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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • AZD-9291

    Biovision | AZD-9291 | 2674

    AZD-9291 is a potent, third generation, mutant-selective EGFR tyrosine kinase inhibitor. It is effective against both EGFR-TKI sensitizing and resistance T790M mutations. Displays anticancer properties.AZD-9291 is a potent, third generation,...

    $837 - $2,440
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  • AZD-8931

    Biovision | AZD-8931 | 9659

    AZD-8931 is a potent, ATP competitive and reversible inhibitor of EGFR (ErbB-1), Neu (ErbB-2) and ErbB-3 (the IC₅₀ values are 4 nM, 3 nM and 4 nM, respectively).AZD-8931 is a potent, ATP competitive and reversible inhibitor of EGFR (ErbB-1), Neu (ErbB-2)...

    $1,120 - $3,301
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  • AZD8835

    Biovision | AZD8835 | B1661

    AZD8835 is a potent and selective inhibitor of PI3Kδ and PI3Kα with IC50 of 5.7 nM and 6.2 nM, with selectivity against PI3Kβ (IC50 431 nM) and PI3Kγ (IC50 90 nM).AZD8835 is a potent and selective inhibitor of PI3Kδ and PI3Kα with IC50 of 5.7 nM and 6.2...

    $865 - $2,587
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  • AZD-8186

    Biovision | AZD-8186 | B1027

    AZD-8186 is a potent and selective PI3Kβ/δ inhibitor. Displays potential to reduce growth of tumors dependent on dysregulated PTEN for growth.AZD-8186 is a potent and selective PI3Kβ/δ inhibitor. Displays potential to reduce growth of tumors dependent on...

    $1,239 - $4,018
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  • AZD8055

    Biovision | AZD8055 | 2340

    A potent, ATP-competitive inhibitor of mTOR kinase (both mTORC1 and mTORC2) with an IC₅₀ of 0.8 nM. AZD8055 displays excellent selectivity (~ 1,000-fold) against all class I PI3K isoforms and other members of the PI3K-like kinase family. In addition, it...

    $665 - $1,582
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  • AZD-6738

    Biovision | AZD-6738 | B1167

    AZD6738 is a potent ATR kinase inhibitor with IC₅₀ value of 1 nM against the isolated enzyme. AZD6738 selectively inhibits ATR activity by blocking the downstream phosphorylation of the serine/threonine protein kinase CHK1. This prevents ATR-mediated...

    $1,061 - $3,129
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  • AZD-6482

    Biovision | AZD-6482 | B1143

    AZD-6482 is a potent and selective inhibitor of PI 3-kinase β (PI 3-Kβ) (IC₅₀ values are 0.69, 13.6, 47.8 and 136 nM for PI 3-Kβ, PI 3-Kδ, PI 3-Kγ and PI 3-Kα, respectively). It displays 80-fold selectivity for PI3Kβ over PI3k-C2 and DNA-PK and more than...

    $1,120 - $3,584
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  • AZD6244

    Biovision | AZD6244 | 2234

    Cell-permeable. A potent, highly selective and non-ATP competitive inhibitor of mitogen-activated protein kinase kinase 1/2 (MEK1/2) (IC₅₀ = 14 nM/L against purified MEK1). Displays antineoplastic activity.A potent, highly selective and non-ATP...

    $665 - $1,754
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  • AZD-5582

    Biovision | AZD-5582 | B2362

    AZD-5582 is a potent IAP inhibitor that binds potently to the BIR3 domains of cIAP1, cIAP2, and XIAP (IC₅₀ values of 15, 21, and 15 NM, respectively).AZD-5582 is a potent IAP inhibitor that binds potently to the BIR3 domains of cIAP1, cIAP2, and XIAP...

    $718 - $1,985
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  • AZD-5363

    Biovision | AZD-5363 | B1762

    AZD5363, also known as Capivasertib, is a potent pan-AKT kinase inhibitor with IC50 of 3, 7 and 7 nM for Akt1,Akt2 and Akt3, respectively.AZD5363, also known as Capivasertib, is a potent pan-AKT kinase inhibitor with IC50 of 3, 7 and 7 nM for Akt1,Akt2...

