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Product Description
Berbemine is a naturally occurring alkaloid that displays several biological properties. Berbamine potently suppresses liver cancer cell proliferation and induces cancer cell death by targeting Ca²⁺/calmodulin-dependent protein kinase II (CAMKII). Also acts as a novel inhibitor of NF-kappaB activity with remarkable anti-myeloma efficacy.
Berbemine is a naturally occurring alkaloid that displays several biological properties. Berbamine potently suppresses liver cancer cell proliferation and induces cancer cell death by targeting Ca²⁺/calmodulin-dependent protein kinase II (CAMKII). Also acts as a novel inhibitor of NF-kappaB activity with remarkable anti-myeloma efficacy.
Biovision | 2520 | Berbamine dihydrochloride DataSheet
Alternate Name/Synonyms: Berbenine
Appearance: Crystalline solid
Formulation: N/A
CAS Number: 6078-17-7
Structure Available?: Y
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₃₇H₄₂Cl₂N₂O₆
Molecular Weight: 681.65
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO or EtOH
Handling: Protect from air and moisture
Country of Origin: USA
Tag Line: A Ca²⁺/calmodulin-dependent kinase type II inhibitor
MDL Number: MFCD11982910
PubChem CID: 16217067
SMILES: CN1CCC2=CC(=C3C=C2C1CC4=CC=C(C=C4)OC5=C(C=CC(=C5)CC6C7=C(O3)C(=C(C=C7CCN6C)OC)OC)O)OC.Cl.Cl
InChi: InChI=1S/C37H40N2O6.2ClH/c1-38-14-12-24-19-32(41-3)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-31-18-23(8-11-30(31)40)17-29-35-25(13-15-39(29)2)20-34(42-4)36(43-5)37(35)45-33;;/h6-11,18-21,28-29,40H,12-17H2,1-5H3;2*1H/t28-,29+;;/m0../s1
InChi Key: USRXDYNDPPUBSG-KKXMJGKMSA-N
