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Product Description
A37 is a aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor (IC₅₀ = 4.6 μM; Ki = 300 nM). Displays selectivity for ALDH1A1 over eight other ALDH isoforms. A37 disrupts OC spheroid formation and cell viability (p<0.001).
A37 is a aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor (IC₅₀ = 4.6 μM; Ki = 300 nM). Displays selectivity for ALDH1A1 over eight other ALDH isoforms. A37 disrupts OC spheroid formation and cell viability (p<0.001).
Biovision | B1577 | A37 DataSheet
Alternate Name/Synonyms: Ethyl 2-[[3,4-dihydro-4-oxo-3-[3-(1-pyrrolidinyl)propyl][1]benzothieno[3,2-d]pyrimidin-2-yl]thio]acetate; CM 037
Appearance: Beige solid
Formulation: N/A
CAS Number: 896795-60-1
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₂₁H₂₅N₃O₃S₂
Molecular Weight: 431.57
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>40 mg/ml) or EtOH (>30 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: An aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor
MDL Number: N/A
PubChem CID: 5049161
SMILES: CCOC(=O)CSC1=NC2=C(C(=O)N1CCCN3CCCC3)SC4=CC=CC=C42
InChi: InChI=1S/C21H25N3O3S2/c1-2-27-17(25)14-28-21-22-18-15-8-3-4-9-16(15)29-19(18)20(26)24(21)13-7-12-23-10-5-6-11-23/h3-4,8-9H,2,5-7,10-14H2,1H3
InChi Key: SKDRHRAYBYQVNU-UHFFFAOYSA-N
