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Product Description
Bexarotene is a synthetic retinoid analog with specific affinity for the retinoid X receptor and belongs to a group of compounds called rexinoids. It is an oral, noncytotoxic drug that was approved in Europe and in the U.S.A. for the treatment of refractory advanced-stage cutaneous T-cell lymphomas. The receptor-selective retinoids might be particularly useful in preventing ER-negative breast cancer.
Bexarotene is a synthetic retinoid analog with specific affinity for the retinoid X receptor and belongs to a group of compounds called rexinoids. Acts as an antineoplastic agent.
Biovision | 1575 | Bexarotene DataSheet
Alternate Name/Synonyms: Targretin, LGD-1069, LG-1069, LG10069, SR-11247
Appearance: Off-white solid
Formulation: N/A
CAS Number: 153559-49-0
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₂₄H₂₈O₂
Molecular Weight: 348.48
Cell-Permeable?: Yes
Purity: ≥99%
Solubilities: DMSO
Handling: Protect from light and air
Country of Origin: USA
Tag Line: An antineoplastic agent
MDL Number: MFCD00932428
PubChem CID: 82146
SMILES: CC1=CC2=C(C=C1C(=C)C3=CC=C(C=C3)C(=O)O)C(CCC2(C)C)(C)C
InChi: InChI=1S/C24H28O2/c1-15-13-20-21(24(5,6)12-11-23(20,3)4)14-19(15)16(2)17-7-9-18(10-8-17)22(25)26/h7-10,13-14H,2,11-12H2,1,3-6H3,(H,25,26)
InChi Key: NAVMQTYZDKMPEU-UHFFFAOYSA-N
