Euro
USD
British Pound
NULL
Product Description
A highly potent and selective inhibitor of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3 (IC₅₀ = 88 nM). Displays >100-fold selectivity against AKR1C1, AKR1C2 and AKR1C4. Does not display any COX (cyclooxygenase) inhibition at 10 µM in whole blood assay.
AKR1C3 inhibitor III is a highly potent and selective inhibitor of the type 5 17-β-hydroxysteroid dehydrogenase AKR1C3 (IC₅₀ = 88 nM). Displays >100-fold selectivity against AKR1C1, AKR1C2 and AKR1C4.
Biovision | 2424 | AKR1C3 Inhibitor III DataSheet
Alternate Name/Synonyms: 4-(4-Chlorophenyl)piperazin-1-yl)(morpholino)methanone
Appearance: White to off-white solid
Formulation: N/A
CAS Number: N/A
Structure Available?: Yes
Peptide sequence: No
Salt Form: No
Molecular Formula: C₁₅H₂₀ClN₃O₂
Molecular Weight: 309.79
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent and selective AKR1C3 inhibitor
MDL Number: N/A
PubChem CID: N/A
SMILES: O=C(N1CCN(C2=CC=C(Cl)C=C2)CC1)N3CCOCC3
InChi: InChI=1S/C15H20ClN3O2/c16-13-1-3-14(4-2-13)17-5-7-18(8-6-17)15(20)19-9-11-21-12-10-19/h1-4H,5-12H2
InChi Key: KDSIRFZJOTZBPT-UHFFFAOYSA-N