    $1,008 - $3,129
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  • AZD-5153

    Biovision | AZD-5153 | B2020

    AZD-5153 is a potent, selective, and orally available BET/BRD4 bromodomain inhibitor with a bivalent binding mode. AZD-5153 ligates two bromodomains in BRD4 simultaneously. Displays cellular and antitumor activity in preclinical hematologic tumor models...

    $1,411 - $4,589
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  • AZD-4635

    Biovision | AZD-4635 | B2012

    AZD-4635 is an orally available, small molecule adenosine A2A receptor antagonist. It reverses adenosine-mediated T-cell suppression and enhances antitumor immunity.AZD-4635 is an orally available, small molecule adenosine A2A receptor antagonist. It...

    $1,239 - $4,018
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  • AZD-4547

    Biovision | AZD-4547 | 9403

    AZD-4547 is a novel and selective inhibitor of the FGFR1, 2, and 3 tyrosine kinases. It binds to and inhibits FGFR, which may result in the inhibition of FGFR-related signal transduction pathways, and thus resulting in the inhibition of tumor cell...

    $837 - $2,440
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  • AZD-3965

    Biovision | AZD-3965 | B2227

    AZD-3965 is a potent and selective monocarboxylate transporter 1 (MCT1) inhibitor with a binding affinity of 1.6 nM; it is 6-fold selective over MCT2 and does not inhibit MCT4 even at 10 μM. AZD 3965 increases intratumor lactate levels and decreases...

    $777 - $2,209
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  • AZD-3759

    Biovision | AZD-3759 | 9609

    AZD-3759 is a potent epidermal growth factor receptor (EGFR) inhibitor, with potential antineoplastic activity. AZD-3759 binds to and inhibits the activity of EGFR as well as certain mutant forms of EGFR. This prevents EGFR-mediated signaling, and may...

    $1,061 - $3,357
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  • AZD-2014

    Biovision | AZD-2014 | 9449

    AZD-2014 is a dual mTORC1/ mTORC2 inhibitor with potential antineoplastic activity.AZD-2014 is a dual mTORC1/ mTORC2 inhibitor with potential antineoplastic activity.Biovision | 9449 | AZD-2014 DataSheetAlternate Name/Synonyms:...

    $949 - $2,898
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  • AZD-1981

    Biovision | AZD-1981 | 9611

    AZD-1981 is a potent and selective antagonist of the chemoattractant receptor-homologous expressed on Th2 lymphocytes receptor (CRTh2 or DP2) with an IC₅₀ value of 4 nM; blocks functional responses in eosinophils, Th2 cells and basophils. It exhibits...

    $1,061 - $3,357
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  • AZD1480

    Biovision | AZD1480 | 2315

    AZD1480 is a novel ATP-competitive inhibitor of JAK1 and JAK2 with IC₅₀ of 1.3 nM and 0.26 nM, respectively.AZD1480 is a novel ATP-competitive inhibitor of JAK1 and JAK2 with IC₅₀ of 1.3 nM and 0.26 nM, respectively.Biovision | 2315 | AZD1480...

    $606 - $1,411
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  • AZD-1283

    Biovision | AZD-1283 | 2838

    AZD-1283 is a potent antagonist of the P2Y12 receptor. In a modified Folts model in dog, AZD-1283 dose-dependently induces increases in blood flow and inhibition of ADP-induced platelet aggregation with antithrombotic ED₅₀ value of 3.0 μg/kg/min.AZD-1283...

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  • AZD-0156

    Biovision | AZD-0156 | B1305

    AZD-0156 is an orally bioavailable Ataxia Telangiectasia Mutated (ATM) kinase inhibitor, with potential chemo-/radio-sensitizing and antineoplastic activities. AZD-0156 targets and binds to ATM, thereby inhibiting the kinase activity of ATM and...

