Euro
USD
British Pound
NULL
Product Description
A synthetic peptide that irreversibly inhibits activity of caspase family proteases and blocks apoptosis. The inhibitor is designed as a methyl ester to enhance cell permeability. The conjugation with biotin allows detection of activated caspases in conjunction with avidin-tags. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).
Biotin-VAD-FMK is biotinylated derivative of the pan-caspase inhibitor (Cat. No. 1010).
Biovision | 1123 | Biotin-VAD-FMK DataSheet
Alternate Name/Synonyms: Biotin-VAD-FMK , VAD-FMK, Biotin-
Appearance: Liquid
Formulation: DMSO (10 mM)
CAS Number: N/A
Structure Available?: No
Peptide sequence: Biotin-Val-Ala-Asp(OMe)-FMK
Salt Form: No
Molecular Formula: C₃₀H₄₉FN₆O₈S
Molecular Weight: 672.81
Cell-Permeable?: Yes
Purity: >95% by HPLC
Solubilities: N/A
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A pan-caspase inhibitor
MDL Number: N/A
PubChem CID: 44135213
SMILES: CC(C)C(C(=O)NC(C)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)CCCCCNC(=O)CCCCC1C2C(CS1)NC(=O)N2
InChi: InChI=1S/C30H49FN6O8S/c1-17(2)26(29(43)33-18(3)28(42)34-19(21(38)15-31)14-25(41)45-4)36-24(40)12-6-5-9-13-32-23(39)11-8-7-10-22-27-20(16-46-22)35-30(44)37-27/h17-20,22,26-27H,5-16H2,1-4H3,(H,32,39)(H,33,43)(H,34, 42)(H,36,40)(H2,35,37,44)
InChi Key: MOQLQMKJGYKHCT-UHFFFAOYSA-N
