Reagents

Biovision | EZSolution™ TAPI-1 | 2537

Inhibitor of TNF-α processing (IC₅₀ = 100 nM), similar to TAPI-0 (Cat. No. 2067-1), but more stable in tissue culture and in vivo. Inhibits TACE and other metalloproteases. Blocks release of TNF- α (IC₅₀ = 50-100 μM), APP (1-8 μM), IL6R (5- 10 μM), TNFRI...

Biovision | EZSolution™ Sunitinib Malate | 1804

A 100 mM (25 mg in 469.4 µl) solution of Sunitinib Malate (Cat. No. 1611-25) in anhydrous DMSO.EZSolution™ Sunitinib Malate is a 100 mM (25 mg in 469.4 µl) solution of Sunitinib Malate (Cat. No. 1611-25) in anhydrous DMSO.Biovision | 1804 | EZSolution™...

Biovision | EZSolution™ SU-5416 | 9492

A 10 mM (5 mg in 2098 µl) of the VEGFR kinase inhibitor SU-5416 (Cat. No. 9491) in anhydrous DMSO.SU-5416 is a potent tyrosine kinase inhibitor best known as an inhibitor of the vascular endothelial growth factor receptor (VEGFR-2; Flk-1/KDR). In...

Biovision | EZSolution™ SU-5402 | 2017

A 10 mM (500 µg/169 µl) solution of SU5402 (Cat. No. 1645) in anhydrous DMSO.EZSolution™ SU-5402 is a 10 mM (500 µg/169 µl) solution of SU5402 (Cat. No. 1645) in anhydrous DMSO.Biovision | 2017 | EZSolution™ SU-5402 DataSheetAlternate Name/Synonyms:...

Biovision | EZSolution™ StemRegenin 1, Free base | 2643

A 10 mM (1 mg in 233 µl) of the stem cell fate modulator StemRegenin 1 (Cat. No. 2642) in anhydrous DMSOStemRegenin 1 (SR1) is a cell-permeable purine derivative that acts as an antagonist of aryl hydrocarbon receptor and promotes the self-renewal of...

Biovision | EZSolution™ Staurosporine | 1745

A 1 mM (100 µg/214 µl) solution of Staurosporine (Cat. No. 1048-01) in DMSO.EZSolution™ Staurosporine is a 1 mM (100 µg/214 µl) solution of Staurosporine (Cat. No. 1048-01) in DMSO.Biovision | 1745 | EZSolution™ Staurosporine DataSheetAlternate...

Biovision | EZSolution™ Stattic, Sterile-filtered | B2241

A 10 mM (5 mg in 2.37 ml), sterile-filtered solution of the STAT3 activation inhibitor Stattic (Cat. No. 2625) in anhydrous DMSO.EZSolution™ Stattic is a 10 mM (5 mg in 2.37 ml), sterile-filtered solution of the STAT3 activation inhibitor Stattic (Cat...

Biovision | EZSolution™ Stat3 Inhibitor I, S3I-201 | 2541

Inhibits Stat3.Stat3 complex formation and Stat3-DNA binding activity in vitro (IC₅₀ = 86 ± 33 µM) and Stat3-dependent transcriptional activities. S3I-201 inhibits the expression of the Stat3-regulated genes encoding cyclin D1, Bcl-xL, and survivin and...

Biovision | EZSolution™ SP600125 | 9541

A 10 mM (5 mg in 2270 µl) of the JNK inhibitor SP600125 (Cat. No.1669) in anhydrous DMSO.U0126 is a potent and selective non-competitive inhibitor of MAP kinase kinase(MEK). Inhibits MEK-1 and MEK-2 (IC₅₀ values of 0.07 and 0.06 µM respectively) with...

Biovision | EZSolution™ SCR7 pyrazine | B1877

A 10 mM (5.0 mg in 1.50 ml), sterile-filtered solution of the HDR (homology-directed repair) enhancer SCR7 Pyrazine (Cat. No. B1119) in anhydrous DMSO.SCR7 pyrazine is a potent inhibitor of nonhomologous endjoining (NHEJ) mediated by DNA ligase IV...