    $949 - $2,727
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  • Azamulin

    Biovision | Azamulin | 2915

    Azamulin is a derivative of the antibiotic pleuromutilin. It is a highly selective inhibitor of the CYP3A family (IC50 = 0.03-0.24 μM as reported in Stresser et al., DMD, January 2004 vol. 32 no. 1 p105-112). Azamulin is a 15 and 13 fold more potent...

    $665 - $1,813
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  • AZ-960

    Biovision | AZ-960 | B2065

    AZ-960 is a potent and specific inhibitor of the JAK2 kinase with a Ki of 0.45 nM. AZ-960 induces growth arrest and apoptosis of human T-cell lymphotropic virus type 1, HTLV-1-infected T cells (MT-1 and MT-2) in parallel with downregulation of the...

    $1,120 - $3,584
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  • AZ-7371

    Biovision | AZ-7371 | B2294

    AZ-7371 is a non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) with an IC₅₀ value of 10 nM. It also inhibits PDE6 (IC₅₀ = 4 µM).AZ-7371 is a non-covalent inhibitor of decaprenylphosphoryl-D-ribose oxidase (DprE1) with an IC₅₀ value...

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  • AZ-6102

    Biovision | AZ-6102 | B1200

    AZ-6102 is a potent TNKS1/2 inhibitor (Tankyrase) that displays >100-fold selectivity against other poly (ADP-ribose) polymerase (PARP) family enzymes and inhibits Wnt pathway with IC₅₀ value of 5 nM in DLD-1 cells. Inhibition of the PARP catalytic...

    $1,120 - $3,413
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  • AZ-505 ditrifluoroacetate

    Biovision | AZ-505 ditrifluoroacetate | B1883

    AZ-505 is a potent and highly selective inhibitor of SMYD2 (IC₅₀ = 0.12 μM) with potential anticancer activity. Displays >600-fold selectivity over other histone methyltransferases, such as SMYD3 (IC₅₀>83.3 μM), DOT1L (IC₅₀>83.3 μM) and EZH2 (IC₅₀>83.3...

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  • AZ-3146

    Biovision | AZ-3146 | B1145

    AZ 3146 is a potent and selective Mps1 (monopolar spindle 1) kinase inhibitor (IC₅₀ = 35 nM). Shows selectivity over 46 other kinases including aurora kinase B and Cdk1. AZ 3146 overrides spindle assembly checkpoint and also interferes with chromosome...

    $1,008 - $3,129
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  • AZ10417808

    Biovision | AZ10417808 | 2786

    AZ10417808 is a selective non-peptide inhibitor of caspase-3 (Ki = 247 nM); displays > 40-fold selectivity over caspases 1, 2, 6, 7 and 8 (Ki > 10 μM). Completely blocks staurosporine-induced intracellular DEVDase activity in SH-SY5Y cells (IC₅₀ = 14.9...

    $718 - $1,985
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  • Axitinib (AG-013736)

    Biovision | Axitinib (AG-013736) | 1581

    Axitinib (also known as AG-013736) is a small molecule tyrosine kinase inhibitor. It inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, PDGFR, and cKIT (CD117). It has been shown to significantly inhibit growth of breast cancer in xenograft...

    $1,036 - $2,065
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  • AVL-292 (Spebrutinib)

    Biovision | AVL-292 (Spebrutinib) | 9413

    AVL-292 is a potent, selective inhibitor of Bruton’s Tyrosine Kinase (BTK) (IC₅₀ = 0. 5 nM) with potential antineoplastic activity.AVL-292 is a potent, selective inhibitor of Bruton’s Tyrosine Kinase (BTK) (IC₅₀ = 0. 5 nM) with potential antineoplastic...

    $777 - $2,209
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  • Avibactam sodium

    Biovision | Avibactam sodium | 9569

    Avibactam (NXL104) is a potent inhibitor of class A and C serine β-lactamases, including KPC carbapenemases. NXL104 quantitatively inhibits BlaC, the only chromosomally encoded β-lactamase from Mycobacterium tuberculosis, by forming a carbamyl adduct...

