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Product Description
A potent inhibitor of 5- and platelet 12-lipoxygenases (IC50 values are 9.5 and 0.12 μM respectively). Baicalein inhibits lipid peroxidation, as assessed by production of thiobarbituric acid (TBARS; IC₅₀= 5 µM), and inhibits growth of Huh-7, KIM-1, and HLF human hepatocellular carcinoma cells (IC₅₀s = 17-70 µg/ml).
Baicalein is a potent inhibitor of 5- and platelet 12-lipoxygenases (IC50 values are 9.5 and 0.12 μM respectively). Baicalein inhibits lipid peroxidation, as assessed by production of thiobarbituric acid (TBARS; IC₅₀= 5 µM), and inhibits growth of Huh-7, KIM-1, and HLF human hepatocellular carcinoma cells (IC₅₀s = 17-70 µg/ml).
Biovision | B2309 | Baicalein DataSheet
Alternate Name/Synonyms: 5,6,7-Trihydroxy-2-phenyl-(4H)-1-benzopyran-4-one
Appearance: Yellow solid
Formulation: N/A
CAS Number: 491-67-8
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₅H₁₀O₅
Molecular Weight: 270.24
Cell-Permeable?:
Purity: ≥98%
Solubilities: DMSO (>10 mg/ml)
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A potent inhibitor of 5- and platelet 12-lipoxygenases
MDL Number: MFCD00017459
PubChem CID: 5281605
SMILES: C1=CC=C(C=C1)C2=CC(=O)C3=C(C(=C(C=C3O2)O)O)O
InChi: InChI=1S/C15H10O5/c16-9-6-11(8-4-2-1-3-5-8)20-12-7-10(17)14(18)15(19)13(9)12/h1-7,17-19H
InChi Key: FXNFHKRTJBSTCS-UHFFFAOYSA-N