Biovision | EZSolution™ SCD1 Inhibitor | 2548

Cell-permeable. A potent and selective inhibitor of SCD1(stearoyl-CoA desaturase 1) (In vitro: IC₅₀ = 37 nM for hSCD1,

Biovision | EZSolution™ SB-525334 | 2881

A 10 mM (5 mg in 1456 µl) of the ALK5 inhibitor SB-525334 (Cat. No. 2880) in anhydrous DMSO.SB-525334 is a potent and selective inhibitor of transforming growth factor-β receptor I (ALK5, TGF-βRI) (IC₅₀ = 14.3 nM); displays 4-fold less potency against...

Biovision | EZSolution™ SB-431542, Sterile-Filtered | 1992

A 5 mM (1.92 mg in 1 ml), sterile-filtered solution of the ALK5 inhibitor SB-431542 (Cat. No. 1674) in anhydrous DMSO.EZSolution™ SB-431542, Sterile-Filtered is a 5 mM (1.92 mg in 1 ml), sterile-filtered solution of the ALK5 inhibitor SB-431542 (Cat. No...

Biovision | EZSolution™ SB-431542 | 1872

A 10 mM (1 mg in 260 µl) solution of SB-431542 (Cat. No. 1674-1) in anhydrous DMSO.EZSolution™ SB-431542 is a 10 mM (1 mg in 260 µl) solution of SB-431542 (Cat. No. 1674-1) in anhydrous DMSO.Biovision | 1872 | EZSolution™ SB-431542 DataSheetAlternate...

Biovision | EZSolution™ SB 203580 | 1786

A 10 mM (1 mg in 265 µl) solution of SB 203580 (Cat. No. 1712-1) in anhydrous DMSO.EZSolution™ SB 203580 is a 10 mM (1 mg in 265 µl) solution of SB 203580 (Cat. No. 1712-1) in anhydrous DMSO.Biovision | 1786 | EZSolution™ SB 203580 DataSheetAlternate...

Biovision | EZSolution™ SAG, Sterile-filtered | B2239

A 5 mM (2.45 mg in 1 ml), sterile-filtered solution of the Smo agonist SAG (Cat. No. 1939) in anhydrous DMSO.EZSolution™ SAG is a 5 mM (2.45 mg in 1 ml), sterile-filtered solution of the Smo agonist SAG (Cat. No. 1939) in anhydrous DMSO.Biovision | B2239...

Biovision | EZSolution™ RS-1 | B1876

A 10 mM (5.0 mg in 954 μl), sterile-filtered solution of the HDR (homology-directed repair) enhancer RS-1 (Cat. No. B1118) in anhydrous DMSO.RS-1 (RAD51-stimulatory compound 1) is a high affinity stimulator of the human homologous recombination (HR)...

Biovision | EZSolution™ Rosuvastatin | 2806

A 10 mM (5 mg in 1038 µl) of the HMG-CoA inhibitor Rosuvastatin (Cat. No. 1955) in anhydrous DMSO.Rosuvastatin belongs to a class of compounds called statins that is used to reduce plasma cholesterol levels and prevent cardiovascular disease. It...

Biovision | EZSolution™ Rolipram, Sterile-filtered | B2250

A 10 mM (5 mg in 1.82 ml), sterile-filtered solution of the phosphodiesterase-4 (PDE4) inhibitor Rolipram (Cat. No. 2010) in anhydrous DMSO.EZSolution™ Rolipram is a 10 mM (5 mg in 1.82 ml), sterile-filtered solution of the phosphodiesterase-4 (PDE4)...

Biovision | EZSolution™ RG7388 | B1504

A 10 mM (1 mg in 162 μl) solution of the p53-MDM2 interaction inhibitor RG7388 (Cat. No. 2577) in anhydrous DMSO.RG7388 is highly a potent and selective inhibitor of p53-MDM2 interaction. RG7388 blocks p53−MDM2 binding and effectively activates the p53...

Biovision | EZSolution™ RG-108, Sterile-filtered | B2238

A 10 mM (5.0 mg in 1.50 ml), sterile-filtered solution of the DNA methyltransferase (DNMT) inhibitor RG-108 (Cat. No. 1679) in anhydrous DMSO.EZSolution™ RG-108 is a 10 mM (5.0 mg in 1.50 ml), sterile-filtered solution of the DNA methyltransferase (DNMT)...

