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Reagents

A substance which is used as a chemical reaction or it is a test reactions occurs. A reagents is to measure the chemical substance is present or not because reagents is the components or a mixture. A chemical reagents works like a detectives which charged and point out the other substance in chemical reactions. For making a reagents the equal number of volumes solutions A and B use immediately and then it is used as a reagents.1.5g of ferric chloride and 2.0g of potassium thiocynate in 100 ml water to dissolve after that make saturated solution in 50% ethnol.

The reagents take action when solvents involved in the reaction which are usually called reactants but catalysts are not consumed with the reactions hence they are not reactants. Iodine is not soluble in water therefore the iodine reagents is made in dissolving the water with a helps of potassium iodide.

  • Apoptosis activator 2

    Biovision | Apoptosis activator 2 | 2784

    Apoptosis activator 2 is a cell-permeable apoptosis activator that promotes the cytochrome c-dependent oligomerization of Apaf-1 into the mature apoptosome. Increases procaspase-9 processing and subsequent caspase-3 activation. Induces apoptosis in tumor...

    £444 - £1,262
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  • Apilimod mesylate

    Biovision | Apilimod mesylate | B1129

    Apilimod is a small molecule that inhibits IL-12 and IL-23 production - cytokines that are involved in autoimmune diseases through the prevention of nuclear translocation of c-Rel. It suppresses the Th1, but not the Th2, response, resulting in reduced...

    £542 - £1,656
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  • APD-597

    Biovision | APD-597 | 9637

    APD-597 is a GPR119 agonist with EC₅₀ of 46 nM for hGPR119. Could be a potential anti-diabetic agent for treatment of type 2 diabetes.APD-597 is a GPR119 agonist with EC₅₀ of 46 nM for hGPR119. Could be a potential anti-diabetic agent for treatment of...

    £640 - £2,048
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  • Apatinib mesylate

    Biovision | Apatinib mesylate | B1608

    Apatinib mesylate is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitorApatinib mesylate is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitorBiovision | B1608 | Apatinib mesylate DataSheetAlternate...

    £640 - £1,968
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  • Apatinib (Free base)

    Biovision | Apatinib (Free base) | B1613

    Apatinib is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential antiangiogenic and antineoplastic activitiesApatinib is an orally bioavailable, small-molecule receptor tyrosine kinase inhibitor with potential...

    £444 - £1,262
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  • Antipain dihydrochloride

    Biovision | Antipain dihydrochloride | 2834

    Antipain is a reversible protease inhibitor that inhibits cathepsin A, B, and D as well as papain, trypsin and trypsin-like serine proteases. Antipain is more specific for papain and trypsin than is leupeptin (Cat. No. 1648). The inhibitory potency of...

    £380 - £1,002
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  • Antimycin A

    Biovision | Antimycin A | 2247

    Antimycin A, isolated from Streptomyces sp., is a mixture of Antimycins A1, A2, A3 and A4. Inhibits mitochondrial electron transport, specifically between cytochromes b and c1. Induces apoptosis, which is not prevented by the presence of Bcl-2.Antimycin...

    £410 - £920
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  • Anlotinib, free base

    Biovision | Anlotinib, free base | B2156

    Anlotinib (AL3818) is a novel multitarget tyrosine kinase inhibitor, inhibiting tumor angiogenesis and proliferative signaling. Potential antineoplastic and anti-angiogenic agent.Anlotinib (AL3818) is a novel multitarget tyrosine kinase inhibitor,...

    £576 - £1,788
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  • AN-2728

    Biovision | AN-2728 | B2220

    AN-2728 is a boron-based, topical anti-inflammatory agent that acts as a phosphodiesterase 4 (PDE4) inhibitor (IC₅₀ = 0.11 µM). It is less potent against PDE1A, PDE3A, and PDE7A (IC₅₀s = 6.12, 6.41, and 0.73 µM, respectively). AN-2728 suppresses the...

