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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • DAPI

    Biovision | DAPI | B1098

    DAPI is a fluorescent, cell-permeable DNA-binding dye preferentially binds to DNA rich in adenine and thymine. DAPI is useful in measuring nuclear DNA content using flow cytometry for sorting isolated chromosomes and is also useful for microscopic...

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  • Dantrolene sodium

    Biovision | Dantrolene sodium | 2491

    Dantrolene sodium is an inhibitor of Ca²⁺ release from sarcoplasmic reticulum via inhibition of ryanodine receptor (RYR) channels. Displays selectivity for RYR1 and RYR3 over RYR2. Acts asa skeletal muscle relaxant that depresses excitation-contraction...

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  • Damnacanthal

    Biovision | Damnacanthal | B1094

    Damnacanthal is a potent and inhibitor of p56lck tyrosine kinase and inhibits autophosphorylation with IC50 of 17 nM and phosphorylation of exogenous substrates with IC50 of 620 nM in cell free assays. Damnacanthal Displays 7- to 20-fold selectivity over...

    £738 - £2,444
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  • Daclatasvir dihydrochloride

    Biovision | Daclatasvir dihydrochloride | B2224

    Daclatasvir is a highly selective inhibitor of HCV NS5A with EC₅₀ of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture.Daclatasvir is a highly selective inhibitor of HCV NS5A with EC₅₀ of 9-50...

    £444 - £1,262
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  • D-(+)-Biotin

    Biovision | D-(+)-Biotin | 9587

    D-(+)-Biotin is a coenzyme and a B vitamin. May be used to elute proteins from avidin/streptavidin resins.D-(+)-Biotin is a coenzyme and a B vitamin. May be used to elute proteins from avidin/streptavidin resins.Biovision | 9587 | D-(+)-Biotin...

    £738 - £1,066
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  • D (+)-Cycloserine

    Biovision | D (+)-Cycloserine | B1188

    D-Cycloserine is a partial agonist at the glycine modulatory site of NMDA glutamatergic receptors. Blocks kainate-induced seizures and displays anticonvulsant effects in rat models. D-Cycloserine facilitates synaptic plasticity but impairs glutamatergic...

    £410 - £984
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  • CZC-54252 hydrochloride

    Biovision | CZC-54252 hydrochloride | 9567

    CZC-54252 is a potent inhibitor of leucine-rich repeat kinase 2 (LRRK2) (IC₅₀ values are 1.28 nM and 1.85 nM for wild-type and G2019S mutant forms of LRRK2 respectively). CZC-54252 attenuates neuronal injury induced by LRRK2-G2019SCZC-54252 is a potent...

    £640 - £2,048
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  • Cytochlor

    Biovision | Cytochlor | 2833

    Cytochlor is a radio-sensitizing pyrimidine nucleoside with potential antineoplastic activity. Cytochlor could be a potentially useful reagent to study chlorine-stressed DNA.Cytochlor is a radio-sensitizing pyrimidine nucleoside with potential...

    £772 - £2,444
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  • Cytochalasin D

    Biovision | Cytochalasin D | B1176

    Cytochalasin D is a cell-permeable fungal toxin that acts as a potent inhibitor of actin polymerization; disrupts actin microfilaments; activates the p53-dependent pathways. It is about 10-fold more effective than Cytochalasin B and does not inhibit...

    £606 - £1,918
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  • Cyt387

    Biovision | Cyt387 | 2316

    Cyt387 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC₅₀ values of 11 nM and 18 nM, respectively. Inhibits JAK3 at much higher concentrations (IC₅₀ = 155 nM).Cyt387 is an ATP-competitive inhibitor of JAK1 and JAK2 with IC₅₀ values of 11 nM and...

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  • Cyclosporine A

    Biovision | Cyclosporine A | 1522

    A fungal metabolite possessing potent immunosuppressive properties. It inhibits the T-cell receptor signal transduction pathway via the formation of cyclosporin A−cyclophilin complex that inhibits calcineurin (protein phosphatase 2B.Cyclosporine A is a...

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  • Cyclophosphamide monohydrate

    Biovision | Cyclophosphamide monohydrate | 9657

    Cyclophosphamide is a cytotoxic agent commonly used in cancer chemotherapy. It cross-links DNA, causes strand breakage, and induces mutations. Its clinical activity is associated with a decrease in aldehyde dehydrogenase 1 (ALDH1) activity. Also displays...

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  • Cyclopamine tartrate

    Biovision | Cyclopamine tartrate | 2518

    Cyclopamine tartrate is a water-soluble derivative of the Hedgehog (Hh) signaling pathway inhibitor Cyclopamine (Cyc) (Cat. No.1578). Displays higher inhibitory activity for Hh signaling-dependent motor neuron differentiation than did Cyc (IC₀ = 50...

