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Product Description
2-arachidonoylglycerol is an endocannabinoid and an endogenous agonist of the cannabinoid G-protein coupled receptors (CB1 and CB2) with Ki values of 472 nM and 1400 nM respectively. 2-arachidonoylglycerol induces a rapid, transient increase in intracellular free calcium in NG108-15 cells at a concentration of 0.3 nM, through a CB1 receptor-dependent mechanism. It is present at relatively high levels in the brain when compared to anandamide.
2-arachidonoylglycerol is an endocannabinoid and an endogenous agonist of the cannabinoid G-protein coupled receptors (CB1 and CB2) with Ki values of 472 nM and 1400 nM respectively. 2-arachidonoylglycerol induces a rapid, transient increase in intracellular free calcium in NG108-15 cells at a concentration of 0.3 nM, through a CB1 receptor-dependent mechanism. It is present at relatively high levels in the brain when compared to anandamide.
Biovision | B2992 | 2-Arachidonoylglycerol DataSheet
Alternate Name/Synonyms: 1,3-dihydroxypropan-2-yl (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoate; Glyceryl 2-arachidonate; (5Z,8Z,11Z,14Z)-1,3-dihydroxypropan-2-yl icosa-5,8,11,14-tetraenoate
Appearance: Colorless Solution
Formulation: A solution in acetonitrile (as a 9:1 mixture of the 2-AG and 1-AG)
CAS Number: 53847-30-6
Structure Available?: True
Peptide sequence:
Salt Form: False
Molecular Formula: C₂₃H₃₈O₄
Molecular Weight: 378.55
Cell-Permeable?: False
Purity: ≥95%
Solubilities: ~150 μg/ml in PBS, pH 7.2, ~10 mg/ml in DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An endocannabinoid and an agonist of CB1 and CB2
MDL Number: MFCD01862600
PubChem CID: 5282280
SMILES: CCCCCC=CCC=CCC=CCC=CCCCC(=O)OC(CO)CO
InChi: InChI=1S/C23H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(26)27-22(20-24)21-25/h6-7,9-10,12-13,15-16,22,24-25H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-
InChi Key: RCRCTBLIHCHWDZ-DOFZRALJSA-N
