Product Description
A potent, slow-binding competitive inhibitor of recombinant rat liver arginase I with a Ki of 0.4-0.6 µM. It is also a potent inhibitor of human arginase II with Ki values of 0.31 µM and 30 nM at pH 7.5 and 9.5, respectively. It does not inhibit murine iNOS at concentrations up to 1 mM. BEC significantly enhances NO-dependent relaxation of human penile corpus canvernosum smooth muscle in vitro at concentrations between 0.1-1.0 mM.
BEC is a potent, slow-binding competitive inhibitor of recombinant rat liver arginase I with a Ki of 0.4-0.6 µM. It is also a potent inhibitor of human arginase II with Ki values of 0.31 µM and 30 nM at pH 7.5 and 9.5, respectively.
Biovision | 2359 | BEC DataSheet
Alternate Name/Synonyms: S-(2-boronoethyl)-L-cysteine
Appearance: White solid
Formulation: N/A
CAS Number: 63107-40-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₅H₁₂BNO₄S
Molecular Weight: 193.03
Cell-Permeable?: Yes
Purity: ≥98%
Solubilities: PBS, pH 7.2 (~ 5 mg/ml)
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A potent arginase inhibitor
MDL Number: N/A
PubChem CID: 9877608
SMILES: B(CCSCC(C(=O)O)N)(O)O
InChi: InChI=1S/C5H12BNO4S/c7-4(5(8)9)3-12-2-1-6(10)11/h4,10-11H,1-3,7H2,(H,8,9)/t4-/m0/s1
InChi Key: OTJHLDXXJHAZTN-BYPYZUCNSA-N