Biovision | EZSolution™ RepSox | 2641

A 10 mM (5 mg in 1740 µl) of the ALK5 inhibitor RepSox (Cat. No. 1894) in anhydrous DMSO.RepSox is a TGF-β type I receptor (ALK5) inhibitor. Inhibits ALK5 autophosphorylation (IC₅₀ = 4 nM). Can replace one of the four reprogramming factors Sox-2...

Biovision | EZSolution™ Raptinal | 9652

A 10 mM (5 mg in 1294 µl) of the rapid apoptosis inducer Raptinal (Cat. No. 9626) in anhydrous DMSO.Raptinal is a rapid inducer of apoptosis. Consistent with apoptotic morphological changes, U-937 cells treated with 10 μM Raptinal displays modest (at 30...

Biovision | EZSolution™ Rapamycin | 1746

A 5 mM (5 mg in 1093 µl) solution of Rapamycin (Cat. No. 1568-5) in DMSO.EZSolution™ Rapamycin is a 5 mM (5 mg in 1093 µl) solution of Rapamycin (Cat. No. 1568-5) in DMSO.Biovision | 1746 | EZSolution™ Rapamycin DataSheetAlternate Name/Synonyms:...

Biovision | EZSolution™ Q-VD-OPh, Negative Control | 1174

A 10 mM (1 mg in 190 µl) solution of the negative control Q-VE-OPh (Cat. No, 1171-1) for the caspase inhibitor Q-VD-OPh (Cat. No. 1170-1) in DMSO.EZSolution™ Q-VD-OPh, Negative Control is a 10 mM (1 mg in 190 µl) solution of the negative control Q-VE-OPh...

Biovision | EZSolution™ Q-VD-OPh | 1173

A 10 mM (1 mg in 195 µl) solution of caspase inhibitor Q-VD-OPh (Cat. No, 1170-1) in DMSO.EZSolution™ Q-VD-Oph is a 10 mM (1 mg in 195 µl) solution of caspase inhibitor Q-VD-OPh (Cat. No, 1170-1) in DMSO.Biovision | 1173 | EZSolution™ Q-VD-OPh...

Biovision | EZSolution™ Q-DEVD-OPh | 1178

A 10 mM (1 mg in 125 μl) solution of caspase-3 inhibitor Q-DEVD-OPh (Cat. No. 1175-1) in DMSO.EZSolution™ Q-DEVD-Oph is a 10 mM (1 mg in 125 μl) solution of caspase-3 inhibitor Q-DEVD-OPh (Cat. No. 1175-1) in DMSO.Biovision | 1178 | EZSolution™...

Biovision | EZSolution™ Pyrintegrin | 1737

A 10 mM ( 1 mg in 221 µl) of Pyrintegrin (Cat. No. 1729-1) in anhydrous DMSO.EZSolution™ Pyrintegrin is a 10 mM ( 1 mg in 221 µl) of Pyrintegrin (Cat. No. 1729-1) in anhydrous DMSO.Biovision | 1737 | EZSolution™ Pyrintegrin DataSheetAlternate...

Biovision | EZSolution™ Puromycin Dihydrochloride | 1861

A solution (10 mg/ml, 0.2 µM sterile filtered) of Puromycin Dihydrochloride (Cat. No.1860-100) in deionized water. Suitable for cell culture applications.EZSolution™ Puromycin Dihydrochloride is a solution (10 mg/ml, 0.2 µM sterile filtered) of Puromycin...

Biovision | EZSolution™ Purmorphamine, Sterile-filtered | B2236

A 10 mM (5.0 mg in 960 μl), sterile-filtered solution of the Smoothened (Smo) Receptor Agonist Purmorphamine (Cat. No. 1672) in anhydrous DMSO.EZSolution™ Purmorphamine is a 10 mM (5.0 mg in 960 μl), sterile-filtered solution of the Smoothened (Smo)...

Biovision | EZSolution™ PS48 | 2638

A 10 mM (5 mg in 1744 µl) of the PDK1 activator PS48 (Cat. No. 1869) in anhydrous DMSO.PS48 is an allosteric phosphoinositide-dependent protein kinase-1 (PDK1) activator (Kd = 10.3 μM). Binds exclusively to the PIF-binding pocket of PDK1, distinct from...

