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Product Description
1,10-Phenanthroline is a metal chelator and inhibitor of metalloproteases. 1,10-Phenanthrine acts as a fungistatic against P. verrucosa (MIC = 0.8 μg/ml) and inhibits zinc-induced P. verrucosa metallo-type peptidase activity in a concentration-dependent manner. It reduces the expression of matrix metalloproteinase (MMP3) during chondrogenic differentiation of human chondrocytes.
1,10-Phenanthroline is a metal chelator and inhibitor of metalloproteases. 1,10-Phenanthrine acts as a fungistatic against P. verrucosa (MIC = 0.8 μg/ml) and inhibits zinc-induced P. verrucosa metallo-type peptidase activity in a concentration-dependent manner. It reduces the expression of matrix metalloproteinase (MMP3) during chondrogenic differentiation of human chondrocytes.
Biovision | B3122 | 1,10-Phenanthroline DataSheet
Alternate Name/Synonyms: 2-Phenanthroline; 4,5-Diazaphenanthrene; o-Phenanthroline; 5,6-dihydro-1,10-phenanthroline
Appearance: Off-white solid
Formulation:
CAS Number: 66-71-7
Structure Available?: TRUE
Peptide sequence:
Salt Form: FALSE
Molecular Formula: C₁₂H₈N₂
Molecular Weight: 180.2
Cell-Permeable?: True
Purity: ≥ 98%
Solubilities: ~18 mg/ml in DMSO or Ethanol
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: A metal chelator and inhibitor of metalloproteases
MDL Number: MFCD00011678
PubChem CID: 1318
SMILES: C1=CC2=C(C3=C(C=CC=N3)C=C2)N=C1
InChi: InChI=1S/C12H8N2/c1-3-9-5-6-10-4-2-8-14-12(10)11(9)13-7-1/h1-8H
InChi Key: DGEZNRSVGBDHLK-UHFFFAOYSA-N