    £410 - £1,134
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  • AMPK Activator, D942

    Biovision | AMPK Activator, D942 | 2341

    Cell-permeable. A potent activator of AMPK (AMP-activated protein kinase). The activation of AMPK was achieved through inhibition of NAD(P)H dehydrogenase [quinone] 1 (complex I). D942 increases glucose uptake in L6 myocytes, and inhibits CCL2-induced...

    £364 - £836
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  • Ampicillin trihydrate

    Biovision | Ampicillin trihydrate | 2483

    A β-lactam antibiotic structurally related to penicillin. Inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Ampicillin can be used as a selective agent in several types of...

    £410 - £2,048
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  • Ampicillin sodium

    Biovision | Ampicillin sodium | 2484

    Ampicillin sodium is a β-lactam antibiotic structurally related to penicillin. Inhibits bacterial cell-wall synthesis by inactivating transpeptidases on the inner surface of the bacterial cell membrane. Ampicillin sodium can be used as a selective agent...

    £410 - £1,722
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  • Amphotericin B, USP

    Biovision | Amphotericin B, USP | 2497

    A polyene antifungal antibiotic from Streptomyces. Amphotericin B targets a wide range of susceptible fungi including Histoplasma, Coccidioides, and Cryptococcus species. Amphotericin B targets ergosterol in the fungal cell membrane and increases...

    £478 - £3,426
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  • AMMC iodide

    Biovision | AMMC iodide | 2873

    AMMC iodide is a useful substrate for the human cytochrome P450 CYP2D6 isozyme. It is demethylated to the fluorescent product 3-[2-(N,N-diethyl-N-methyl ammonium)ethyl]-7-hydroxy-4-methylcoumarin (AMHC). After the AMMC is hydrolyzed, the pH is increased...

    £1,082 - £3,508
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  • Amlodipine besylate

    Biovision | Amlodipine besylate | 2378

    A L-type calcium channel blocker and an anti-hypertensive agent. Amlodipine displays vasoprotective effects in cardiovascular disease and inhibits Ca²⁺-induced contractions in depolarized rat aorta (IC₅₀ = 1.9 nM). Amlodipin also inhibits proliferation...

    £410 - £1,100
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  • Amiodarone Hydrochloride

    Biovision | Amiodarone Hydrochloride | 1828

    A non-selective ion channel blocker with broad fungicidal activity. Amiodarone induces an immediate influx of Ca2+ in Saccharomyces cerevisiae, followed by mitochondrial fragmentation and cell death. Also acts as an autophagy inducer.Amiodarone...

    £394 - £1,036
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  • Aminopurvalanol A

    Biovision | Aminopurvalanol A | 2205

    A cell-permeable, reversible and competitive inhibitor of cyclin-dependent kinases. IC₅₀ values are: CDK1/cyclin B (33 nM), CDK2/cyclin A (33 nM), CDK2/cyclin E (28 nM) and CDK5/p35 (20 nM).Aminopurvalanol A is a cell-permeable, reversible and...

    £364 - £920
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  • Amikacin Disulfate

    Biovision | Amikacin Disulfate | B1513

    Semisynthetic, aminoglycoside antibiotic derived from Kanamycin A. Range of activity is similar to Gentamicin. Active against many strains of Gram negative bacteria. Amikacin prevents bacterial protein synthesis by binding to the 30S ribosome subunit and...

    £410 - £3,426
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  • Amikacin

    Biovision | Amikacin | B1514

    Amikacin is an aminoglycoside antibiotic used to treat different types of bacterial infections. Amikacin works by binding to the bacterial 30S ribosomal subunit, causing misreading of mRNA and leaving the bacterium unable to synthesize proteins vital to...

    £380 - £1,690
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  • Amidepsine D, Humcola sp.

    Biovision | Amidepsine D, Humcola sp. | 2148

    An inhibitor of diacylglycerol acyltransferase (DGAT). Shows inhibitory effect in rat liver microsomes (IC₅₀ = 17.5 µM) and Raji cells (IC₅₀ = 2.8µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and...

