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Product Description
Cell-permeable. A potent activator of AMPK (AMP-activated protein kinase). The activation of AMPK was achieved through inhibition of NAD(P)H dehydrogenase [quinone] 1 (complex I). D942 increases glucose uptake in L6 myocytes, and inhibits CCL2-induced mTORC1 activity and survivin expression in human prostate cancer PC-3 cells.
D942 is a potent activator of AMPK (AMP-activated protein kinase).
Biovision | 2341 | AMPK Activator, D942 DataSheet
Alternate Name/Synonyms: 5-(3-(4-(2-(4-Fluorophenyl)ethoxy)phenyl)propyl)furan-2-carboxylic acid
Appearance: Light yellow solid
Formulation: N/A
CAS Number: 849727-81-7
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₂H₂₁FO₄
Molecular Weight: 368.4
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (10 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent AMPK activator
MDL Number: N/A
PubChem CID: 16760291
SMILES: C1=CC(=CC=C1CCCC2=CC=C(O2)C(=O)O)OCCC3=CC=C(C=C3)F
InChi: InChI=1S/C22H21FO4/c23-18-8-4-17(5-9-18)14-15-26-19-10-6-16(7-11-19)2-1-3-20-12-13-21(27-20)22(24)25/h4-13H,1-3,14-15H2,(H,24,25)
InChi Key: MPLLLQUZNJSVTK-UHFFFAOYSA-N
