents in sarcoma. GW-441756 displays...

    £606 - £1,918
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  • GW-4064

    Biovision | GW-4064 | B2278

    GW-4064 is a potent and selective, non-steroidal farnesoid X receptor (FXR) agonist (EC₅₀ = 15 nM). Displays no activity at other nuclear receptors at concentrations up to 1 μM. Improves hyperglycemia and hyperlipidemia in diabetic db/db mice. Shown to...

    £508 - £1,526
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  • GW-3965 hydrochloride

    Biovision | GW-3965 hydrochloride | 9402

    GW-3965 hydrochloride is a non-steroidal liver X receptor agonist on hLXRα and hLXRβ. GW3965 has an EC₅₀ = 125 nM in a cell-free ligand-sensing assay of LXRα and profiles as a full agonist on hLXRα and hLXRβ in cell-based assays with EC₅₀ = 190 nM and 30...

    £640 - £2,048
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  • GW-0742

    Biovision | GW-0742 | B1100

    GW 0742 is a potent and selective PPARδ agonist (EC₅₀ = 1.1 nM) that displays 1,000-fold selectivity over other human PPAR subtypes. Therapeutically has shown to have effect on pulmonary damage, inflammatory and apoptotic parameters in mice. It increases...

    £576 - £1,788
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  • GW 9508

    Biovision | GW 9508 | 2817

    GW 9508 is a potent and selective agonist for the free fatty acid receptor FFA1 (GPR40) with pEC₅₀ of 7.32; 100-fold selective against GPR120. Inactive against a range of other GPCRs, kinases, proteases, integrins and PPARs. Potentiates...

    £606 - £1,918
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  • GW 4869 dihydrocloride

    Biovision | GW 4869 dihydrocloride | 2417

    GW 4869 is a cell-permeable, non-competitive inhibitor of neutral sphingomyelinases (IC₅₀ = 1 μM), but does not affect acid sphingomyelinase activity. It inhibits TNF-α-mediated sphingomyelin hydrolysis (100% inhibition at 20 μM) and TNF-α-induced cell...

    £410 - £1,066
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  • GSNO

    Biovision | GSNO | 1580

    Carrier of nitric oxide, relaxing smooth muscles and inhibiting platelet activation.GSNO is a carrier of nitric oxide, relaxing smooth muscles and inhibiting platelet activation.Biovision | 1580 | GSNO DataSheetAlternate Name/Synonyms:...

    £508 - £1,180
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  • GSK-J4 hydrochloride

    Biovision | GSK-J4 hydrochloride | 2259

    Cell-permeable. An ethyl ester derivative of the JMJD3 selective histone demethylase inhibitor GSK-J1 (Cat. No. 2260-1, 5) (IC₅₀> 50 μM in vitro. When administered to human primary macrophages, GSK-J4 can reduce lipopolysaccharide (LPS)-induced...

    £364 - £806
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  • GSK-J4 (Free base)

    Biovision | GSK-J4 (Free base) | 2762

    GSK- J4 is cell-permeable ethyl ester of GSK-J1 (Cat. Nos. 2260 & 2761). Acts as a histone demethylase JMJD3/UTX inhibitor. Inhibits demethylation of histone H3K27. Reduces LPS-induced proinflammatory cytokine production in primary human macrophages...

    £380 - £806
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  • GSK-J1 sodium salt

    Biovision | GSK-J1 sodium salt | 2260

    A potent and selective inhibitor of the H3K27 histone demethylases JMJD3 and UTX (IC₅₀ = 60 nM for human JMJD3 in vitro). It is inactive against a panel of other JMJ family demethylases, including several variants of JMJD2 and JMJD1 and, at higher...

    £364 - £806
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  • GSK-J1 (Free acid)

    Biovision | GSK-J1 (Free acid) | 2761

    GSK-J1 is a potent and selective inhibitor of jumonji H3K27 histone demethylases JMJD3 and UTX (IC₅₀ = 60 nM, human JMJD3). This is the first known inhibitor selective for the H3K27me3-specific JMJ subfamily which binds to the active catalytic site of...

    £380 - £806
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  • GSK-961081

    Biovision | GSK-961081 | B1590

    GSK-961081 is a bi-functional molecule with both muscarinic antagonism and β2-agonism (MABA) properties. GSK-961081 displays high affinity for hM2 (Ki = 1.4 nM), hM3 muscarinic receptors (Ki = 1.3 nM) and hβ2-adrenoceptors (Ki = 3.7 nM).GSK-961081 is a...

    £738 - £2,444
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