    £870 - £1,526
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  • Amidepsine A, Humcola sp.

    Biovision | Amidepsine A, Humcola sp. | 2147

    A diacylglycerol acyltransferase (DGAT) inhibitor. Shows inhibitory effect in rat liver microsomes (IC₅₀ = 10.2 µM) and Raji cells (IC₅₀ = 15.5 µM). Excessive accumulation of triacetylglycerol produced by DGAT may cause fatty liver, obesity and...

    £870 - £1,526
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  • AMI-5

    Biovision | AMI-5 | 2300

    AMI-5 is a non-specific small molecule inhibitor of protein arginine methyltransferases (PRMTs) (IC₅₀ = 0.78 and 1.41 µM against Hmt1p and PRMT1, respectively) and histone lysine methyltransferases (HKMTs) (DOT1 and SET7, but not Suv39H1 and Suv39H2)...

    £410 - £1,002
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  • AMG-Tie2

    Biovision | AMG-Tie2 | B1612

    AMG-Tie2 is a highly potent, non-selective inhibitor of Tie-2AMG-Tie2 is a highly potent, non-selective inhibitor of Tie-2Biovision | B1612 | AMG-Tie2 DataSheetAlternate Name/Synonyms: AMGTie2; AMG Tie2;...

    £738 - £2,214
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  • AMG-925

    Biovision | AMG-925 | B1959

    AMG-925 is a potent and orally bioavailable dual FLT3/CDK4 inhibitor with IC₅₀ of 1 nM and 3 nM, respectively. It inhibits the proliferation of a panel of human tumor cell lines including Colo205 (Rb(+)) and U937 (FLT3(WT)) and induces cell death in...

    £576 - £1,788
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  • AMG-900

    Biovision | AMG-900 | B1343

    AMG-900 is a highly sensitive and orally bioavailable inhibitor of Aurora Kinase with IC50 values of 5 nmol/LAMG-900 is a highly sensitive and orally bioavailable inhibitor of Aurora Kinase with IC50 values of 5 nmol/LBiovision | B1343 | AMG-900...

    £1,232 - £4,670
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  • AMG-232

    Biovision | AMG-232 | 9556

    AMG232 is a highly potent MDM2 inhibitor (SPR KD = 0.045 nM, SJSA-1 EdU IC₅₀ = 9.1 nM), with remarkable pharmacokinetic properties and in vivo antitumor activity in the SJSA-1 osteosarcoma xenograft model (ED₅₀ = 9.1 mg/kg).AMG232 is a highly potent MDM2...

    £428 - £1,214
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  • Ambroxol hydrochloride

    Biovision | Ambroxol hydrochloride | 9688

    Ambroxol is a sodium channel blocker and mucolytic agent with antioxidant, anti-viral and anti-inflammatory properties. Inhibits tetrodotoxin (TTX)-resistant channels more potently than TTX-sensitive subtypes (IC₅₀ values for tonic block are 35.2 and 111...

    £444 - £806
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  • AM-095

    Biovision | AM-095 | 9581

    AM-095 is a potent LPA1 receptor antagonist with IC₅₀ values of 0.98 and 0.73 μM for recombinant human and mouse LPA1, respectively. In functional assays, AM-095 inhibitsLPA-driven chemotaxis of CHO cells overexpressing mouse LPA₁ (IC₅₀ = 778 nM) and...

    £576 - £1,788
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  • Altenusin, Penicillium sp.

    Biovision | Altenusin, Penicillium sp. | 2146

    Sphingomyelinase (N-SMase) and strong pp60c-Src inhibitor. Inhibits cFMS receptor tyrosine kinase (CSF-1/m-CSF receptor tyrosine kinase) which is implicated in cancer and bone diseases. Myosin light chain kinase inhibitor. Also exhibits anti-HIV-1...