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  • Cyclo(RGDfK)

    Biovision | Cyclo(RGDfK) | B2363

    Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin (IC₅₀ = 0.94 nM)Cyclo(-RGDfK) is a potent and selective inhibitor of the αvβ3 integrin (IC₅₀ = 0.94 nM)Biovision | B2363 | Cyclo(RGDfK) DataSheetAlternate Name/Synonyms:...

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  • CX-4945

    Biovision | CX-4945 | 2459

    A selective, ATP-competitive, Casein kinase -2 (CK2) inhibitor (Ki = 0.38 nM). Displays potent anti-tumor activity in several cancer cell lines.CX-4945 is a selective, ATP-competitive, Casein kinase -2 (CK2) inhibitor (Ki = 0.38 nM).Biovision | 2459 |...

    £542 - £1,656
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  • CW069

    Biovision | CW069 | 9507

    CW069 is an allosteric inhibitor of the microtubule motor protein HSET that induces multipolar mitoses only in cells containing supernumerary centrosomes.CW069 is an allosteric inhibitor of the microtubule motor protein HSET that induces multipolar...

    £576 - £1,788
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  • Curvularin

    Biovision | Curvularin | 9694

    Isolated from Penicillium sp. Displays cytotoxic, antifungal, anti-inflammatory, and antiprotozoal properties. Acts as a TGF-β signaling pathway inhibitor as well as inducible nitric oxide synthase (iNOS; NOSII) inhibitor. Also, inhibits cell division...

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  • Curcubitacin E

    Biovision | Curcubitacin E | B1592

    Curcubitacin E is a potent actin depolymerization inhibitor. Shown to have a different mechanism of action compared to Jasplakinolide (Cat. No. 1689), binding to a different site. Binds specifically to filamentous actin (F-actin) forming a covalent bond...

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  • CUR-61414

    Biovision | CUR-61414 | 2743

    CUR-61414 is a potent, cell-permeable , Hedgehog signaling pathway inhibitor (IC₅₀ = 100-200 nM). Selectively binds to Smo but not other GPCRs. CUR 61414 blocks proliferation and induces apoptosis in mouse basal cell carcinoma and causes regression of...

    £576 - £1,788
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  • CUDC-907

    Biovision | CUDC-907 | B1675

    CUDC-907 potently inhibits class I PI3Ks as well as classes I and II HDAC enzymes.CUDC-907 potently inhibits class I PI3Ks as well as classes I and II HDAC enzymes.Biovision | B1675 | CUDC-907 DataSheetAlternate Name/Synonyms: CUDC-907; CUDC907; CUDC...

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  • CUDC-305

    Biovision | CUDC-305 | 9653

    CUDC-305 is a potent inhibitor of Heat Shock Proteins, displaying high affinity for HSP90α/β (IC₅₀ = 100 nM) and HSP90 complex derived from cancer cells (IC₅₀ = 48.8 nM).CUDC-305 is a potent inhibitor of Heat Shock Proteins, displaying high affinity for...

    £444 - £1,134
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  • CT-2584

    Biovision | CT-2584 | B1182

    CT-2584 is a cytotoxic agent that alters phospholipid biosynthesis via inhibition of CTP:choline-phosphate cytidylyltransferase causing an increase in phosphatidylinositol will decreasing levels of phosphatidylcholine. The altered phospholipid metabolism...

    £806 - £2,542
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  • CRT0066101

    Biovision | CRT0066101 | B1847

    CRT0066101 is a potent inhibitor of protein kinase D (PKD). It inhibits all PKD isoforms (IC₅₀ values are 1, 2 and 2.5 nM for PKD1, PKD3 and PKD2 respectively). It displays selectivity for PKD against a panel of >90 protein kinases, including PKCα, MEK,...

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  • CRT Inhibitor, iCRT5

    Biovision | CRT Inhibitor, iCRT5 | 1896

    Cell-permeable. A potent inhibitor of the β-catenin-responsive transcription (CRT) in the nucleus. iCRT5 inhibits Wnt responsive STF16 luciferase (STF16-Luc) with an IC₅₀ of 18 nM. It acts by disrupting the interaction between β-catenin and TCF4,...

    £486 - £1,428
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  • CRANAD-2

    Biovision | CRANAD-2 | 2699

    GRANAD-2 is a near-infrared Aβ plaque-specific fluorescent probe penetrating the blood brain barrier and label senile plaques specifically in vivo. Upon interacting with Aβ aggregates, CRANAD-2 displays a 70-fold increase in fluorescence intensity...