    $1,351 - $4,246
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  • AV-412 tosylate

    Biovision | AV-412 tosylate | B2052

    AV-412 is a dual EGFR/ErbB2 kinase inhibitor with IC₅₀ values of 43 nM and 282 nM, respectively. Displays anticancer activity.AV-412 is a dual EGFR/ErbB2 kinase inhibitor with IC₅₀ values of 43 nM and 282 nM, respectively. Displays anticancer activity...

    $1,008 - $3,129
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  • Aurantimycin A

    Biovision | Aurantimycin A | 9692

    Aurantimycin A is a depsipeptide antibiotic that acts as a C5a antagonist. Active against Gram-positive bacteria. Displays anti-inflammatory and nematocide activity. Also an antiulcer agent.Aurantimycin A is a depsipeptide antibiotic that acts as a C5a...

    $665 - $1,754
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  • AT-7519 hydrochloride

    Biovision | AT-7519 hydrochloride | 2816

    AT-7519 is a potent CDK inhibitor with potential antineoplastic activity. AT-7519 displays potent antiproliferative activity (40-940 nM) in a panel of human tumor cell lines, and the mechanism of action is shown to be consistent with the inhibition of...

    $837 - $2,440
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  • AT-406

    Biovision | AT-406 | B1829

    AT-406 is a potent inhibitor of IAP (inhibitor of apoptosis protein) family of proteins with potential apoptotic inducing and antineoplastic activity. AT-406 selectively inhibits the biological activity of IAP proteins, including X chromosome-linked IAP...

    $1,411 - $4,732
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  • AT-13387

    Biovision | AT-13387 | B1961

    AT-13387 is a synthetic, orally bioavailable and small-molecule inhibitor of heat shock protein 90 (Hsp90) with IC₅₀ value of 18 nM in A375 cells. Hsp90 acts as a “molecular chaperone” stabilizing and preventing the breakdown of key cancer-forming...

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  • AT-13148

    Biovision | AT-13148 | B1144

    AT13148 is a potent, ATP-competitive multi-AGC kinase inhibitor that displays antitumor activity. AT13148 blocks AKT, p70S6K, PKA, ROCK, and SGK substrate phosphorylation inducing concentration dependent apoptosis in cancer cells. It also shows...

    $1,152 - $3,584
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  • AT-101

    Biovision | AT-101 | 2380

    AT-101 is the R-(-) enantiomer of Gossypol that acts as an inhibitor of the antiapoptotic Bcl proteins (Bcl-2, Bcl-XL, Bcl-W, and Mcl-1) and an inducer of the pro-apoptotic proteins noxa and puma. It induces apoptosis in drug-resistant multiple myeloma...

    $889 - $2,699
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  • AT 56

    Biovision | AT 56 | 2592

    AT-56 is a selective, competitive, and highly bioavailable inhibitor of L-PGDS (lipocalin-type prostaglandin D synthase) (Ki = 75 µM). It inhibits the production of PGD2 by L-PGDS purified from human CSF and recombinant mouse cells with an IC₅₀ value of...

    $1,239 - $2,499
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  • Aspterric acid

    Biovision | Aspterric acid | B2233

    Aspterric acid is an antibiotic that acts as a plant growth regulator.Aspterric acid is an antibiotic that acts as a plant growth regulator.Biovision | B2233 | Aspterric acid DataSheetAlternate Name/Synonyms: CCG-102628Appearance: White solidFormulation:...

    $1,985 - $6,570
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  • ASP-3026

    Biovision | ASP-3026 | B1296

    ASP-3026 is a potent, and ATP-competitive inhibitor of ALK (Anaplastic Lymphoma Receptor Tyrosine Kinase) with IC₅₀ value of 3.5 nM. It also inhibits ROS (IC₅₀ = 8.9 nM) and ACK (IC₅₀ = 5.8 nM). ASP3026 has been shown to overcome Crizotinib (Cat. No...