Biovision | EZSolution™ PS-341 | 2145

A 10 mM (1 mg in 260 µl) solution of the proteasome inhibitor PS-341 (Cat. No. 1846) in anhydrous DMSO.EZSolution™ PS-341 is a 10 mM (1 mg in 260 µl) solution of the proteasome inhibitor PS-341 (Cat. No. 1846) in anhydrous DMSO.Biovision | 2145 |...

Biovision | EZSolution™ Pioglitazone | 9650

A 10 mM (5 mg in 1403 µl) of PPARγ agonist Pioglitazone (Cat. No. 1877) in anhydrous DMSO.Pioglitazone is a thiazolidinedione (TZD) derivative that acts as a selective peroxisome proliferator-activated receptor gamma (PPARγ) agonist (EC₅₀ = 0.69 μM). An...

Biovision | EZSolution™ PFI-1, Sterile-filtered | B2251

A 5 mM (2 mg in 1.15 ml), sterile-filtered solution of the BET bromodomain inhibitor PFI-1 (Cat. No. 2203) in anhydrous DMSO.EZSolution™ PFI-1 is a 5 mM (2 mg in 1.15 ml), sterile-filtered solution of the BET bromodomain inhibitor PFI-1 (Cat. No. 2203)...

Biovision | EZSolution™ Penicillin/Streptomycin/Amphotericin B, Sterile-Filtered (100X) | 2505

Supplied as a 100X concentrated sterile-filtered solution. Pencillin/Streptomycin/Amphotericin B contains 10,000 IU/ml of Penicillin potassium (Cat. No. 2504), 10 mg/ml of Streptomycin sulfate (Cat. No. 2501), and 25 μg/ml of Amphotericin B (Cat. No...

Biovision | EZSolution™ Penicillin/Streptomycin, Sterile-Filtered (100X) | 2502

Supplied as a 100X concentrated sterile-filtered solution. Pencillin-Streptomycin (Pen/Strep) is an antibacterial solution comprised of Penicillin (10,000 units/ml), a β-lactam, and Streptomycin (10 mg/ml), an aminoglycoside.Pencillin-Streptomycin...

Biovision | EZSolution™ PD184352 | 1871

A 10 mM (1 mg in 209 µl) solution of PD184352 (Cat. No. 1585-1) in anhydrous DMSO.EZSolution™ PD184352 is a A 10 mM (1 mg in 209 µl) solution of PD184352 (Cat. No. 1585-1) in anhydrous DMSO.Biovision | 1871 | EZSolution™ PD184352 DataSheetAlternate...

Biovision | EZSolution™ PD-0325901, Sterile-Filtered | 1990

A 5 mM (2.41 mg in 1 ml), sterile-filtered solution of the MEK inhibitor PD-0325901 (Cat. No. 1643) in anhydrous DMSO.EZSolution™ PD-0325901, Sterile-Filtered is a 5 mM (2.41 mg in 1 ml), sterile-filtered solution of the MEK inhibitor PD-0325901 (Cat. No...

Biovision | EZSolution™ PD 98059 | 1783

A 10 mM (5 mg in 1870 µl) solution of PD98059 (Cat. No. 1666-5) in anhydrous DMSO.EZSolution™ PD 98059 is a 10 mM (5 mg in 1870 µl) solution of PD98059 (Cat. No. 1666-5) in anhydrous DMSO.Biovision | 1783 | EZSolution™ PD 98059 DataSheetAlternate...

Biovision | EZSolution™ P7C3-A20 | B1505

A 10 mM (5.06 mg in 1 ml) solution of the neuroprotective agent P7C3-A20 (Cat. No. 2850) in anhydrous DMSO.P7C3-A20 is a derivative of P7C3 (Cat. No. 2849), and is a proneurogenic, neuroprotective agent. P7C3-A20 displays increased activity and an...

Biovision | EZSolution™ NU-7441 | B1875

A 5 mM (5.0 mg in 2.42 ml), sterile-filtered solution of the HDR (homology-directed repair) enhancer NU-7441 (Cat. No. B1117) in anhydrous DMSO.NU-7441 is a potent and selective DNA-PK inhibitor (IC₅₀ = 14 nM). Displays selectivity for DNA-PK over a...

