Product Description
A-966492 is a potent PARP (poly (ADP-ribose) polymerase) inhibitor that displays potency against the PARP-1 enzyme with a K(i) of 1 nM and an EC₅₀ of 1 nM in a whole cell assay.
A-966492 is a potent PARP (poly (ADP-ribose) polymerase) inhibitor that displays potency against the PARP-1 enzyme with a K(i) of 1 nM and an EC₅₀ of 1 nM in a whole cell assay.
Biovision | B2174 | A-966492 DataSheet
Alternate Name/Synonyms: 2-[2-Fluoro-4-[(2S)-2-pyrrolidinyl]phenyl]-1H-benzimidazole-7-carboxamide
Appearance: White to off-white solid
Formulation: N/A
CAS Number: 934162-61-5
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₈H₁₇FN₄O
Molecular Weight: 324.4
Cell-Permeable?: Yes
Purity: ≥98%
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent PARP-1 inhibitor
MDL Number: N/A
PubChem CID: 16666333
SMILES: C1CC(NC1)C2=CC(=C(C=C2)C3=NC4=C(C=CC=C4N3)C(=O)N)F
InChi: InChI=1S/C18H17FN4O/c19-13-9-10(14-5-2-8-21-14)6-7-11(13
InChi Key: AHIVQGOUBLVTCB-AWEZNQCLSA-N