    £870 - £3,392
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  • Alsterpaullone

    Biovision | Alsterpaullone | 1897

    Cell-permeable. A potent inhibitor of CDK1/cyclin B (IC₅₀ =35 nM). Also inhibits CDK2/cyclin A, CDK2/cyclin E (IC₅₀ = 200 nM), CDK5/p25 (IC₅₀ = 40 nM), CDK5/p35 (IC₅₀ = 40 nM) and GSK-3β.Alsterpaullone is a potent inhibitor of CDK1/cyclin B (IC₅₀ =35 nM)...

    £478 - £1,362
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  • Alendronate sodium

    Biovision | Alendronate sodium | 2168

    Alendronate sodium is a bisphosphonate that acts as a specific inhibitor of osteoclast-mediated bone resorption. It inhibits bone resorption in vitro with an IC₅₀ value of 2 nM. Also acts as a farnesyl diphosphate synthase inhibitor (IC₅₀ = 460 nM) and...

    £394 - £1,066
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  • Aldosterone

    Biovision | Aldosterone | B2153

    Aldosterone is a steroid hormone produced by the outer portion (cortex) of the adrenal gland and its secretion is regulated by the renin-angiotensin system. It plays an important role in cardiovascular health and can be a cause of endocrine hypertension...

    £738 - £2,444
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  • Akt-I-1

    Biovision | Akt-I-1 | B1610

    Akt-I-1 is a specific inhibitor of Akt1 (IC(50) 4.6 µM) and does not inhibit AKT2, or AKT3Akt-I-1 is a specific inhibitor of Akt1 (IC(50) 4.6 µM) and does not inhibit AKT2, or AKT3Biovision | B1610 | Akt-I-1 DataSheetAlternate Name/Synonyms: Akt-I-1;...

    £576 - £1,722
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  • Akt Inhibitor (10-NCP)

    Biovision | Akt Inhibitor (10-NCP) | 2338

    Cell-permeable. A reversible and specific inhibitor of Akt activity in vitro (complete inhibition at < 5 µM). Displays minimal effect on PI 3-K, PDK1, or SGK1. Blocks IGF-I stimulated nuclear translocation of Akt in Rh1 cells and suppressed growth of...

    £444 - £1,066
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  • AKR1C3 Inhibitor III

    Biovision | AKR1C3 Inhibitor III | 2424

    A highly potent and selective inhibitor of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3 (IC₅₀ = 88 nM). Displays >100-fold selectivity against AKR1C1, AKR1C2 and AKR1C4. Does not display any COX (cyclooxygenase) inhibition at 10 µM in whole blood...

    £478 - £1,330
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  • AKR1C3 Inhibitor II

    Biovision | AKR1C3 Inhibitor II | 2404

    A highly potent and selective inhibitor of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3 (IC₅₀ = 94 nM). Displays much weaker inhibitory activity against AKR1C1, AKR1C2 and AKR1C4 (IC₅₀ >30 µM). Does not display any COX (cyclooxygenase) inhibition...

    £542 - £1,558
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  • AKR1C3 Inhibitor I

    Biovision | AKR1C3 Inhibitor I | 2403

    A highly potent and selective inhibitor of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3. In repeat assays it showed an IC₅₀ of 0.013 ± 0.003 μM for AKR1C3, compared with 20.3 ± 3.8 μM against AKR1C1 and >30 μM against AKR1C2 and AKR1C4. This...

    £478 - £1,330
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  • AKP-11

    Biovision | AKP-11 | B1973

    AKP-11 is a novel S1P1 (Sphingosine-1-phosphate receptor 1) agonist with potential therapeutic potential for treatment of MS and related autoimmune disorders.AKP-11 is a novel S1P1 (Sphingosine-1-phosphate receptor 1) agonist with potential therapeutic...