    £508 - £1,526
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  • CPI-613

    Biovision | CPI-613 | 9464

    CPI-613 is a non-redox active lipoate derivative that acts as a selective inhibitor mitochondrial enzymes pyruvate dehydrogenase (PDH) and α-ketoglutarate dehydrogenase. In vitro, CPI-613 dose-dependently and efficiently kills H460 human lung cancer...

    £444 - £1,312
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  • CPI-1189

    Biovision | CPI-1189 | B1306

    CPI-1189 prevents apoptosis and reduces glial fibrillary acidic protein immunostaining in a TNF-alpha infusion model for AIDS dementia complex.CPI-1189 prevents apoptosis and reduces glial fibrillary acidic protein immunostaining in a TNF-alpha infusion...

    £542 - £1,558
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  • CPI-0610

    Biovision | CPI-0610 | B1201

    CPI-0610 is a potent, selective BET (bromodomain and extra terminal family of proteins) inhibitor and inhibits BRD4-BD1 with IC₅₀ of 39 nM. It potentially demonstrates anti-neoplastic activity by binding acetylated lysine recognition motifs on the...

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  • CP-690550 citrate

    Biovision | CP-690550 citrate | 9428

    CP-690550 citrate is the citrate salt of the potent JAK3 inhibitor CP-690550 (Cat. No.1622).CP-690550 citrate is the citrate salt of the potent JAK3 inhibitor CP-690550 (Cat. No.1622).Biovision | 9428 | CP-690550 citrate DataSheetAlternate Name/Synonyms:...

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  • CP-690550

    Biovision | CP-690550 | 1622

    Cell-permeable. A Janus Kinase 3 (JAK3) inhibitor. Displays greater antiproliferative and pro-apoptotic activity against murine multipotent factor-dependent cell Patersen-erythropoietin receptor (FDCP-EpoR) cells harboring JAK2(V617F) compared with...

    £658 - £1,870
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  • CP-640186 hydrochloride

    Biovision | CP-640186 hydrochloride | B1254

    CP-640186 hydrochloride is an isozyme-nonselective acetyl-CoA carboxylase (ACC) inhibitor with IC₅₀ values of 53 nM and 61 nM for rat liver ACC1 and rat skeletal muscle ACC2 respectively.CP-640186 hydrochloride is an isozyme-nonselective acetyl-CoA...

    £542 - £1,656
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  • CP-547632

    Biovision | CP-547632 | B2056

    CP-547,632 is a potent inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and basic fibroblast growth factor (bFGF) with IC₅₀ values of 11 and 9 nM, respectively. Displays anticancer activity.CP-547,632 is a potent inhibitor of the...

    £478 - £708
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  • CP-544326

    Biovision | CP-544326 | B1121

    CP-544326 is a potent selective prostaglandin EP (2) receptor agonist which is the active acid metabolite of the prodrug PF-04217329 (Taprenepag isopropyl). CP-544326 was found to be a potent and selective EP(2) agonist (IC(₅₀) = 10 nM; EC(₅₀) = 2.8 nM)...

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  • CP-31398 Dihydrochloride

    Biovision | CP-31398 Dihydrochloride | 1815

    A styrylquinazoline derivative that acts as a p53 stabilizing agent. It not only restores p53 functions in mutant p53-expressing cells but can also significantly increase the protein level and promote the activity of wild-type p53 in multiple human...

    £478 - £1,362
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  • Coumermycin A1

    Biovision | Coumermycin A1 | B2414

    Coumermycin A1 is a member of the aminocoumarin family of antibiotics that displays antibacterial activity against staphylococci and other gram-positive bacteria and some select gram-negative bacteria. Coumermycin A1 targets the B subunit of the...

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  • Coumarin Boronic acid

    Biovision | Coumarin Boronic acid | B1029

    Coumarin boronic acid (CBA) is a fluorescent probe useful for the detection of peroxynitrite, hypochlorous acid, and hydrogen peroxide. It reacts directly and rapidly with peroxynitrite at a much faster rate (k = 1.1 μM/s) than hydrogen peroxide (k =1.5...

    £606 - £1,918
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  • Concanamycin A

    Biovision | Concanamycin A | B2091

    Concanamycin A is a specific inhibitor of V-type (vacuolar) H+-ATPase. It displays > 2000-fold selectivity over other H+-ATPases (IC₅₀ values are 9.2, > 20000, > 20000 and > 20000 nM for yeast V-type, F-type, P-type H⁺-ATPases and porcine P-type...

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  • Compound W

    Biovision | Compound W | 2208

    Compound W is a γ-secretase inhibitor that has been shown to lower the levels of secreted Aβ42 and Nβ25.Compound W is a γ-secretase inhibitor that has been shown to lower the levels of secreted Aβ42 and Nβ25.Biovision | 2208 | Compound W...

