Product Description
BG-45 is a potent HDAC class I inhibitor with selectivity for HDAC3 (IC₅₀ = 289 nM) over HDAC1, 2. BG45 does not inhibit HDAC6. BG-45 alone or in combination with bortezomib has been shown to dose-dependently inhibit tumor growth in a mouse model of multiple myeloma.
BG-45 is a potent HDAC class I inhibitor with selectivity for HDAC3 (IC₅₀ = 289 nM) over HDAC1, 2. BG45 does not inhibit HDAC6. BG-45 alone or in combination with bortezomib has been shown to dose-dependently inhibit tumor growth in a mouse model of multiple myeloma.
Biovision | B1866 | BG-45 DataSheet
Alternate Name/Synonyms: N-(2-Aminophenyl)pyrazine-2-carboxamide
Appearance: White to of-white solid
Formulation: N/A
CAS Number: 926259-99-6
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: N/A
Molecular Formula: C₁₁H₁₀N₄O
Molecular Weight: 214.23
Cell-Permeable?: Yes
Purity: ≥98% by HPLC
Solubilities: DMSO (>20 mg/ml)
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A potent HDAC class I inhibitor
MDL Number: N/A
PubChem CID: 16773791
SMILES: C1=CC=C(C(=C1)N)NC(=O)C2=NC=CN=C2
InChi: InChI=1S/C11H10N4O/c12-8-3-1-2-4-9(8)15-11(16)10-7-13-5-6-14-10/h1-7H,12H2,(H,15,16)
InChi Key: LMWPVSNHKACEKW-UHFFFAOYSA-N