    £738 - £2,444
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  • AICA riboside, 5'-phosphate

    Biovision | AICA riboside, 5'-phosphate | 9416

    AICAR monophosphate is a 5′-phosphorylated analog of cell-permeable AICAR (Cat. No.1687) that mimics AMP and acts as an activator of AMPK (AMP-activated protein kinase); displays enhanced water solubility compared to AICAR.AICAR monophosphate is a...

    £478 - £1,394
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  • AHU-377

    Biovision | AHU-377 | 9520

    AHU-377 is a prodrug that is activated in vivo by esterases to form an active compound LBQ657 which acts as a potent and selective neprilysin inhibitor. Neprilysin is a protease responsible for the degradation of atrial and brain natriuretic peptides...

    £542 - £1,656
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  • Agistatin E

    Biovision | Agistatin E | B1023

    Agistatin E is a tricyclic analog of Agistatin A. Acts as a cholesterol biosynthesis inhibitor. Mycotoxin.Agistatin E is a tricyclic analog of Agistatin A. Acts as a cholesterol biosynthesis inhibitor. Mycotoxin.Biovision | B1023 | Agistatin E...

    £756 - £2,444
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  • Agistatin D

    Biovision | Agistatin D | B1022

    Agistatin D is a cholesterol biosynthesis inhibitor. Isolated from fungus A 6239.Agistatin D is a cholesterol biosynthesis inhibitor. Isolated from fungus A 6239.Biovision | B1022 | Agistatin D DataSheetAlternate Name/Synonyms:...

    £756 - £2,444
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  • Agistatin B

    Biovision | Agistatin B | B1021

    Agistatin B is a cholesterol biosynthesis inhibitor. Isolated from fungus FH-A 6239.Agistatin B is a cholesterol biosynthesis inhibitor. Isolated from fungus FH-A 6239.Biovision | B1021 | Agistatin B DataSheetAlternate Name/Synonyms:...

    £756 - £2,444
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  • AG-881

    Biovision | AG-881 | B1953

    AG-881 is a potent and selective inhibitor of mutated forms of both isocitrate dehydrogenase type 1 (IDH1, IDH1 [NADP+] soluble) in the cytoplasm and type 2 (IDH2, isocitrate dehydrogenase [NADP⁺], mitochondrial) in the mitochondria, with potential...

    £478 - £1,394
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  • AG-221 (Enasidenib)

    Biovision | AG-221 (Enasidenib) | B1070

    AG-221(Enasidenib) is a potent, selective, and reversible inhibitor of mutant IDH2 (isocitrate dehydrogenase type 2). It specifically inhibits IDH2 in the mitochondria, blocking the formation of oncometabolite 2-hydroxyglutarate (2HG). In in vitro...

    £542 - £1,656
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  • AG-120 (Ivosidenib)

    Biovision | AG-120 (Ivosidenib) | B1163

    AG-120 is a potent isocitrate dehydrogenase type 1 (IDH1) inhibitor, with potential antineoplastic activity. Upon oral administration it specifically inhibits a mutated form of IDH1 in the cytoplasm inhibiting the formation of oncometabolite,...

    £444 - £1,262
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  • AG-014699 phosphate

    Biovision | AG-014699 phosphate | 2890

    AG-014699 phosphate is a potent, cell-permeable inhibitor of PARP1 with Ki of 1.4 nM. It selectively binds to PARP 1 and inhibits the PARP1-mediated DNA repair, thus potentiating the genomic instability and apoptosis. Displays antineoplastic activity...

    £410 - £1,134
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  • AG 1478

    Biovision | AG 1478 | 1800

    Cell-permeable. A potent EGFR Tyrosine Kinase (TK) inhibitor with an IC₅₀ of 3 nM. Only weakly inhibits PDGFR and HER2-NEU kinases (IC₅₀ >100 µM).AG 1478 is a potent EGFR Tyrosine Kinase (TK) inhibitor with an IC₅₀ of 3 nM. Only weakly inhibits PDGFR and...

    £542 - £1,558
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