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  • Compound 34

    Biovision | Compound 34 | 1898

    Cell-permeable. A highly potent inhibitor of γ-secretase (IC₅₀ = 0.06 nM)Compound 34 is a highly potent inhibitor of γ-secretase (IC₅₀ = 0.06 nM)Biovision | 1898 | Compound 34 DataSheetAlternate Name/Synonyms:...

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  • Compound 112254

    Biovision | Compound 112254 | 2573

    An adiponectin receptor (AdipoR) agonist. Binds to AdipoR1 and AdipoR2 less potent than AdipoRon (Cat. Nos. 2565 & 2572). Activates 5'-adenosine monophosphate-activated protein kinase (AMPK) in cultured mammalian cells .Improves diabetes, glucose and...

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  • Colistin Sulfate

    Biovision | Colistin Sulfate | 9696

    Colistin sulfate is a potent cationic peptide antibiotic of the polymyxin family that binds to lipids on the cell cytoplasmic membrane of Gram-negativeColistin sulfate is a potent cationic peptide antibiotic of the polymyxin family that binds to lipids...

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  • Coelenterazine-h

    Biovision | Coelenterazine-h | 2742

    Coelenterazine-h is the 2-deoxy derivative of the native Coelenterazine (Cat. No. 2536). Coelentarazine-h produces 10-fold higher light output than native coelentarazine with Renilla luciferase. Coelentarazine-h also undergoes autoluminescence which is...

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  • Coelenterazine, native

    Biovision | Coelenterazine, native | 2536

    Cell-permeable. Coelenterazine is the luminescent substrate for Renilla luciferase and apoaequorin. When coelenterazine combines with luciferase, oxygen, and calcium ions, it produces oxy-coelenterazine and light. This allows coelenterazine to be used...

    £772 - £1,100
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  • CO-1686 (Rociletinib)

    Biovision | CO-1686 (Rociletinib) | 2794

    CO-1686 is an orally bioavailable, irreversible EGFR inhibitor, selectively targeting EGFRL858R/T790M mutant with a Ki value of 21 nM over Wt EGFR (Ki = 303 nM). Displays potent antineoplastic activities.CO-1686 is an orally bioavailable, irreversible...

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  • CMP8

    Biovision | CMP8 | B2328

    A potent and selective mutant ERLBD (Estrogen receptor ligand binding domain) ligand. Cell-permeable.CMP8 is a potent and selective mutant ERLBD (Estrogen receptor ligand binding domain) ligand.Biovision | B2328 | CMP8 DataSheetAlternate Name/Synonyms:...

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  • CMA

    Biovision | CMA | B2397

    CMA is a murine-selective STING agonist (Kd = 3.5 μM). It directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route. CMA triggers type I IFN response in murine macrophages. However, does not activate human STING...

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  • CLP-290

    Biovision | CLP-290 | B1282

    CLP-290 is a novel KCC2 (K(+)-Cl(-) cotransporter isoform 2) modulator and prodrug of CLP-257, that is highly selective for KCC2 over related Cl- transporters.CLP-290 is a novel KCC2 (K(+)-Cl(-) cotransporter isoform 2) modulator and prodrug of CLP-257,...

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  • Clozapine N-oxide

    Biovision | Clozapine N-oxide | B1925

    Clozapine N-oxide is a metabolite of clozapine that activates human muscarinic designer receptors (DREADDs) in vitro.Clozapine N-oxide is a metabolite of clozapine that activates human muscarinic designer receptors (DREADDs) in vitro.Biovision | B1925 |...

    £640 - £1,968
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  • Clonidine hydrochloride

    Biovision | Clonidine hydrochloride | 2684

    Clonidine is an antihypertensive agent that acts as an α2-adrenergic receptor agonist that decreases peripheral vascular resistance by centrally inhibiting sympathetic nerve activity. The antihypertensive effects of clonidine have also been attributed to...

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  • Clindamycin hydrochloride

    Biovision | Clindamycin hydrochloride | 2627

    Clindamycin is a broad spectrum antibiotic targeting primarily gram positive and gram negative bacteria such as Clostridium and Bacteroides species. It inhibits bacterial protein synthesis by binding the 50S ribosomal subunit and interfering with tRNA...

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  • Cimicoxib

    Biovision | Cimicoxib | B1984

    Cimicoxib is an imidazole derivative and a non-steroidal anti-inflammatory drug (NSAID) that acts as a potent and specific cyclooxygenase-2 (COX-2) inhibitor. Used in veterinary medicine to treat dogs for pain and inflammation associated with...

    £806 - £2,622
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