Biovision | EZSolution™ Nocodazole | B1874

A 10 mM (5.0 mg in 1.66 ml), sterile-filtered solution of the HDR (homology-directed repair) enhancer Nocodazole (Cat. No. 2185) in anhydrous DMSO.Nocodazole is a microtubule inhibitor; inhibits mitosis. Disrupts microtubules by binding to β‑tubulin and...

Biovision | EZSolution™ Nimbolide | 9655

A 10 mM (5 mg in 1072 µl) of the terpenoid lactone Nimbolide (Cat. No. 1891) in anhydrous DMSO.Nimbolide is a terpenoid lactone derived from Azadirachta indica (Neem tree) that displays a variety of biological activities including anti-malarial and...

Biovision | EZSolution™ Necrosulfonamide, Sterile-Filtered | B1220

A 10 mM (10 mg in 2.17 ml), sterile-filtered solution of the necroptosis inhibitor Necrosulfonamide (Cat. No. 9635) in anhydrous DMSO.Necrosulfonamide is a potent necroptosis inhibitor. It blocks mixed lineage kinase domain-like protein (MLKL), a...

Biovision | EZSolution™ Nec-1s | 2535

A potent necroptosis inhibitor. Displays higher activity in inhibiting necroptosis in Jurkat cells than Nec-1 (Cat. No. 1864) (EC₅₀ = 210 nM versus EC₅₀ = 490 nM), as well as showing no nonspecific cytotoxicity at high concentrations (~100 mM). More...

Biovision | EZSolution™ MG-132 | 1791

A 10 mM (5 mg in 1051 µl) solution of MG-132 (Cat. No.1703-5) in anhydrous DMSO.EZSolution™ MG-132 is a 10 mM (5 mg in 1051 µl) solution of MG-132 (Cat. No.1703-5) in anhydrous DMSO.Biovision | 1791 | EZSolution™ MG-132 DataSheetAlternate Name/Synonyms:...

Biovision | EZSolution™ MG-115 | 2144

A 10 mM (1 mg in 217 µl) solution of the proteasome inhibitor MG-115 (Cat. No. 1831) in anhydrous DMSO.EZSolution™ MG-115 is a 10 mM (1 mg in 217 µl) solution of the proteasome inhibitor MG-115 (Cat. No. 1831) in anhydrous DMSO.Biovision | 2144 |...

Biovision | EZSolution™ MAFP | 2811

MAFP is a potent inhibitor of fatty acid amide hydrolase (FAAH) (IC₅₀ = 2.5 nM). MAFP also binds to the CB1 receptor in rat brain membrane preparations (IC₅₀ = 20 nM). MAFP also acts as a selective, active-site directed, irreversible inhibitor of cPLA2...

Biovision | EZSolution™ LY294002 | 1747

A 10 mM (5 mg/1627 µl) solution of PI -3 Kinase inhibitor LY 294002 (Cat. No.1667-5) in DMSO.EZSolution™ LY294002 is a 10 mM (5 mg/1627 µl) solution of PI -3 Kinase inhibitor LY 294002 (Cat. No.1667-5) in DMSO.Biovision | 1747 | EZSolution™ LY294002...

Biovision | EZSolution™ Liproxstatin-1 | B2355

A 10 mM (5 mg in 1.47 ml), sterile-filtered solution of the ferroptosis inhibitor Liproxstatin-1 (Cat. No. B2312) in anhydrous DMSOEZSolution™ Liproxstatin-1 is a 10 mM (5 mg in 1.47 ml), sterile-filtered solution of the ferroptosis inhibitor...

Biovision | LDN193189 HCl | 2092

A 10 mM (5 mg in 1.13 ml) solution of LDN193189 (Cat. No. 1995-5) in anhydrous DMSO.EZSolution™ LDN193189 is a 10 mM (5 mg in 1.13 ml) solution of LDN193189 (Cat. No. 1995-5) in anhydrous DMSO.Biovision | 2092 | LDN193189 HCl DataSheetAlternate...

Biovision | EZSolution™ Lapatinib Ditosylate | 2807

A 10 mM (10 mg in 1080 µl) of the EGFR inhibitor Lapatinib ditosylate (Cat. No.1624) in anhydrous DMSO.Lapatinib is a potent inhibitor of EGFR kinase (Ki = 3 nM), ErbB-2 kinase (Ki = 13 nM), ErbB-4 kinase (Ki = 347 nM). Lapatinib can restore tamoxifen...