    $949 - $2,727
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  • ASB-16

    Biovision | ASB-16 | 2136

    A zwitterionic detergent useful for the solubilization of proteins including previously undetected membrane proteins. ASB-16 exhibits better protein solubilization properties than CHAPS. Also useful for solubilizing proteins for 2D-gel electrophoresis...

    $809 - $1,925
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  • ASB-14

    Biovision | ASB-14 | 1738

    A zwitterionic detergent useful for the solubilization of proteins including previously undetected membrane proteins. ASB-14 exhibits better protein solubilization properties than CHAPS. Also useful for solubilizing proteins for 2D-gel electrophoresis...

    $1,351 - $4,533
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  • AS-2444697 Hydrochloride

    Biovision | AS-2444697 Hydrochloride | B1585

    AS-2444697 is a potent and selective interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitor (IC₅₀ = 21 nM). It exhibits 30-fold selectivity for IRAK4 over IRAK1. Inhibits LPS-induced TNF-α and IL-6 production in PBMCs in vitro.AS-2444697 is a...

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  • AS-041164

    Biovision | AS-041164 | B1870

    AS-041164 is a potent, ATP-competitive, and isoform-selective PI3-Kinase inhibitor (IC₅₀ = 0.07, 0.24, 1.45, and 1.70 μM for the γ, α, β, and δ isoforms respectively).AS-041164 is a potent, ATP-competitive, and isoform-selective PI3-Kinase inhibitor...

    $837 - $2,440
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  • AS 604850

    Biovision | AS 604850 | 2339

    Cell-permeable. A selective, ATP-competitive inhibitor of PI3Kγ with IC50 values of 0.25, >20, >20, and 4.5 µM for the human recombinant γ, δ, β, and α isoforms, respectively. AS 604850 inhibits MCP-1-mediated monocyte chemotaxis with an IC50 value of 21...

    $637 - $1,463
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  • AS 602801

    Biovision | AS 602801 | B1687

    AS 602801 is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively.AS 602801 is an ATP-competitive JNK inhibitor with IC50 of 80 nM, 90 nM, and 230 nM for JNK1, JNK2, and JNK3, respectively...

    $1,152 - $3,556
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  • ARN-509

    Biovision | ARN-509 | 9535

    ARN-509 is a selective and competitive androgen receptor (AR) inhibitor (IC₅₀ = 16 nM). ARN-509 selectively binds the androgen receptor and impairs its nuclear translocation and DNA binding to androgen response elements useful for prostate cancer...

    $949 - $2,898
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  • AR-42 (HDAC-42)

    Biovision | AR-42 (HDAC-42) | 2716

    AR-42 is a potent histone deacetylase inhibitor (HDACi). It induces growth inhibition, cell- cycle arrest, apoptosis, and activation of caspases-3/7. AR-42 also promotes hyperacetylation of H3, H4, and alpha-tubulin, and up-regulation of p21 and exhibits...

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  • APY-0201

    Biovision | APY-0201 | 9564

    APY0201 is a potent, highly selective, ATP-competitive PIKfyve inhibitor (IC₅₀ = 5.2 nM) that interrupts the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3,5)P2. Also acts as a unique small molecular IL-12/23 production inhibitor...

    $1,008 - $3,129
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  • Apramycin Sulfate

    Biovision | Apramycin Sulfate | B1521

    Apramycin is an aminoglycoside antibiotic that binds the deep groove of RNA and effectively inhibits ribosomal translocation blocking protein synthesis. Displays bactericidal activity against most gram-negative bacteria.Apramycin is an aminoglycoside...

    $620 - $1,582
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  • Apoptosis inhibitor

    Biovision | Apoptosis inhibitor | 2783

    Apoptosis Inhibitor is a cell-permeable inhibitor of apoptosis induction. It does not directly inhibit caspase-3, but effects are attributable to the inhibition of caspase-3 activation.Apoptosis Inhibitor is a cell-permeable inhibitor of apoptosis...

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